FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID

Product Name: FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID
CAS No.: 557756-85-1
Chemical Name: FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID
Synonyms: FMoc-NH-PEG4-CH2CH2COOH;1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid;Fmoc-NH-PEG4-COOH;Fmoc-NH-(PEG)3-COOH;Fmoc-PEG4-propionic acid;3-[2-[2-[2-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propionic acid;Fmoc-PEG4-OH;FMOC-15-AMINO-4;FmocNH-PEG5-acid;Fmoc-NH-PEG4c-COOH
CBNumber: CB5201606
Molecular Formula: C26H33NO8
Formula Weight: 487.54
MOL File: 557756-85-1.mol

More

Less

FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID Property

Boiling point:: 682.1±55.0 °C(Predicted)
Density: 1.219
storage temp.: -20°C
solubility: Soluble in DMSO, DCM, DMF
form: solid or viscous liquid
pka: 4.28±0.10(Predicted)
color: Colorless to light yellow
InChI: InChI=1S/C26H33NO8/c28-25(29)9-11-31-13-15-33-17-18-34-16-14-32-12-10-27-26(30)35-19-24-22-7-3-1-5-20(22)21-6-2-4-8-23(21)24/h1-8,24H,9-19H2,(H,27,30)(H,28,29)
InChIKey: NUHRPLKTAAVHCZ-UHFFFAOYSA-N
SMILES: C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)(=O)NCCOCCOCCOCCOCCC(O)=O

More

Less

Safety

Safety Statements: 24/25
HS Code: 29225090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.51035
Product name: Fmoc-NH-(PEG)₃-COOH (16 atoms)
Purity: Novabiochem®
Packaging: 1 g
Price: $587
Updated: 2025/07/31

ChemScene

Product number: CS-W000434
Product name: Fmoc-NH-PEG4-CH2CH2COOH
Purity: 98.75%
Packaging: 250mg
Price: $53
Updated: 2021/12/16

Activate Scientific

Product number: AS115286
Product name: FmocNH-PEG4-CH2CH2COOH
Purity: 98+%
Packaging: 250mg
Price: $98
Updated: 2021/12/16

dPEG

Product number: 10213
Product name: Fmoc-N-amido-dPEG??-acid
Packaging: 100mg
Price: $100
Updated: 2021/12/16

BroadPharm

Product number: BP-20989
Product name: Fmoc-N-amido-PEG4-acid
Purity: 98%
Packaging: 500mg
Price: $120
Updated: 2021/12/16

More

Less

FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID Chemical Properties,Usage,Production

Description

Fmoc-N-amido-PEG4-acid is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Chemical Properties

Yellow oil

Uses

Fmoc-NH-PEG4-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG4-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

reaction suitability

reaction type: Pegylations
reagent type: cross-linking reagent

IC 50

Cleavable Linker; PEGs

References

[1] Cai P, et al. Synthesis of C3-Alkylated Indoles on DNA via Indolyl Alcohol Formation Followed by Metal-FreeTransfer Hydrogenation. Org Lett. 2019 Aug 14. DOI:10.1021/acs.orglett.9b02132

FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID Suppliers

China 165 France 1 India 2 United Kingdom 1 United States 19 Global 188

Guangzhou Hongyuan Chemical Co.,Ltd

Tel: 15817493340
Email: 981810490@qq.com
Country: China
ProdList: 1566
Advantage: 58

Biomatrik (Jiaxing) Inc.

Tel: 573-573-82623377 18967387295
Fax: +86 (573) 8262-3317
Email: sales@biomatrik.cn
Country: China
ProdList: 70
Advantage: 61

Shanghai Yanfen Biochemical Technology Co.,LTD

Tel: 17721070236 15002190549;
Email: yanfen2023@126.com
Country: China
ProdList: 1837
Advantage: 58

Jilin Chinese Academy of Sciences-yanshen Technology

Tel: 18143011203
Email: ET-market@chemextension.com
Country: China
ProdList: 32034
Advantage: 58

Wanxin Biotechnology (Jiaxing) Co., LTD

Tel: 0573-83568680 18057391398
Email: 3956524501@qq.com
Country: China
ProdList: 1442
Advantage: 58

Changsha Morning Shine Co., Ltd.

Tel: 189-75832125 13397510867
Email: BD@csmspharm.com
Country: China
ProdList: 399
Advantage: 58

Zhejiang Rui 'ao Biological Technology Co.,LTD.

Tel: +86-573-82087565 15757883359
Email: yan@ruiaochem.cn
Country: China
ProdList: 640
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Alabiochem Tech.Co., Ltd.

Tel: 512-58900862 400-0707518
Fax: 0086-512-56765862
Email: sales@alabiochem.com
Country: China
ProdList: 970
Advantage: 59

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

More

Less

View Lastest Price from FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID manufacturers

LAURENT

Product: Fmoc-NH-PEG4-CH2CH2COOH 557756-85-1
Price: US $36.58/g
Min. Order: 10g
Purity: 98%
Supply Ability: 300kg
Release date: 2025-11-17

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid 557756-85-1
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
Release date: 2025-09-12

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: Fmoc-NH-PEG4-CH2CH2COOH 557756-85-1
Price: US $2.00-6.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-08-06

557756-85-1, FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACIDRelated Search:

Bis-PE21- NHS ester 1-AMINO-3,6,9-TRIOXAUNDECANYL-11-OL Bis(NHS)PEG5 m-PEG8-NHS ester alpha-MaleiMidopropionyl-oMega-succiniMidyl-8(ethylene glycol) FMOC-18-AMINO-4,7,10,13,16-PENTAOXAOCTADECANOIC ACID 2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL FMoc-NH-PEG9-CH2CH2COOH 5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid,1-(9-fluren-9-ylmethyl)ester 3,6,9,12,15,18-Hexaoxanonadecane-1-thiol 5,8,11-Trioxa-2-azatridecanoic,13-amino,1,1-dimethylethyl ester FmocNH-PEG4-t-butyl acetate FmocNH-PEG5-t-butly ester 5,8,11,14-Tetraoxa-2-azahexadecanedioic acid MPEG3-NHS 1-AMinooctaethylene Glycol (+)-Biotin-PEG4-Hydrazide FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID

FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID

FMoc-15-aMino-4,7,10,13-tetraoxapentadecacanoic acid

FMoc-NH-PEG4-CH2CH2COOH

3-[2-[2-[2-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propionic acid

5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid 1-(9H-fluoren-9-ylmethyl) ester

3-[2-[2-[2-[2-(9H-fluoren-9-ylMethoxycarbonylaMino)ethoxy]ethoxy]ethoxy]ethoxy]propanoicacid

1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid

FmocNH-PEG5-acid

Fmoc-N-amido-PEG4-acid

Fmoc-PEG4- CH2CH2COOH

Fmoc-PEG4-propionic acid

Fmoc-15-amino-4,7,10,13-tetraoxapentadecanoic acid≥ 97% (HPLC)

Fmoc-NH-(PEG)3-COOH

1-(9H-Fluoren-9-yl)-3-oxo-2,7,1,13,16-pentaoxa-4-azanonadecan-19-oic acid

Fmoc-NH-PEG4-COOH

Fmoc-PEG4-OH 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid

Fmoc-N-amido-dPEG(R)4-acid

15-(Fmoc-amino)-4,7,10,13-tetraoxapentadecanoic Acid

1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3,6,9,12-tetraoxapentadecan-15-oic acid

Fmoc-NH-PEG4c-COOH

FMOC-AMINO-PEG4-PROPANOIC ACID

Moc-NH-PEG3-CH2CH2COOH

13-TETRAOXAPENTADECANOIC ACID

FMOC-15-AMINO-4

Fmoc-NH-PEG4-CH2CH2COOH/5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester

FmocNH-PEG4-C2-COOH

Fmoc-N-amido-PEG4-propionic acid

Fmoc-PEG4-OH

Fmoc-NH-(PEG)4-CH2CH2COOH - 1 g

Fmoc-NH-(PEG)?-COOH (16 atoms)

Fmoc-N-amido-dPEG?4-acid

Fmoc-N-amido-dPEG??-acid (QBD-10213)

Fmoc-NH-dPEG?4-propionic acid

Fmoc-NH-PEG4-Propionic Acid

557756-85-1

C26H33NO8

peg