Ethanone, 1-(3-methoxy-2-pyridinyl)- (9CI)
- Product Name
- Ethanone, 1-(3-methoxy-2-pyridinyl)- (9CI)
- CAS No.
- 379227-03-9
- Chemical Name
- Ethanone, 1-(3-methoxy-2-pyridinyl)- (9CI)
- Synonyms
- 2-acetyl-3-Methoxypyridine;1-(3-Methoxy-2-pyridyl)ethanone;1-(3-Methoxy-2-pyridinyl)ethanone;Ethanone, 1-(3-methoxy-2-pyridinyl)-;1-(3-methoxypyridin-2-yl)ethan-1-one;Ethanone, 1-(3-methoxy-2-pyridinyl)- (9CI)
- CBNumber
- CB01046094
- Molecular Formula
- C8H9NO2
- Formula Weight
- 151.16
- MOL File
- 379227-03-9.mol
Ethanone, 1-(3-methoxy-2-pyridinyl)- (9CI) Property
- Boiling point:
- 238.8±20.0 °C(Predicted)
- Density
- 1.093±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 2.47±0.10(Predicted)
- Appearance
- Colorless to off-white Solid-Liquid Mixture
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- OR918940
- Product name
- 1-(3-Methoxypyridin-2-yl)ethanone
- Purity
- 95%
- Packaging
- 250mg
- Price
- $145
- Updated
- 2021/12/16
- Product number
- Z4678
- Product name
- 1-(3-Methoxypyridin-2-yl)ethanone
- Packaging
- 1g
- Price
- $253
- Updated
- 2021/12/16
- Product number
- OR918940
- Product name
- 1-(3-Methoxypyridin-2-yl)ethanone
- Purity
- 95%
- Packaging
- 1g
- Price
- $254
- Updated
- 2021/12/16
- Product number
- CHM0386763
- Product name
- 1-(3-METHOXYPYRIDIN-2-YL)ETHANONE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.3
- Updated
- 2021/12/16
- Product number
- OR918940
- Product name
- 1-(3-Methoxypyridin-2-yl)ethanone
- Purity
- 95%
- Packaging
- 5g
- Price
- $617
- Updated
- 2021/12/16
Ethanone, 1-(3-methoxy-2-pyridinyl)- (9CI) Chemical Properties,Usage,Production
Synthesis
917-64-6
24059-89-0
379227-03-9
Under nitrogen protection, 2-cyano-3-methoxypyridine (0.88 g, 6.5 mmol) was dissolved in a three-necked flask containing 20 mL of anhydrous tetrahydrofuran. The reaction system was cooled to 0 °C, followed by slow dropwise addition of tetrahydrofuran solution of methylmagnesium iodide (3 M, 4.3 mL, 12.8 mmol). The reaction temperature was maintained at 0 °C with continuous stirring for 2 hours. Upon completion of the reaction, the reaction was quenched by the slow addition of 50 mL of water at 0 °C. The pH of the reaction solution was adjusted to 7 with 2 N hydrochloric acid and subsequently extracted with ethyl acetate (3 x 50 mL). The organic phases were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure to give the crude product. Purification by silica gel column chromatography (eluent: hexane/ethyl acetate, gradient 0-100%) afforded the target compound 1-(3-methoxypyridin-2-yl)ethanone as a colorless oil (0.79 g, yield 79%). The product was confirmed by 1H-NMR (CDCl3): δ 8.42 (dd, J = 7.7, 1.4 Hz, 1H), 7.63 (dd, J = 7.6, 1.4 Hz, 1H), 7.61 (dd, J = 7.7, 7.6 Hz, 1H), 3.82 (s, 3H), 2.14 (s, 3H). Mass spectrum (ESI+): m/z 152 ([M+H]+).
References
[1] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 17, p. 5352 - 5359
[2] Patent: WO2015/187934, 2015, A1. Location in patent: Paragraph 0206
Ethanone, 1-(3-methoxy-2-pyridinyl)- (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
Ethanone, 1-(3-methoxy-2-pyridinyl)- (9CI) Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@chemsworth.com
- Country
- India
- ProdList
- 6700
- Advantage
- 30
View Lastest Price from Ethanone, 1-(3-methoxy-2-pyridinyl)- (9CI) manufacturers
- Product
- Ethanone, 1-(3-methoxy-2-pyridinyl)- (9CI) 379227-03-9
- Price
- US $5.50/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 1kg,10kg,100kg
- Release date
- 2020-01-09