(+)-Biotin-PEG4-Hydrazide

Product Name: (+)-Biotin-PEG4-Hydrazide
CAS No.: 756525-97-0
Chemical Name: (+)-Biotin-PEG4-Hydrazide
Synonyms: 4-hydrazide;Biotin-dPEG®Biotin-PEG4-hydrazide;Biotin-dPEG??-hydrazide;Biotin-dPEG(R)4-hydrazide;(+)-Biotin-PEG4-Hydrazide;(+)-biotin-peg4-hydrazide;Biotin-PEG4-Propinonic hydrazide;Biotin-dPEG??-hydrazide (QBD-10219);Biotin-dPEG^?₄-hydrazide
CBNumber: CB73155023
Molecular Formula: C21H39N5O7S
Formula Weight: 505.63
MOL File: 756525-97-0.mol

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(+)-Biotin-PEG4-Hydrazide Property

Boiling point:: 825.5±65.0 °C(Predicted)
Density: 1.201±0.06 g/cm3(Predicted)
storage temp.: -20°C
form: solid or viscous liquid
pka: 12.82±0.35(Predicted)
color: White to Light yellow

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Safety

HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: QBD10219
Product name: Biotin-dPEG®4-hydrazide
Packaging: 50MG
Price: $633
Updated: 2025/07/31

Sigma-Aldrich

Product number: QBD10219
Product name: Biotin-dPEG®4-hydrazide
Packaging: 1000MG
Price: $1600
Updated: 2025/07/31

TCI Chemical

Product number: B5578
Product name: Biotin-PEG4-Hydrazide
Purity: >94.0%(HPLC)
Packaging: 10mg
Price: $80
Updated: 2025/07/31

TCI Chemical

Product number: B5578
Product name: Biotin-PEG4-Hydrazide
Purity: >94.0%(HPLC)
Packaging: 50mg
Price: $235
Updated: 2025/07/31

BroadPharm

Product number: BP-24269
Product name: Biotin-PEG4-Hydrazide
Purity: 98%
Packaging: 25mg
Price: $240
Updated: 2021/12/16

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(+)-Biotin-PEG4-Hydrazide Chemical Properties,Usage,Production

Description

Biotin-PEG4-hydrazide is a biotinylation reagent that can be used to label glycoproteins, carbohydrate-containing compounds that have oxidizable sugars or aldehydes. Hydrazine moiety reacts with an aldehyde to form semi-permanent hydrazone bonds. The hydrophilic PEG arm imparts water solubility that is transferred to the biotinylated molecule.

Uses

Biotin-PEG4-hydrazide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

reaction suitability

reagent type: cross-linking reagent
reaction type: Biotinylations
reactivity: carbonyl reactive

IC 50

PEGs

References

[1] Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521. DOI:10.1038/nchembio.2329

(+)-Biotin-PEG4-Hydrazide Preparation Products And Raw materials

Raw materials

Preparation Products

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(+)-Biotin-PEG4-Hydrazide Suppliers

Americas 1 China 47 Europe 1 India 1 Japan 1 United Kingdom 1 United States 6 Global 58

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
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Chengdu Pukang Biotechnology Co., Ltd

Tel: +86-028-82550498 +86-19102685862
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TOKYO CHEMICAL INDUSTRY CO., LTD.

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Country: Europe
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Sigma-Aldrich

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Tongling HengYou Biotechnology Co., Ltd.

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Shanghai YuanYe Biotechnology Co., Ltd.

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Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
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Country: China
ProdList: 4952
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View Lastest Price from (+)-Biotin-PEG4-Hydrazide manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Biotin-PEG4-hydrazide 756525-97-0
Price: US $0.00/mg
Min. Order: 100mg
Purity: >95.00%
Supply Ability: 100mg
Release date: 2024-03-30

756525-97-0, (+)-Biotin-PEG4-HydrazideRelated Search:

MPEG3-NHS 1-AMinooctaethylene Glycol FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID Bis-PE21- NHS ester 1-AMINO-3,6,9-TRIOXAUNDECANYL-11-OL Bis(NHS)PEG5 m-PEG8-NHS ester Biotin-PEG5-hydrazide Biotin-PEG5-Amine Biotin-PEG5-Mal Acetylene-PEG4-biotin conjugate Biotin-PEG5-CH2CH2COOH Biotin-PEG4-SH Biotin-PEG5-SH Biotin-PEG5-azide Biotin-PEG5-oxyamine HCl salt Biotin-PEG5-TFP Biotin-PEG4-oxyamine HCl salt

(+)-Biotin-PEG4-Hydrazide

Biotin-dPEG(R)4-hydrazide

Biotin-PEG4-Propinonic hydrazide

4,7,10,13-Tetraoxa-16-azaheneicosanoic acid, 21-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-17-oxo-, hydrazide

Biotin-dPEG??-hydrazide

15-(Biotinamido)-4,7,10,13-tetraoxapentadecanehydrazide

N-[2-[2-[2-[2-(3-Hydrazinyl-3-oxopropoxy)ethoxy]ethoxy]ethoxy]ethyl]biotinamide

4-hydrazide

Biotin-dPEG&reg

5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-[14-(hydrazinecarbonyl)-3,6,9,12-tetraoxatetradecan-1-yl]pentanamide

Biotin-dPEG<sup>?</sup><sub>4</sub>-hydrazide

Biotin-dPEG??-hydrazide (QBD-10219)

(+)-biotin-peg4-hydrazide

Biotin-PEG4-hydrazide

756525-97-0

C21H39N5O7S