1-methyl-4-phenylpiperidine-4-carbonitrile
1-methyl-4-phenylpiperidine-4-carbonitrile Basic information
- Product Name:
- 1-methyl-4-phenylpiperidine-4-carbonitrile
- Synonyms:
-
- 1-methyl-4-phenylpiperidine-4-carbonitrile
- 4-CYANO-1-METHYL-4-PHENYLPIPERIDINE
- 3-Methyl-4-phenyl-4-piperidinenitrile
- 1-Methyl-4-phenyl-4-piperidinecarbonitrile
- CAS:
- 3627-62-1
- MF:
- C13H16N2
- MW:
- 200.28
- EINECS:
- 222-847-7
- Mol File:
- 3627-62-1.mol
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1-methyl-4-phenylpiperidine-4-carbonitrile Chemical Properties
- Melting point:
- 53 °C
- Boiling point:
- 148 °C(Press: 4.5 Torr)
- Density
- 1.07±0.1 g/cm3(Predicted)
- pka
- 6.82±0.10(Predicted)
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1-methyl-4-phenylpiperidine-4-carbonitrile Usage And Synthesis
Chemical Properties
crystallization. Melting point 53 ℃. Boiling point 148/544Pa (4mmHg).
Uses
1-methyl-4-phenylpiperidine-4-carbonitrile can be used as an intermediate in the synthesis of meperidine (Meluidine).
Synthesis
1-methyl-4-phenylpiperidine-4-carbonitrile is prepared by reacting by bis (β-chloroethyl) methylamine hydrochloride and benzyl cyanide condensation in the participation of sodium amide.