VICRIVIROC MALEATE
- Product Name
- VICRIVIROC MALEATE
- CAS No.
- 599179-03-0
- Chemical Name
- VICRIVIROC MALEATE
- Synonyms
- SCH-D;CS-1868;Unii-ep3qg127N9;SCH-D (maleate);SCH-417690; SCH-D;VICRIVIROC MALEATE;SCH-417690 (maleate);vicriviroc Maleate salt;VICRIVIROC MALEATE: SCH-D;Vicriviroc Malate(maleate)
- CBNumber
- CB01011681
- Molecular Formula
- C32H42F3N5O6
- Formula Weight
- 649.7009896
- MOL File
- 599179-03-0.mol
VICRIVIROC MALEATE Property
- storage temp.
- Store at -20°C
- solubility
- DMSO : 50 mg/mL (76.96 mM; Need ultrasonic)H2O : 25 mg/mL (38.48 mM; Need ultrasonic and warming)
- form
- Powder
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H319Causes serious eye irritation
H373May cause damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P314Get medical advice/attention if you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- SML2768
- Product name
- Vicriviroc Maleate
- Purity
- ≥98% (HPLC)
- Packaging
- 1MG
- Price
- $94.2
- Updated
- 2024/03/01
- Product number
- SML2768
- Product name
- Vicriviroc Maleate
- Purity
- ≥98% (HPLC)
- Packaging
- 5MG
- Price
- $381
- Updated
- 2024/03/01
- Product number
- 28453
- Product name
- Vicriviroc (maleate)
- Packaging
- 1mg
- Price
- $86
- Updated
- 2024/03/01
- Product number
- 28453
- Product name
- Vicriviroc (maleate)
- Packaging
- 10mg
- Price
- $421
- Updated
- 2024/03/01
- Product number
- 28453
- Product name
- Vicriviroc (maleate)
- Packaging
- 5mg
- Price
- $274
- Updated
- 2024/03/01
VICRIVIROC MALEATE Chemical Properties,Usage,Production
Description
Vicriviroc is a chemokine (C-C motif) receptor 5 (CCR5) antagonist (Ki = 2.5 nM). It selectively inhibits CCR5 over M1 and M2 muscarinic acetylcholine receptors (Kis = >10,000 nM for both) and human-ether-a-go-go (hERG) potassium channels (IC50 = 5.8 μM). Vicriviroc decreases chemotaxis induced by chemokine (C-C motif) ligand 3 (CCL3) in Ba/F3 cells expressing recombinant human CCR5 with an IC50 value of 0.91 nM. It inhibits the replication of 30 R5-tropic HIV-1 clinical isolates in peripheral blood mononuclear cells (PBMCs; EC50s = 0.04-1.4 nM) and reduces viral entry of seven drug-resistant strains of HIV-1 in U87 cells expressing CD4 and CCR5 (EC50s = 8.7-32.9 nM).
Uses
Antiviral, CCR5 antagonist, treatment of autoimmune conditions.
VICRIVIROC MALEATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from VICRIVIROC MALEATE manufacturers
- Product
- Vicriviroc maleate 599179-03-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- Vicriviroc maleate 599179-03-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-08