BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE
- Product Name
- BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE
- CAS No.
- 184951-87-9
- Chemical Name
- BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE
- Synonyms
- BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE;(S)-2-(Boc-amino)-3-phenyl propanethioic O-acid-1-;(S)-2-(BOC-AMINO)-PRPPNETHIOIC O-ACID-1-(6-NITRO)BENZOTRIAZOLIDE;BOC-L-2-AMINO-3-PHENYLPROPANETHIOIC ACID-1-(6-NITRO)BENZOTRIAZOLIDE;(S)-2-(BOC-AMINO)-3-PHENYL-PROPANETHIOIC O-ACID-1-(6-NITRO)BENZOTRIAZOLIDE;(S)-2-[(t-Butoxycarbonyl)amino]-1-(6-nitrobenzotriazol-1-yl)-3-phenylpropane-1-thione;N-ALPHA-T-BUTOXYCARBONYL-L-2-AMINO-3-PHENYLPROPANETHIOIC ACID-1-(6-NITRO) BENZOTRIAZOLIDE;tert-butyl N-[(2S)-1-(6-nitrobenzotriazol-1-yl)-3-phenyl-1-sulfanylidenepropan-2-yl]carbamate;[(1S)-2-(6-Nitro-1H-benzotriazol-1-yl)-1-(phenylmethyl)-2-thioxoethyl]carbamic acid tert-butyl ester;Carbamic acid, [(1S)-2-(6-nitro-1H-benzotriazol-1-yl)-1-(phenylmethyl)-2-thioxoethyl]-, 1,1-dimethylethyl ester (9CI)
- CBNumber
- CB0753852
- Molecular Formula
- C20H21N5O4S
- Formula Weight
- 427.48
- MOL File
- 184951-87-9.mol
BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE Property
- Density
- 1.36
- storage temp.
- -15°C
- pka
- 10.06±0.46(Predicted)
N-Bromosuccinimide Price
- Product number
- FB111268
- Product name
- Boc-Thionophe-1-(6-nitro)benzotriazolide
- Packaging
- 250mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- FB111268
- Product name
- Boc-Thionophe-1-(6-nitro)benzotriazolide
- Packaging
- 500mg
- Price
- $260
- Updated
- 2021/12/16
- Product number
- FB111268
- Product name
- Boc-Thionophe-1-(6-nitro)benzotriazolide
- Packaging
- 1g
- Price
- $453
- Updated
- 2021/12/16
- Product number
- CCH0007944
- Product name
- (S)-2-(BOC-AMINO)-3-PHENYL PROPANETHIOIC O-ACID-1-(6-NITRO)BENZOTRIAZOLIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $497.43
- Updated
- 2021/12/16
- Product number
- 0001CS
- Product name
- Boc-ThionoPhe-1-(6-nitro)benzotriazolide
- Packaging
- 1g
- Price
- $661
- Updated
- 2021/12/16
BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE Chemical Properties,Usage,Production
Uses
BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Synthesis
To a solution of thioanilide 7 (2 mmol) dissolved
by gentle warming at 40 °C and then cooled to 0 °C in glacial
acetic acid (diluted with 5% water, 15 mL) was added NaNO2
(0.21 g, 3 mmol) in portions over 5 min with stirring. After 30
min, ice water (~100 mL) was added, and the precipitated
product was filtered and washed with water. The orange solid
was dried in vacuo at rt overnight and then at 50 °C for 4 h to
afford benzotriazoles 1-(N-BOC-L-thionophenylalaninyl)-6-nitrobenzotriazole (9b): yield 81%. as amorphous solids of
sufficient purity for use in the next step.
BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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