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Bapotulimab

Product Name
Bapotulimab
CAS No.
2359413-58-2
Chemical Name
Bapotulimab
Synonyms
Bapotulimab;Bapotulimab (anti-ILDR2);Research Grade Bapotulimab;Research Grade Bapotulimab (DHB96301)
CBNumber
CB010617007
Formula Weight
0
MOL File
Mol file
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Bapotulimab Property

form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

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Bapotulimab Chemical Properties,Usage,Production

Uses

Bapotulimab (BAY-1905254) is a fully human IgG2 antibody targeting immunoglobulin-like domain containing receptor 2 (ILDR2). Bapotulimab has antitumor and immunosuppressive effects[1].

in vivo

Bapotulimab (BAY-1905254; 10 mg/kg; i.p.; on days 1 and 4) shows significantly increased antigen-specific T-cell proliferation and cytotoxicity[1].

Animal Model:8- to 12-week-old CD45.1-expressing C57BL/6 wild-type mice injected with OT-I transgenic T cells[1]
Dosage:10 mg/kg
Administration: i.p.; on days 1 and 4
Result:Showed significantly increased antigen-specific T-cell proliferation and cytotoxicity.

References

[1] Julia Huetter, et al. Characterization of BAY 1905254, an Immune Checkpoint Inhibitor Targeting the Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2). Cancer Immunol Res. 2020 Jul;8(7):895-911. DOI:10.1158/2326-6066.CIR-19-0321

Bapotulimab Preparation Products And Raw materials

Raw materials

Preparation Products

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Bapotulimab Suppliers

Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
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QQ:3008007432
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3008007409@qq.com
Country
China
ProdList
71826
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60
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
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QQ:2853530913
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2853530910@QQ.com
Country
China
ProdList
8000
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62
Guangzhou Hongyuan Chemical Co.,Ltd
Tel
15817493340
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981810490@qq.com
Country
China
ProdList
1566
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58
Wuhan Chemstan Biotechnology Co., Ltd.
Tel
027-65317797 15926423062
Fax
QQ:422450190
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422450190@qq.com
Country
China
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10308
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Biolab Reagents
Tel
027-65279366 18108604356
Email
products@biolabreagent.com
Country
China
ProdList
9868
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Wanxin Biotechnology (Jiaxing) Co., LTD
Tel
0573-83568680 18057391398
Email
3956524501@qq.com
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China
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Atagenix Laboratories
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027-87008169 17762441161
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info@atagenix.com
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China
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AntibodySystem Laboratories SAS
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33175446423
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support@antibodysystem.com
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China
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Selleck Chemicals
Tel
400-668-6834
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info@selleck.cn
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China
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2359413-58-2, BapotulimabRelated Search:


  • Bapotulimab
  • Research Grade Bapotulimab (DHB96301)
  • Research Grade Bapotulimab
  • Bapotulimab (anti-ILDR2)
  • 2359413-58-2