FMoc-Val-Cit-PAB

Uses

Product Name: FMoc-Val-Cit-PAB
CAS No.: 159858-22-7
Chemical Name: FMoc-Val-Cit-PAB
Synonyms: Fmoc-Val-Cit-PAB-OH;(9H-fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate;FMoc-Val-Cit-PAB;Fomc-Val-Cit-PAB;TrastuzumabImpurity2;Fmoc-L-Val-Cit-PAB-OH;Fmoc-val-citrulline-para-aminobenzyl-OH;Trastuzumab Impurity 2 (Fmoc-Val-Cit-PAB-OH);4-(N-((9H-fluoren-9-yl)methoxycarbonyl)-L-valinyl-D-citrullinamido)benzyl alcohol;N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide
CBNumber: CB02730901
Molecular Formula: C33H39N5O6
Formula Weight: 601.69
MOL File: 159858-22-7.mol

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FMoc-Val-Cit-PAB Property

Melting point:: 204 °C(dec.)
Boiling point:: 914.2±65.0 °C(Predicted)
Density: 1.276±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Store in freezer, under -20°C
form: powder to crystal
pka: 10.63±0.46(Predicted)
color: White to Almost white
CAS DataBase Reference: 159858-22-7

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Safety

HS Code: 2924.29.7790

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TCI Chemical

Product number: F1223
Product name: Fmoc-Val-Cit-PAB-OH
Packaging: 25MG
Price: $16
Updated: 2024/03/01

TCI Chemical

Product number: F1223
Product name: Fmoc-Val-Cit-PAB-OH
Packaging: 100MG
Price: $39
Updated: 2024/03/01

AK Scientific

Product number: 2998DP
Product name: Fmoc-Val-Cit-PAB
Packaging: 25mg
Price: $259
Updated: 2021/12/16

ChemScene

Product number: CS-5170
Product name: Fmoc-Val-Cit-PAB
Purity: 97.15%
Packaging: 250mg
Price: $300
Updated: 2021/12/16

Iris Biotech GmbH

Product number: ADC1030
Product name: Fmoc-Val-Cit-PAB
Packaging: 250mg
Price: $303.75
Updated: 2021/12/16

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FMoc-Val-Cit-PAB Chemical Properties,Usage,Production

Uses

Fmoc-Val-Cit-PAB is a commonly used bridge for a degradable antibody-conjugated drug (ADC).

Description

Fmoc-Val-Cit-PAB-OH is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. Fmoc can be deprotected under basic condition.

FMoc-Val-Cit-PAB Preparation Products And Raw materials

Raw materials

Preparation Products

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FMoc-Val-Cit-PAB Suppliers

Americas 1 China 207 Europe 1 India 4 Japan 1 United States 7 Global 221

Shenzhen Yuzhong Pharmaceutical Technology Co., Ltd.

Tel: 13414494621
Fax: qq: 30307604
Email: chenchao02lzu@126.com
Country: China
ProdList: 122
Advantage: 58

Zhenjiang Renzhi Biotechnology Co., Ltd.

Tel: 18762678737
Email: 751546636@qq.com
Country: China
ProdList: 38
Advantage: 58

Changzhou PBpharmaceutical R&D Co.,Ltd

Tel: 0519-83990708
Fax: 0519-83990708
Email: lxy2046@yeah.net
Country: China
ProdList: 476
Advantage: 55

Hangzhou Sinoda Pharmaceutical Technology Co. LTD

Tel: 0571-87213919 17306812703
Email: 3007955328@qq.com
Country: China
ProdList: 6659
Advantage: 58

YJ Pharma

Tel: 13962794339 13962794339
Email: 3686954964@qq.com
Country: China
ProdList: 168
Advantage: 58

Shanghai Send Pharmaceutical Technology Co., Ltd.

Tel: +86-021-50266790 Q2816483246
Fax: 021-50266790
Email: sale@shsendpharm.com
Country: China
ProdList: 196
Advantage: 50

Shanghai Yanfen Biochemical Technology Co.,LTD

Tel: 13611955358 13611955358
Email: yanfen2024@126.com
Country: China
ProdList: 854
Advantage: 58

Daicel Chiral Technologies (China)CO.,LTD

Tel: 021-50460086-9 15921403865
Fax: +86-21-50462321
Email: han_yajun@dctc.daicel.com
Country: China
ProdList: 7195
Advantage: 65

Chengdu Pukang Biotechnology Co., Ltd

Tel: 028-82550498 19102685862
Fax: 086-28-82550468
Email: sales@pu-kang.com
Country: China
ProdList: 485
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Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9458
Advantage: 58

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View Lastest Price from FMoc-Val-Cit-PAB manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: FMoc-Val-Cit-PAB 159858-22-7
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-05-24

Xian confluore Biological Technology Co., Ltd.

Product: Fmoc-Val-Cit-PAB-OH 159858-22-7
Price: US $0.00/g
Min. Order: 10g
Purity: >95.00%
Supply Ability: 10g
Release date: 2024-03-29

Henan Aochuang Chemical Co.,Ltd.

Product: FMoc-Val-Cit-PAB 159858-22-7
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-13

159858-22-7, FMoc-Val-Cit-PABRelated Search:

FMoc-Val-Cit-PAB-PNP Val-cit-PAB-OH pyrene-2,7-diyldiboronic acid Fmoc-Val-Cit-OH MC-Val-Cit-PAB

FMoc-Val-Cit-PAB

Fmoc-Val-Cit-PAB-OH

(9H-fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate

L-Ornithinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-

(9H-fluoren-9-yl)methyl((S)-1-((())-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate

(9H-fluoren-9-yl)methyl N-[(1S)-1-{[(1S)-4-(carbamoylamino)-1-{[4-(hydroxymethyl)phenyl]carbamoyl}butyl]carbamoyl}-2-methylpropyl]carbamate

Fmoc-val-citrulline-para-aminobenzyl-OH

(9H-fluoren-9-yl)methyl ((2S)-1-((1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate

4-(N-((9H-fluoren-9-yl)methoxycarbonyl)-L-valinyl-D-citrullinamido)benzyl alcohol

TrastuzumabImpurity2

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide

9H-fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbam

9H-fluoren-9-ylmethyl N-[(2S)-1-[[(2S)-5-(carbamoylamino)-1-[4-(hydroxymethyl)anilino]-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate

Trastuzumab Impurity 2 (Fmoc-Val-Cit-PAB-OH)

Fmoc-L-Val-Cit-PAB-OH

Fomc-Val-Cit-PAB

159858-22-7

159858-22-8

1959858-22-7

ADCs

ADC Linker

ADC-Linker

ADC-Linkers