ChemicalBook > CAS DataBase List > FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID

FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID

Product Name
FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID
CAS No.
557756-85-1
Chemical Name
FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID
Synonyms
FMoc-NH-PEG4-CH2CH2COOH;1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid;Fmoc-NH-PEG4-COOH;Fmoc-NH-(PEG)3-COOH;Fmoc-PEG4-propionic acid;3-[2-[2-[2-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propionic acid;Fmoc-PEG4-OH;FmocNH-PEG4-PA;FMOC-15-AMINO-4;FmocNH-PEG5-acid
CBNumber
CB5201606
Molecular Formula
C26H33NO8
Formula Weight
487.54
MOL File
557756-85-1.mol
More
Less

FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID Property

Boiling point:
682.1±55.0 °C(Predicted)
Density 
1.219
storage temp. 
-20°C
solubility 
Soluble in DMSO, DCM, DMF
form 
solid or viscous liquid
pka
4.28±0.10(Predicted)
color 
Colorless to light yellow
Major Application
peptide synthesis
InChI
InChI=1S/C26H33NO8/c28-25(29)9-11-31-13-15-33-17-18-34-16-14-32-12-10-27-26(30)35-19-24-22-7-3-1-5-20(22)21-6-2-4-8-23(21)24/h1-8,24H,9-19H2,(H,27,30)(H,28,29)
InChIKey
NUHRPLKTAAVHCZ-UHFFFAOYSA-N
SMILES
C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)(=O)NCCOCCOCCOCCOCCC(O)=O
More
Less

Safety

Safety Statements 
24/25
WGK Germany 
WGK 2
HS Code 
29225090
Storage Class
11 - Combustible Solids
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.51035
Product name
Fmoc-NH-(PEG)₃-COOH (16 atoms)
Purity
Novabiochem<SUP>&#174;</SUP>
Packaging
1 g
Price
$625
Updated
2026/04/30
BroadPharm
Product number
bp-20989
Product name
Fmoc-N-amido-PEG4-acid
Purity
98%
Packaging
250MG
Price
$80
Updated
2026/05/24
BroadPharm
Product number
bp-20989
Product name
Fmoc-N-amido-PEG4-acid
Purity
98%
Packaging
500MG
Price
$120
Updated
2026/05/24
BroadPharm
Product number
bp-20989
Product name
Fmoc-N-amido-PEG4-acid
Purity
98%
Packaging
1G
Price
$175
Updated
2026/05/24
BroadPharm
Product number
bp-20989
Product name
Fmoc-N-amido-PEG4-acid
Purity
98%
Packaging
5G
Price
$570
Updated
2026/05/24
More
Less

FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID Chemical Properties,Usage,Production

Description

Fmoc-N-amido-PEG4-acid is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Chemical Properties

Yellow oil

Uses

Fmoc-NH-PEG4-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG4-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

reaction suitability

reaction type: Pegylations
reagent type: cross-linking reagent

IC 50

Cleavable Linker; PEGs

References

[1] Cai P, et al. Synthesis of C3-Alkylated Indoles on DNA via Indolyl Alcohol Formation Followed by Metal-FreeTransfer Hydrogenation. Org Lett. 2019 Aug 14. DOI:10.1021/acs.orglett.9b02132

FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID Suppliers

Guangzhou Hongyuan Chemical Co.,Ltd
Tel
15817493340
Email
981810490@qq.com
Country
China
ProdList
1566
Advantage
58
Shanghai Yanfen Biochemical Technology Co.,LTD
Tel
13611955358 15002190549
Email
yanfen2023@126.com
Country
China
ProdList
1780
Advantage
58
Jilin Chinese Academy of Sciences-yanshen Technology
Tel
18143011203
Email
ET-market@chemextension.com
Country
China
ProdList
36878
Advantage
58
Zhejiang Rui 'ao Biological Technology Co.,LTD.
Tel
82087565 15757883359
Email
yan@ruiaochem.cn
Country
China
ProdList
677
Advantage
58
Biomatrik (Jiaxing) Inc.
Tel
0573-82623377 18967387295
Fax
+86 (573) 8262-3317
Email
sales@biomatrik.cn
Country
China
ProdList
50
Advantage
61
Shandong Zhengtuo Pharmaceutical Technology Co., Ltd.
Tel
15666908650
Email
meijia.sun@zheng-tuo.com
Country
China
ProdList
126
Advantage
58
Suzhou Highfine Biotech Co., Ltd
Tel
0512-68311833 13771732418
Email
chenmengqi@highfine.com
Country
China
ProdList
1722
Advantage
58
Yangzhou Jide Kangrui Biotechnology Co., Ltd.
Tel
15029750239
Email
1002921772@qq.com
Country
China
ProdList
371
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94642
Advantage
76
Alabiochem Tech.Co., Ltd.
Tel
512-58900862 400-0707518
Fax
0086-512-56765862
Email
sales@alabiochem.com
Country
China
ProdList
936
Advantage
59
More
Less

View Lastest Price from FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.
Product
Fmoc-N-amido-PEG4-PA 557756-85-1
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1g/bottle, 10g/bottle, 100g/bottle
Release date
2026-02-06
LAURENT
Product
Fmoc-NH-PEG4-CH2CH2COOH 557756-85-1
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
300kg
Release date
2026-01-28
XIAMEN SINOPEG BIOTECH CO., LTD.
Product
1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid 557756-85-1
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1g/bottle, 10g/bottle, 100g/bottle
Release date
2025-09-12

557756-85-1, FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACIDRelated Search:


  • FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID
  • FMoc-15-aMino-4,7,10,13-tetraoxapentadecacanoic acid
  • FMoc-NH-PEG4-CH2CH2COOH
  • 3-[2-[2-[2-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propionic acid
  • 5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid 1-(9H-fluoren-9-ylmethyl) ester
  • 3-[2-[2-[2-[2-(9H-fluoren-9-ylMethoxycarbonylaMino)ethoxy]ethoxy]ethoxy]ethoxy]propanoicacid
  • 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid
  • FmocNH-PEG5-acid
  • Fmoc-N-amido-PEG4-acid
  • Fmoc-PEG4- CH2CH2COOH
  • Fmoc-PEG4-propionic acid
  • Fmoc-15-amino-4,7,10,13-tetraoxapentadecanoic acid≥ 97% (HPLC)
  • Fmoc-NH-(PEG)3-COOH
  • 1-(9H-Fluoren-9-yl)-3-oxo-2,7,1,13,16-pentaoxa-4-azanonadecan-19-oic acid
  • Fmoc-NH-PEG4-COOH
  • Fmoc-PEG4-OH 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid
  • Fmoc-N-amido-dPEG(R)4-acid
  • 15-(Fmoc-amino)-4,7,10,13-tetraoxapentadecanoic Acid
  • 1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3,6,9,12-tetraoxapentadecan-15-oic acid
  • Fmoc-NH-PEG4c-COOH
  • FMOC-AMINO-PEG4-PROPANOIC ACID
  • Moc-NH-PEG3-CH2CH2COOH
  • 13-TETRAOXAPENTADECANOIC ACID
  • FMOC-15-AMINO-4
  • Fmoc-NH-PEG4-CH2CH2COOH/5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester
  • FmocNH-PEG4-C2-COOH
  • Fmoc-N-amido-PEG4-propionic acid
  • Fmoc-PEG4-OH
  • Fmoc-NH-(PEG)4-CH2CH2COOH - 1 g
  • Fmoc-NH-(PEG)?-COOH (16 atoms)
  • Fmoc-N-amido-dPEG<sup>?</sup><sub>4</sub>-acid
  • Fmoc-N-amido-dPEG??-acid (QBD-10213)
  • Fmoc-NH-dPEG?4-propionic acid
  • Fmoc-NH-PEG4-Propionic Acid
  • Fmoc-NH-PEG4-CH2CH2COOH (HQ)
  • Fmoc-N-amido-PEG4-PA
  • FmocNH-PEG4-PA
  • 557756-85-1
  • C26H33NO8
  • peg