Biotin-PEG4-SH
- Product Name
- Biotin-PEG4-SH
- CAS No.
- 2762393-22-4
- Chemical Name
- Biotin-PEG4-SH
- Synonyms
- Biotin-PEG4-SH;N-(14-Mercapto-3,6,9,12-tetraoxatetradecyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide;1H-Thieno[3,4-d]imidazole-4-pentanamide, hexahydro-N-(14-mercapto-3,6,9,12-tetraoxatetradec-1-yl)-2-oxo-, (3aS,4S,6aR)-;5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-(14-sulfanyl-3,6,9,12-tetraoxatetradecan-1-yl)pentanamide
- CBNumber
- CB43166097
- Molecular Formula
- C20H37N3O6S2
- Formula Weight
- 479.66
- MOL File
- 2762393-22-4.mol
Biotin-PEG4-SH Property
- Boiling point:
- 736.2±60.0 °C(predicted)
- Density
- 1.173±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
- pka
- 9.64±0.10(predicted)
- form
- Oil
- color
- Off-white to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330Rinse mouth.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
Biotin-PEG4-SH Chemical Properties,Usage,Production
Uses
Biotin-PEG4-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Biotin-PEG4-SH Preparation Products And Raw materials
Raw materials
Preparation Products
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