ChemicalBook > CAS DataBase List > (+)-Biotin-PEG4-Hydrazide

(+)-Biotin-PEG4-Hydrazide

Product Name
(+)-Biotin-PEG4-Hydrazide
CAS No.
756525-97-0
Chemical Name
(+)-Biotin-PEG4-Hydrazide
Synonyms
4-hydrazide;Biotin-dPEG®Biotin-PEG4-hydrazide;Biotin-dPEG??-hydrazide;Biotin-dPEG(R)4-hydrazide;(+)-Biotin-PEG4-Hydrazide;(+)-biotin-peg4-hydrazide;Biotin-PEG4-Propinonic hydrazide;Biotin-dPEG??-hydrazide (QBD-10219);Biotin-dPEG?4-hydrazide
CBNumber
CB73155023
Molecular Formula
C21H39N5O7S
Formula Weight
505.63
MOL File
756525-97-0.mol
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(+)-Biotin-PEG4-Hydrazide Property

Boiling point:
825.5±65.0 °C(Predicted)
Density 
1.201±0.06 g/cm3(Predicted)
storage temp. 
-20°C
form 
solid or viscous liquid
pka
12.82±0.35(Predicted)
color 
White to Light yellow
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Safety

HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
QBD10219
Product name
Biotin-dPEG®4-hydrazide
Packaging
50MG
Price
$633
Updated
2025/07/31
Sigma-Aldrich
Product number
QBD10219
Product name
Biotin-dPEG®4-hydrazide
Packaging
1000MG
Price
$1600
Updated
2025/07/31
TCI Chemical
Product number
B5578
Product name
Biotin-PEG4-Hydrazide
Purity
>94.0%(HPLC)
Packaging
10mg
Price
$80
Updated
2025/07/31
TCI Chemical
Product number
B5578
Product name
Biotin-PEG4-Hydrazide
Purity
>94.0%(HPLC)
Packaging
50mg
Price
$235
Updated
2025/07/31
dPEG
Product number
10219
Product name
Biotin-dPEG®₄-hydrazide
Packaging
50mg
Price
$170
Updated
2021/12/16
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(+)-Biotin-PEG4-Hydrazide Chemical Properties,Usage,Production

Description

Biotin-PEG4-hydrazide is a biotinylation reagent that can be used to label glycoproteins, carbohydrate-containing compounds that have oxidizable sugars or aldehydes. Hydrazine moiety reacts with an aldehyde to form semi-permanent hydrazone bonds. The hydrophilic PEG arm imparts water solubility that is transferred to the biotinylated molecule.

Uses

Biotin-PEG4-hydrazide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

reaction suitability

reagent type: cross-linking reagent
reaction type: Biotinylations
reactivity: carbonyl reactive

IC 50

PEGs

References

[1] Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521. DOI:10.1038/nchembio.2329

(+)-Biotin-PEG4-Hydrazide Preparation Products And Raw materials

Raw materials

Preparation Products

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(+)-Biotin-PEG4-Hydrazide Suppliers

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View Lastest Price from (+)-Biotin-PEG4-Hydrazide manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Biotin-PEG4-hydrazide 756525-97-0
Price
US $0.00/mg
Min. Order
100mg
Purity
>95.00%
Supply Ability
100mg
Release date
2024-03-30

756525-97-0, (+)-Biotin-PEG4-HydrazideRelated Search:

MPEG3-NHS 1-AMinooctaethylene Glycol FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID Bis-PE21- NHS ester 1-AMINO-3,6,9-TRIOXAUNDECANYL-11-OL Bis(NHS)PEG5 m-PEG8-NHS ester Biotin-PEG5-hydrazide Biotin-PEG5-Amine Biotin-PEG5-Mal Acetylene-PEG4-biotin conjugate Biotin-PEG5-CH2CH2COOH Biotin-PEG4-SH Biotin-PEG5-SH Biotin-PEG5-azide Biotin-PEG5-oxyamine HCl salt Biotin-PEG5-TFP Biotin-PEG4-oxyamine HCl salt

  • (+)-Biotin-PEG4-Hydrazide
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  • 4,7,10,13-Tetraoxa-16-azaheneicosanoic acid, 21-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-17-oxo-, hydrazide
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  • Biotin-dPEG??-hydrazide (QBD-10219)
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  • 756525-97-0
  • C21H39N5O7S