Preparation
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N-(tert-Butyl)benzylamine

Preparation
Product Name
N-(tert-Butyl)benzylamine
CAS No.
3378-72-1
Chemical Name
N-(tert-Butyl)benzylamine
Synonyms
N-Benzyl-2-Methylpropan-2-aMine;AI3-23247;AKOS BC-1243;N-t-Butylbenzylamine;N-Benzylisobutylamine;N-BENZYL-T-BUTYLAMINE;Elobixibat Impurity 5;TERT-BUTYL-BENZYLAMINE;N-TERT-BUTYLBENZYLAMINE;benzyl-tert-butyl-amine
CBNumber
CB0104133
Molecular Formula
C11H17N
Formula Weight
163.26
MOL File
3378-72-1.mol
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N-(tert-Butyl)benzylamine Property

Melting point:
-25 °C
Boiling point:
80 °C5 mm Hg(lit.)
Density 
0.881 g/mL at 25 °C(lit.)
vapor pressure 
12.1Pa at 25℃
refractive index 
n20/D 1.497(lit.)
Flash point:
176 °F
storage temp. 
Store below +30°C.
solubility 
2g/l
pka
9.77±0.29(Predicted)
form 
Oil
color 
Colourless
Water Solubility 
2 g/L (20 ºC)
Sensitive 
Air Sensitive
BRN 
507464
Dielectric constant
3.2400000000000002
InChIKey
DLSOILHAKCBARI-UHFFFAOYSA-N
LogP
2.9 at 25℃
CAS DataBase Reference
3378-72-1(CAS DataBase Reference)
NIST Chemistry Reference
Benzenemethanamine, N-(1,1-dimethylethyl)-(3378-72-1)
EPA Substance Registry System
Benzenemethanamine, N-(1,1-dimethylethyl)- (3378-72-1)
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Safety

Hazard Codes 
C,Xi
Risk Statements 
34-22-36/37/38
Safety Statements 
23-24/25-36-26-45-36/37/39
RIDADR 
2735
WGK Germany 
3
TSCA 
Yes
HazardClass 
8
PackingGroup 
III
HS Code 
29214980
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H227Combustible liquid

H301Toxic if swalloed

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
B1176
Product name
N-tert-Butylbenzylamine
Purity
>96.0%(GC)
Packaging
25mL
Price
$38
Updated
2024/03/01
TCI Chemical
Product number
B1176
Product name
N-tert-Butylbenzylamine
Purity
>96.0%(GC)
Packaging
500mL
Price
$453
Updated
2024/03/01
Alfa Aesar
Product number
L01146
Product name
N-Benzyl-tert-butylamine, 96%
Packaging
25g
Price
$76.65
Updated
2024/03/01
Alfa Aesar
Product number
L01146
Product name
N-Benzyl-tert-butylamine, 96%
Packaging
100g
Price
$207.65
Updated
2024/03/01
TRC
Product number
D462415
Product name
N-(1,1-Dimethylethyl)benzenemethanamine
Packaging
25g
Price
$80
Updated
2021/12/16
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N-(tert-Butyl)benzylamine Chemical Properties,Usage,Production

Preparation

N-(tert-Butyl)benzylamine can be prepared by refluxing condensation of tert-butylamine and benzyl chloride in dimethylformamide.

Chemical Properties

CLEAR COLOURLESS TO PALE YELLOW LIQUID

Uses

N-Benzyl-tert-butylamine, is used as a protected amine. It aids in the oxidation to the corresponding hydroxylamine and nitrone.

Synthesis Reference(s)

Tetrahedron Letters, 36, p. 9555, 1995 DOI: 10.1016/0040-4039(95)02046-2

Purification Methods

Dissolve the amine in Et2O, dry it over KOH pellets, filter and fractionate it in a N2 atmosphere to avoid reaction with CO2 from the air. The hydrochloride has m 245-246o(dec) (from MeOH/Me2CO) and the perchlorate has m 200-201o. [Freidfelder et al. J Am Chem Soc 80 4320 1958, Beilstein 12 IV 2166.]

N-(tert-Butyl)benzylamine Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(tert-Butyl)benzylamine Suppliers

UkrOrgSynthesis Ltd.
Tel
--
Fax
--
Email
y.barysheva@ukrorgsynth.com
Country
Ukraine
ProdList
6230
Advantage
38
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View Lastest Price from N-(tert-Butyl)benzylamine manufacturers

airuikechemical co., ltd.
Product
n-(tert-butyl)benzylamine 3378-72-1
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
200tons
Release date
2024-04-08
Shaanxi Dideu Medichem Co. Ltd
Product
N-(tert-Butyl)benzylamine 3378-72-1
Price
US $1.00/Kg
Min. Order
1Kg
Purity
98%
Supply Ability
20T
Release date
2024-07-19
Zhuozhou Wenxi import and Export Co., Ltd
Product
N-(tert-Butyl)benzylamine 3378-72-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-10

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