ChemicalBook > CAS DataBase List > 2-Benzyl-2-thiopseudourea hydrochloride
2-Benzyl-2-thiopseudourea hydrochloride
- Product Name
- 2-Benzyl-2-thiopseudourea hydrochloride
- CAS No.
- 538-28-3
- Chemical Name
- 2-Benzyl-2-thiopseudourea hydrochloride
- Synonyms
- SBT;btkh;tl944;NSC3206;U-19451A;usafek-2124;WLN: MUYZS1R &GH;2-BENZYL-ISOTHIOUREA;Benzylthiuronium salt;benzyl Isothiourea HCl
- CBNumber
- CB0104986
- Molecular Formula
- C8H11ClN2S
- Formula Weight
- 202.7
- MOL File
- 538-28-3.mol
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2-Benzyl-2-thiopseudourea hydrochloride Property
- Melting point:
- 172-177 °C
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- methanol: soluble1g/10 mL, clear, colorless to very faintly yellow
- form
- powder to crystal
- color
- White
- Water Solubility
- 250 g/L (15 ºC)
- Sensitive
- Hygroscopic
- Merck
- 14,1146
- BRN
- 3656719
- InChI
- InChI=1S/C8H10N2S.ClH/c9-8(10)11-6-7-4-2-1-3-5-7;/h1-5H,6H2,(H3,9,10);1H
- InChIKey
- WJAASTDRAAMYNK-UHFFFAOYSA-N
- SMILES
- C1(C=CC=CC=1)CSC(=N)N.Cl
- CAS DataBase Reference
- 538-28-3(CAS DataBase Reference)
- EPA Substance Registry System
- Carbamimidothioic acid, phenylmethyl ester, monohydrochloride (538-28-3)
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Safety
- Hazard Codes
- T
- Risk Statements
- 25
- Safety Statements
- 36/37/39-45-28A
- RIDADR
- UN 2811 6.1/PG 2
- WGK Germany
- 3
- RTECS
- UM0738000
- TSCA
- Yes
- HazardClass
- 6.1
- PackingGroup
- II
- HS Code
- 29309070
- Toxicity
- LD50 oral in rat: 27mg/kg
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 251038
- Product name
- 2-Benzyl-2-thiopseudourea hydrochloride
- Purity
- 98%
- Packaging
- 100g
- Price
- $118
- Updated
- 2025/07/31
TCI Chemical
- Product number
- B0442
- Product name
- S-Benzylisothiourea Hydrochloride
- Purity
- >99.0%(T)
- Packaging
- 25g
- Price
- $168
- Updated
- 2025/07/31
TRC
- Product number
- B315165
- Product name
- 2-Benzyl-2-thiopseudourea hydrochloride
- Packaging
- 5g
- Price
- $45
- Updated
- 2021/12/16
Frontier Specialty Chemicals
- Product number
- JK106332
- Product name
- 2-Benzyl-2-thiopseudourea hydrochloride
- Purity
- 98%
- Packaging
- 25g
- Price
- $37
- Updated
- 2021/12/16
Oakwood
- Product number
- 099378
- Product name
- S-Benzylisothiourea Hydrochloride
- Purity
- 97%
- Packaging
- 5g
- Price
- $90
- Updated
- 2021/12/16
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2-Benzyl-2-thiopseudourea hydrochloride Chemical Properties,Usage,Production
Chemical Properties
off-white to light beige crystalline powder
Uses
Reagent for cobalt and nickel; identification and separation of carboxylic, sulfinic, and sulfonic acid.
General Description
S-benzylisothiourea analogs (2-benzyl-2-thiopseudourea hydrochloride), as small-molecule inhibitors of indoleamine-2,3-dioxygenase, has been studied.
Safety Profile
Poison by ingestion,intraperitoneal, subcutaneous, and intravenous routes.When heated to decomposition it emits very toxic fumesof HCl, SOx, and NOx.
Synthesis
100-44-7
17356-08-0
538-28-3
GENERAL METHOD: Benzyl chloride (3 mmol) was dissolved with thiourea (3 mmol) in anhydrous ethanol (2 mL) and the reaction was refluxed at 95°C for 2 hours. Upon completion of the reaction, the mixture was cooled to room temperature and stirring was continued for 12 hours. The resulting precipitate was collected by filtration and washed with cold anhydrous ethanol to give the final S-benzylthiourea hydrochloride.
Purification Methods
Crystallise the chloride from 0.2M HCl (2mL/g) or EtOH and it dry in air. [Beilstein 6 III 1600.]
References
[1] Analytical Chemistry, 1987, vol. 59, # 4, p. 562 - 567
[2] Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 8, p. 2426 - 2431
[3] Journal of Pharmaceutical Sciences, 1984, vol. 73, # 3, p. 374 - 377
[4] European Journal of Organic Chemistry, 2002, # 7, p. 1163 - 1174
[5] Chemische Berichte, 1879, vol. 12, p. 575
2-Benzyl-2-thiopseudourea hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Benzyl-2-thiopseudourea hydrochloride manufacturers
Hebei Fengjia New Material Co., Ltd
- Product
- 2-Benzyl-2-thiopseudourea hydrochloride 538-28-3
- Price
- US $5.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 100000
- Release date
- 2024-08-08
Hebei Chuanghai Biotechnology Co., Ltd
- Product
- 2-Benzyl-2-thiopseudourea hydrochloride 538-28-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-22
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- S-Benzylisothiourea Hydrochloride 538-28-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27
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