ChemicalBook > CAS DataBase List > A20FMDV2
A20FMDV2
- Product Name
- A20FMDV2
- CAS No.
- 932699-03-1
- Chemical Name
- A20FMDV2
- Synonyms
- A20FMDV2;L-Threonine, L-asparaginyl-L-alanyl-L-valyl-L-prolyl-L-asparaginyl-L-leucyl-L-arginylglycyl-L-α-aspartyl-L-leucyl-L-glutaminyl-L-valyl-L-leucyl-L-alanyl-L-glutaminyl-L-lysyl-L-valyl-L-alanyl-L-arginyl-
- CBNumber
- CB010640380
- Molecular Formula
- C93H163N31O28
- Formula Weight
- 2163.52
- MOL File
- 932699-03-1.mol
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A20FMDV2 Property
- Density
- 1.47±0.1 g/cm3(Predicted)
- form
- Solid
- color
- White to off-white
- Sequence
- Asn-Ala-Val-Pro-Asn-Leu-Arg-Gly-Asp-Leu-Gln-Val-Leu-Ala-Gln-Lys-Val-Ala-Arg-Thr
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A20FMDV2 Chemical Properties,Usage,Production
Uses
A20FMDV2 is a selective αvβ6 integrin inhibitor (IC50: 3 nM), with an activity 1,000-fold more selective for αvβ6 than for other RGD-directed integrins (αvβ3, αvβ5, and α5β1). A20FMDV2 can be derived from the foot-and-mouth disease virus. A20FMDV2 can be radiolabeled for the PET imaging of αvβ6 integrin-positive tumors[1].
References
[1] Hausner SH, et al. Use of a peptide derived from foot-and-mouth disease virus for the noninvasive imaging of human cancer: generation and evaluation of 4-[18F]fluorobenzoyl A20FMDV2 for in vivo imaging of integrin alphavbeta6 expression with positron emission tomography. Cancer Res. 2007 Aug 15;67(16):7833-40. DOI:10.1158/0008-5472.CAN-07-1026
A20FMDV2 Preparation Products And Raw materials
Raw materials
Preparation Products
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932699-03-1, A20FMDV2Related Search:
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