1-(tert-butylamino)-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-2-ol
1-(tert-butylamino)-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-2-ol Basic information
- Product Name:
- 1-(tert-butylamino)-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-2-ol
- Synonyms:
-
- 1-[(1,1-Dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-2-propanol
- 1,2,5-Thiadiazole, 2-propanol deriv.
- 2-Propanol, 1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]- (8CI)
- 2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]- (9CI)
- Racemic timolol
- (+/-)-Timolol-d5 Maleate
- 1-[(1,1-Dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-2-propanol-d5 Maleate
- 3-Morpholino-4-(3-tert-butylamino-2-hydroxypropoxy)-1,2,5-thiadiazole-d5 Maleate
- CAS:
- 29023-48-1
- MF:
- C13H24N4O3S
- MW:
- 316.42
- EINECS:
- 249-374-9
- Product Categories:
-
- Amines
- Heterocycles
- Intermediates & Fine Chemicals
- Isotope Labeled Compounds
- Pharmaceuticals
- Isotope Labelled Compounds
- Mol File:
- 29023-48-1.mol
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1-(tert-butylamino)-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-2-ol Chemical Properties
- Melting point:
- 210-212°C
- Boiling point:
- 487.2±45.0 °C(Predicted)
- Density
- 1.224±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 13.38±0.20(Predicted)
- color
- White
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1-(tert-butylamino)-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-2-ol Usage And Synthesis
Chemical Properties
White Solid
Uses
Antihypertensive; antiarrhythmic (class II); antianginal; antiglaucoma agent
Uses
rac Timolol Maleate is an antihypertensive and antiarrhythmic. It can be used to treat hemangioma and vascular anomaly.
Definition
ChEBI: Timolol is 1,2,5-Thiadiazole substituted at the 3 position by a 3-(tert-butylamino)-2-hydroxypropoxy group and at the 4 position by a morpholin-4-yl group. The (S)-(-) enantiomer, also known as timolol, is a beta-adrenergic antagonist and is used in the mangement of glaucoma, hypertension, angina pectoris and myocardial infarction, and for the prevention of migraine. It is a member of thiadiazoles and a member of morpholines. It derives from a hydride of a 1,2,5-thiadiazole.
1-(tert-butylamino)-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-2-ol Supplier
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