Piperazinone, 3-(2-thienyl)- (9CI)

Product Name: Piperazinone, 3-(2-thienyl)- (9CI)
CAS No.: 86696-86-8
Chemical Name: Piperazinone, 3-(2-thienyl)- (9CI)
Synonyms: Tenilsetam;3-(2-thienyl)- (9CI);Tenilsetam/Piperazinone;3-(2-Thienyl)-2-piperazinone;3-(2-Thienyl)piperazin-2-one;2-Piperazinone, 3-(2-thienyl)-;Piperazinone, 3-(2-thienyl)- (9CI);Tenilsetam - PAS 997 | CAS 997 | HR 029;Piperazinone, 3-(2-thienyl)- (9CI) USP/EP/BP
CBNumber: CB01052655
Molecular Formula: C8H10N2OS
Formula Weight: 182.24
MOL File: 86696-86-8.mol

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Piperazinone, 3-(2-thienyl)- (9CI) Property

Density: 1.225
InChI: InChI=1S/C8H10N2OS/c11-8-7(9-3-4-10-8)6-2-1-5-12-6/h1-2,5,7,9H,3-4H2,(H,10,11)
InChIKey: BBACKDMGYMXYLE-UHFFFAOYSA-N
SMILES: N1CCNC(C2SC=CC=2)C1=O

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: B587980
Product name: 3-(thiophen-2-yl)piperazin-2-one
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Axon Medchem

Product number: Axon1470
Product name: Tenilsetam-PAS997|CAS997|HR029
Purity: 99%
Packaging: 50mg
Price: $198
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0010538
Product name: 3-(2-THIENYL)-2-PIPERAZINONE
Purity: 95.00%
Packaging: 10MG
Price: $275.1
Updated: 2021/12/16

Matrix Scientific

Product number: 134199
Product name: 3-(Thiophen-2-yl)piperazin-2-one
Purity: 95%+
Packaging: 500mg
Price: $684
Updated: 2021/12/16

Matrix Scientific

Product number: 134199
Product name: 3-(Thiophen-2-yl)piperazin-2-one
Purity: 95%+
Packaging: 2.500g
Price: $1374
Updated: 2021/12/16

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Piperazinone, 3-(2-thienyl)- (9CI) Chemical Properties,Usage,Production

Description

Tenilsetam ((+/-)-3-(2-thienyl)-2-piperazinone; Piperazinone, 3-(2-thienyl)- (9CI)), a cognition-enhancing drug successfully used for the treatment of patients suffering from Alzheimer's disease, when included in the Maillard reaction inhibits protein crosslinking by AGEs in vitro. According to the mechanism proposed, Tenilsetam acts via covalent attachment to glycated proteins, thus blocking the reactive sites for further polymerisation reactions. A beneficial effect of Tenilsetam in Alzheimer's disease could come from the interference with AGE-derived crosslinking of amyloid plaques and a decreased inflammatory response by diminished activation of phagocytosing microglia[1].

References

[1] G Münch. “The cognition-enhancing drug tenilsetam is an inhibitor of protein crosslinking by advanced glycosylation.” Journal of Neural Transmission - Parkinson’s Disease and Dementia Section 8 3 (1994): 193–208.

Piperazinone, 3-(2-thienyl)- (9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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Piperazinone, 3-(2-thienyl)- (9CI) Suppliers

China 11 Europe 1 Switzerland 1 The Netherlands 1 United States 5 USA 1 Global 20

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28806
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

Dideu Industries Group Limited

Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Country: China
ProdList: 22883
Advantage: 58

career henan chemical co

Tel: +86-0371-86658258 +8613203830695
Fax: 0086-371-86658258
Email: factory@coreychem.com
Country: China
ProdList: 29811
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24647
Advantage: 58

Shanghai Haohong Scientific Co., Ltd.

Tel: 400-400-8210725
Email: malulu@leyan.com
Country: China
ProdList: 39990
Advantage: 58

Jilin Chinese Academy of Sciences-yanshen Technology

Tel: +undefined18143011203
Email: info@chemextension.com
Country: China
ProdList: 42056
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Wuhan Han Sheng New Material Technology Co.，Ltd

Tel: +8617798174412
Email: admin01@hsnm.com.cn
Country: China
ProdList: 2097
Advantage: 58

Zhengzhou Anbu Chem Co.,Ltd

Tel: +86-0371-88006763; +8615988602810
Email: sales@anbuchem.com
Country: China
ProdList: 2998
Advantage: 58

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View Lastest Price from Piperazinone, 3-(2-thienyl)- (9CI) manufacturers

Dideu Industries Group Limited

Product: Piperazinone, 3-(2-thienyl)- (9CI) 86696-86-8
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-07-06

Career Henan Chemical Co

Product: Piperazinone, 3-(2-thienyl)- (9CI) 86696-86-8
Price: US $1.00/g
Min. Order: 1g
Purity: 99.0%
Supply Ability: 100kg
Release date: 2020-01-09

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