2-bromophenylhydrazine Chemical Properties

Melting point:

46-48 °C

Boiling point:

275.7±23.0 °C(Predicted)

Density 

1.666±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

pka

4.59±0.10(Predicted)

Appearance

Yellow to brown Solid

2-bromophenylhydrazine Usage And Synthesis

Synthesis

The general procedure for the synthesis of toluene and 2-bromophenylhydrazine from 2-bromotoluene was as follows: in an 8 mL screw-capped test tube, the indicated amounts of CuBr, ligand, phase transfer catalyst (PTC), and 50 mg of water were mixed well. Subsequently, 1 mmol of aryl halide and 10 mol% of the indicated amount of base were added, and the resulting mixture was stirred at a set temperature (bath temperature) for 10 min. Next, the remaining amount of base and the specified amount of hydrazine hydrate (N2H4-H2O) were added. The reaction mixture was continued to be stirred in a closed test tube at the same temperature for 1 hour. After completion of the reaction, it was cooled to room temperature and extracted with 5 mL of ethyl acetate (EtOAc). A 0.1 to 0.2 mL sample of the organic phase was dried over anhydrous sodium sulfate (Na2SO4) and analyzed by gas chromatography (GC).

References

[1] Tetrahedron, 2014, vol. 70, # 26, p. 4043 - 4048

2-bromophenylhydrazine(16732-66-4)Related Product Information

• 2-Bromophenylhydrazine hydrochloride
• 2-bromophenylhydrazine
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• AURORA KA-199
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• 1H-ISOCHROMENE-1,3,4-TRIONE 4-[N-(2,4-DIBROMOPHENYL)HYDRAZONE]
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• AURORA KA-196
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• (2-BROMO-4-BUTYL-PHENYL)-HYDRAZINE