Val-cit-PAB-OH

Product Name: Val-cit-PAB-OH
CAS No.: 159857-79-1
Chemical Name: Val-cit-PAB-OH
Synonyms: H-Val-Cit-PAB-OH;(S)-2-((S)-2-amino-3-methylbutanamido)-N-(4-(hydroxymethyl)phenyl)-5-ureidopentanamide;EOS-61316;al-Cit-PAB-OH;H-Val-Cit-PAB;Val-cit-PAB-OH;(D)-VAL-CIT-PAB;NH2-Val-Cit-PAB;2-(4-(((2,6-dimethylbenzoyl)oxy)methyl)phenyl)aceticacid;L-Valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide
CBNumber: CB92715206
Molecular Formula: C18H29N5O4
Formula Weight: 379.45
MOL File: 159857-79-1.mol

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Val-cit-PAB-OH Property

Melting point:: 168 °C(dec.)
Boiling point:: 715.0±60.0 °C(Predicted)
Density: 1.243±0.06 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
solubility: DMF: 10 mg/ml; DMSO: 10 mg/ml; PBS (pH 7.2): 1 mg/ml
form: powder to crystal
pka: 13.75±0.46(Predicted)
color: White to Almost white

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Safety

HS Code: 2924.29.7790

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: V0155
Product name: Val-Cit-PAB-OH
Packaging: 25MG
Price: $160
Updated: 2024/03/01

TCI Chemical

Product number: V0155
Product name: Val-Cit-PAB-OH
Packaging: 100MG
Price: $482
Updated: 2024/03/01

TRC

Product number: V091545
Product name: Val-cit-PAB-OH
Packaging: 100mg
Price: $580
Updated: 2021/12/16

BroadPharm

Product number: BP-23218
Product name: Val-Cit-PAB-OH
Purity: 95%
Packaging: 500mg
Price: $290
Updated: 2021/12/16

ChemScene

Product number: CS-5171
Product name: Val-cit-PAB-OH
Purity: 99.35%
Packaging: 250mg
Price: $157
Updated: 2021/12/16

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Val-cit-PAB-OH Chemical Properties,Usage,Production

Description

Val-Cit-PAB-OH is a peptide cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). The Val-Cit will specifically be cleaved by Cathepsin B.

Uses

Val-cit-PAB-OH acts as a reagent in the preparation of cell-penetrating peptidic GRP78 ligand for tumor cell-specific prodrug therapy, preparation of monomethylvaline derivative conjugates with ligands and antibodies for cancer treatment.

Val-cit-PAB-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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Val-cit-PAB-OH Suppliers

China 195 India 4 Japan 1 United States 14 Global 214

Chemyouth Life Science（Suzhou）Co.,Ltd

Tel: 0512-52112288 13752065514
Email: jianwei@chemyouth.com
Country: China
ProdList: 49
Advantage: 58

Shenzhen Yuzhong Pharmaceutical Technology Co., Ltd.

Tel: 13414494621
Fax: qq: 30307604
Email: chenchao02lzu@126.com
Country: China
ProdList: 122
Advantage: 58

Heze Development Zone chuangli Chemical Co., Ltd.

Tel: +86-530-529 6766，+86-15666160102 15666160102
Fax: 0530-529 6766
Email: info@chuangli-chem.com
Country: China
ProdList: 896
Advantage: 55

Hangzhou Sinoda Pharmaceutical Technology Co. LTD

Tel: 0571-87213919 17306812703
Email: 3007955328@qq.com
Country: China
ProdList: 6659
Advantage: 58

Hygeia (Chengdu) pharmaceutical technique Co., Ltd

Tel: 028-84502008 13568869383
Fax: 028-66476329
Email: sales@hygeiapharm.com
Country: China
ProdList: 299
Advantage: 55

Zhongke Huayao (Jiangsu) Biotechnology Co., Ltd

Tel: 13770887460
Email: wenxi@jszkhy.com
Country: China
ProdList: 1351
Advantage: 58

Beijing InnoChem Science & Technology Co., Ltd.

Tel: 15652467323 15652467323
Email: sales@inno-chem.com.cn
Country: China
ProdList: 8293
Advantage: 58

Wuxi Donghe Pharmaceutical Technology Co., Ltd.

Tel: 63313187 15358055255
Fax: QQ：63313187
Email: 63313187@qq.com
Country: China
ProdList: 1987
Advantage: 58

Suzhou Sino Rare Chemical Co., Ltd.

Tel: 512-62857507
Email: sales@sinorarechem.com
Country: China
ProdList: 523
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

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View Lastest Price from Val-cit-PAB-OH manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Val-Cit-PAB-OH 159857-79-1
Price: US $0.00/g
Min. Order: 5g
Purity: >95.00%
Supply Ability: 5g
Release date: 2024-03-29

Henan Aochuang Chemical Co.,Ltd.

Product: Val-cit-PAB-OH 159857-79-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-13

Career Henan Chemical Co

Product: Val-cit-PAB-OH 159857-79-1
Price: US $1.00/g
Min. Order: 1g
Purity: ≥98%
Supply Ability: g/kg/Ton
Release date: 2020-03-05

159857-79-1, Val-cit-PAB-OHRelated Search:

Peptide synthesis ALA-SER-THR-THR-THR-ASN-TYR-THR ACETATE Peptide impurity peptide CRO OGP (Ostegenic Growth Peptide) Peptide phosphorylation marker Peptide fluorescent modification GMP peptide CMO L-Threonine, L-asparaginyl-L-alanyl-L-valyl-L-prolyl-L-asparaginyl-L-leucyl-L-arginylglycyl-L-α-aspartyl-L-leucyl-L-glutaminyl-L-valyl-L-leucyl-L-alanyl-L-glutaminyl-L-lysyl-L-valyl-L-alanyl-L-arginyl- FMoc-Val-Cit-PAB-PNP pyrene-2,7-diyldiboronic acid Fmoc-Val-Cit-OH FMoc-Val-Cit-PAB MC-Val-Cit-PAB

(S)-2-((R)-2-amino-3-methylbutanamido)-N-(4-(hydroxymethyl)phenyl)-5-ureidopentanamide

EOS-61316

(S)-2-((S)-2-amino-3-methylbutanamido)-N-(4-(hydroxymethyl)phenyl)-5-ureidopentanamide

L-Ornithinamide, L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-

Val-cit-PAB-OH

L-Valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide

NH2-Val-Cit-PAB

(D)-VAL-CIT-PAB

al-Cit-PAB-OH

H-Val-Cit-PAB-OH

2-(4-(((2,6-dimethylbenzoyl)oxy)methyl)phenyl)aceticacid

H-Val-Cit-PAB

(2S)-2-[[(2S)-2-amino-3-methyl-butanoyl]amino]-N-[4-(hydroxymethyl)phenyl]-5-ureido-pentanamide

159857-79-1

Linker

ADC LINKER

ADCs

ADC-Linkers