ChemicalBook > CAS DataBase List > FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID

FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID

Product Name
FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID
CAS No.
557756-85-1
Chemical Name
FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID
Synonyms
FMoc-NH-PEG4-CH2CH2COOH;1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid;Fmoc-NH-PEG4-COOH;Fmoc-NH-(PEG)3-COOH;Fmoc-PEG4-propionic acid;3-[2-[2-[2-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propionic acid;Fmoc-PEG4-OH;FMOC-15-AMINO-4;FmocNH-PEG5-acid;Fmoc-NH-PEG4c-COOH
CBNumber
CB5201606
Molecular Formula
C26H33NO8
Formula Weight
487.54
MOL File
557756-85-1.mol
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FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID Property

Boiling point:
682.1±55.0 °C(Predicted)
Density 
1.219
storage temp. 
-20°C
solubility 
Soluble in DMSO, DCM, DMF
form 
solid or viscous liquid
pka
4.28±0.10(Predicted)
color 
Colorless to light yellow
InChI
InChI=1S/C26H33NO8/c28-25(29)9-11-31-13-15-33-17-18-34-16-14-32-12-10-27-26(30)35-19-24-22-7-3-1-5-20(22)21-6-2-4-8-23(21)24/h1-8,24H,9-19H2,(H,27,30)(H,28,29)
InChIKey
NUHRPLKTAAVHCZ-UHFFFAOYSA-N
SMILES
C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)(=O)NCCOCCOCCOCCOCCC(O)=O
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Safety

Safety Statements 
24/25
HS Code 
29225090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.51035
Product name
Fmoc-NH-(PEG)₃-COOH (16 atoms)
Purity
Novabiochem<SUP>&#174;</SUP>
Packaging
1 g
Price
$587
Updated
2025/07/31
ChemScene
Product number
CS-W000434
Product name
Fmoc-NH-PEG4-CH2CH2COOH
Purity
98.75%
Packaging
250mg
Price
$53
Updated
2021/12/16
Activate Scientific
Product number
AS115286
Product name
FmocNH-PEG4-CH2CH2COOH
Purity
98+%
Packaging
250mg
Price
$98
Updated
2021/12/16
dPEG
Product number
10213
Product name
Fmoc-N-amido-dPEG??-acid
Packaging
100mg
Price
$100
Updated
2021/12/16
BroadPharm
Product number
BP-20989
Product name
Fmoc-N-amido-PEG4-acid
Purity
98%
Packaging
500mg
Price
$120
Updated
2021/12/16
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FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID Chemical Properties,Usage,Production

Description

Fmoc-N-amido-PEG4-acid is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Chemical Properties

Yellow oil

Uses

Fmoc-NH-PEG4-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG4-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

reaction suitability

reaction type: Pegylations
reagent type: cross-linking reagent

IC 50

Cleavable Linker; PEGs

References

[1] Cai P, et al. Synthesis of C3-Alkylated Indoles on DNA via Indolyl Alcohol Formation Followed by Metal-FreeTransfer Hydrogenation. Org Lett. 2019 Aug 14. DOI:10.1021/acs.orglett.9b02132

FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID Suppliers

China 165 France 1 India 2 United Kingdom 1 United States 19 Global 188
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID manufacturers

LAURENT
Product
Fmoc-NH-PEG4-CH2CH2COOH 557756-85-1
Price
US $36.58/g
Min. Order
10g
Purity
98%
Supply Ability
300kg
Release date
2025-11-17
XIAMEN SINOPEG BIOTECH CO., LTD.
Product
1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid 557756-85-1
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1g/bottle, 10g/bottle, 100g/bottle
Release date
2025-09-12
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
Fmoc-NH-PEG4-CH2CH2COOH 557756-85-1
Price
US $2.00-6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-08-06

557756-85-1, FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACIDRelated Search:

Bis-PE21- NHS ester 1-AMINO-3,6,9-TRIOXAUNDECANYL-11-OL Bis(NHS)PEG5 m-PEG8-NHS ester alpha-MaleiMidopropionyl-oMega-succiniMidyl-8(ethylene glycol) FMOC-18-AMINO-4,7,10,13,16-PENTAOXAOCTADECANOIC ACID 2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL FMoc-NH-PEG9-CH2CH2COOH 5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid,1-(9-fluren-9-ylmethyl)ester 3,6,9,12,15,18-Hexaoxanonadecane-1-thiol 5,8,11-Trioxa-2-azatridecanoic,13-amino,1,1-dimethylethyl ester FmocNH-PEG4-t-butyl acetate FmocNH-PEG5-t-butly ester 5,8,11,14-Tetraoxa-2-azahexadecanedioic acid MPEG3-NHS 1-AMinooctaethylene Glycol (+)-Biotin-PEG4-Hydrazide FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID

  • FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID
  • FMoc-15-aMino-4,7,10,13-tetraoxapentadecacanoic acid
  • FMoc-NH-PEG4-CH2CH2COOH
  • 3-[2-[2-[2-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propionic acid
  • 5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid 1-(9H-fluoren-9-ylmethyl) ester
  • 3-[2-[2-[2-[2-(9H-fluoren-9-ylMethoxycarbonylaMino)ethoxy]ethoxy]ethoxy]ethoxy]propanoicacid
  • 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid
  • FmocNH-PEG5-acid
  • Fmoc-N-amido-PEG4-acid
  • Fmoc-PEG4- CH2CH2COOH
  • Fmoc-PEG4-propionic acid
  • Fmoc-15-amino-4,7,10,13-tetraoxapentadecanoic acid≥ 97% (HPLC)
  • Fmoc-NH-(PEG)3-COOH
  • 1-(9H-Fluoren-9-yl)-3-oxo-2,7,1,13,16-pentaoxa-4-azanonadecan-19-oic acid
  • Fmoc-NH-PEG4-COOH
  • Fmoc-PEG4-OH 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid
  • Fmoc-N-amido-dPEG(R)4-acid
  • 15-(Fmoc-amino)-4,7,10,13-tetraoxapentadecanoic Acid
  • 1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3,6,9,12-tetraoxapentadecan-15-oic acid
  • Fmoc-NH-PEG4c-COOH
  • FMOC-AMINO-PEG4-PROPANOIC ACID
  • Moc-NH-PEG3-CH2CH2COOH
  • 13-TETRAOXAPENTADECANOIC ACID
  • FMOC-15-AMINO-4
  • Fmoc-NH-PEG4-CH2CH2COOH/5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester
  • FmocNH-PEG4-C2-COOH
  • Fmoc-N-amido-PEG4-propionic acid
  • Fmoc-PEG4-OH
  • Fmoc-NH-(PEG)4-CH2CH2COOH - 1 g
  • Fmoc-NH-(PEG)?-COOH (16 atoms)
  • Fmoc-N-amido-dPEG<sup>?</sup><sub>4</sub>-acid
  • Fmoc-N-amido-dPEG??-acid (QBD-10213)
  • Fmoc-NH-dPEG?4-propionic acid
  • Fmoc-NH-PEG4-Propionic Acid
  • 557756-85-1
  • C26H33NO8
  • peg