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ChemicalBook >  Product Catalog >  Biologics >  Dyes/Staining Agents >  2-[3-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)prop-1-enyl]-1,3,3-trimethyl-3H-indolium iodide

2-[3-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)prop-1-enyl]-1,3,3-trimethyl-3H-indolium iodide

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2-[3-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)prop-1-enyl]-1,3,3-trimethyl-3H-indolium iodide Basic information

Product Name:
2-[3-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)prop-1-enyl]-1,3,3-trimethyl-3H-indolium iodide
Synonyms:
  • 2-[3-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)prop-1-enyl]-1,3,3-trimethyl-3H-indolium iodide
  • 1,1',3,3,3',3'-hexamethylindocarbocyanine
  • 3H-Indolium, 2-[3-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1-propenyl]-1,3,3-trimethyl-, iodide
  • 1,3,3,1'',3'',3''-Hexamethyl-2,2''-indocarbocyanine iodide
  • 2-[3-(1,3,3-Trimethyl-2,3-dihydro-1H-indole-2-ylidene)-1-propenyl]-1,3,3-trimethyl-3H-indole-1-ium·iodide
  • 2-[3-(1,3,3-Trimethylindoline-2-ylidene)-1-propenyl]-1,3,3-trimethyl-3H-indole-1-ium·iodide
  • 2-[3-(1,3,3-Trimethylindoline-2-ylidene)-1-propenyl]-1,3,3-trimethyl-3H-indolium·iodide
  • NK-79
CAS:
25470-94-4
MF:
C25H29IN2
MW:
484.41563
EINECS:
247-014-5
Mol File:
25470-94-4.mol
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2-[3-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)prop-1-enyl]-1,3,3-trimethyl-3H-indolium iodide Chemical Properties

Melting point:
223 °C (decomp)
solubility 
Soluble in DMSO, DMF, methanol
Appearance
Red paint-like solid
ex/em
550/570 nm (MeOH)
EPA Substance Registry System
3H-Indolium, 2-[3-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1-propenyl]-1,3,3-trimethyl-, iodide (25470-94-4)
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Safety Information

TSCA 
TSCA listed
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2-[3-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)prop-1-enyl]-1,3,3-trimethyl-3H-indolium iodide Usage And Synthesis

Description

Non-functionalized Сyanine3 dye derivative with an aliphatic side chain. Cyanine3 dimethyl is a non-sulfonated bright yellow emitting cyanine dye with good solubility in organic solvents. The dye can be used as a non-reactive fluorophore, for control experiments, and for calibration.

Chemical Properties

Appearance: Red lacquer-like solid
ex/em: 550/570 nm (MeOH)
Intracellular distribution: Membrane & lipid

Uses

Cy3 dimethyl iodide is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) with a dimethyl group in the iodide salt form. The iodide salt form increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy3 is a near-infrared fluorescent dye commonly used in biolabeling and cell imaging. Cy3 dimethyl iodide binds to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.

Abs/Em Maxima

555/570 nm

Fluoresene quantum yield

0.31

Extinction Coefficient

150000

CF260

0.04

CF280

0.09

2-[3-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)prop-1-enyl]-1,3,3-trimethyl-3H-indolium iodideSupplier

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2-[3-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)prop-1-enyl]-1,3,3-trimethyl-3H-indolium iodide(25470-94-4)Related Product Information