5,12-Naphthacenedione, 10-[(6-deoxy-2-O-methyl-α-L-mannopyranosyl)oxy]-7,8,9,10-tetrahydro-1,8,11-trihydroxy-8-methyl-, (8R,10S)- Chemical Properties

Boiling point:

707.3±60.0 °C(Predicted)

Density 

1.55±0.1 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

DMSO: soluble; Methanol: soluble

form 

A solid

pka

6.62±0.60(Predicted)

5,12-Naphthacenedione, 10-[(6-deoxy-2-O-methyl-α-L-mannopyranosyl)oxy]-7,8,9,10-tetrahydro-1,8,11-trihydroxy-8-methyl-, (8R,10S)- Usage And Synthesis

Uses

Aranciamycin A is an anthracyclic antibiotic and can be isolated from Streptomyces. Aranciamycin A shows antibacterial activity against M. bovis and B. subtilis with the MIC values of 30 and 7.5 μM, respectively[1].

Biological Activity

Aranciamycin A is an anthracyclic antibiotic that has been found in Streptomyces.1 It is active against M. bovis and B. subtilis (MICs = 30 and 7.5 μM, respectively) but not S. aureus, E. coli, P. aeruginosa, or C. albicans (MICs = >30 μM for all).

References

1.Khalil, Z.G., Raju, R., Piggott, A.M., et al.Aranciamycins I and J, antimycobacterial anthracyclines from an Australian marine-derived Streptomyces spJ. Nat. Prod.78(4)949-952(2015)