ChemicalBook > CAS DataBase List > FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID

FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID

Product Name: FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID
CAS No.: 557756-85-1
Chemical Name: FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID
Synonyms: FMoc-NH-PEG4-CH2CH2COOH;1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid;Fmoc-NH-PEG4-COOH;Fmoc-NH-(PEG)3-COOH;Fmoc-PEG4-propionic acid;3-[2-[2-[2-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propionic acid;Fmoc-PEG4-OH;FMOC-15-AMINO-4;FmocNH-PEG5-acid;Fmoc-NH-PEG4c-COOH
CBNumber: CB5201606
Molecular Formula: C26H33NO8
Formula Weight: 487.54
MOL File: 557756-85-1.mol

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FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID Property

Boiling point:: 682.1±55.0 °C(Predicted)
Density: 1.219
storage temp.: -20°C
solubility: Soluble in DMSO, DCM, DMF
form: solid or viscous liquid
pka: 4.28±0.10(Predicted)
color: Colorless to light yellow
InChI: InChI=1S/C26H33NO8/c28-25(29)9-11-31-13-15-33-17-18-34-16-14-32-12-10-27-26(30)35-19-24-22-7-3-1-5-20(22)21-6-2-4-8-23(21)24/h1-8,24H,9-19H2,(H,27,30)(H,28,29)
InChIKey: NUHRPLKTAAVHCZ-UHFFFAOYSA-N
SMILES: C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)(=O)NCCOCCOCCOCCOCCC(O)=O

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Safety

Safety Statements: 24/25
HS Code: 29225090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.51035
Product name: Fmoc-NH-(PEG)₃-COOH (16 atoms)
Purity: Novabiochem®
Packaging: 1 g
Price: $587
Updated: 2025/07/31

Activate Scientific

Product number: AS115286
Product name: FmocNH-PEG4-CH2CH2COOH
Purity: 98+%
Packaging: 5G
Price: $658
Updated: 2021/12/16

ChemScene

Product number: CS-W000434
Product name: Fmoc-NH-PEG4-CH2CH2COOH
Purity: 98.75%
Packaging: 10g
Price: $675
Updated: 2021/12/16

Iris Biotech GmbH

Product number: PEG1820
Product name: Fmoc-NH-PEG(4)-COOH
Packaging: 5G
Price: $675
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: JK992268
Product name: Fmoc-15-amino-4,7,10,13-tetraoxapentadecanoicacid
Packaging: 250mg
Price: $701
Updated: 2021/12/16

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FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID Chemical Properties,Usage,Production

Description

Fmoc-N-amido-PEG4-acid is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Chemical Properties

Yellow oil

Uses

Fmoc-NH-PEG4-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG4-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

reaction suitability

reaction type: Pegylations
reagent type: cross-linking reagent

IC 50

Cleavable Linker; PEGs

References

[1] Cai P, et al. Synthesis of C3-Alkylated Indoles on DNA via Indolyl Alcohol Formation Followed by Metal-FreeTransfer Hydrogenation. Org Lett. 2019 Aug 14. DOI:10.1021/acs.orglett.9b02132

FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID Suppliers

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View Lastest Price from FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID manufacturers

LAURENT

Product: Fmoc-NH-PEG4-CH2CH2COOH 557756-85-1
Price: US $36.58/g
Min. Order: 10g
Purity: 98%
Supply Ability: 300kg
Release date: 2025-11-17

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid 557756-85-1
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
Release date: 2025-09-12

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: Fmoc-NH-PEG4-CH2CH2COOH 557756-85-1
Price: US $2.00-6.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-08-06

557756-85-1, FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACIDRelated Search:

Bis-PE21- NHS ester 1-AMINO-3,6,9-TRIOXAUNDECANYL-11-OL Bis(NHS)PEG5 m-PEG8-NHS ester alpha-MaleiMidopropionyl-oMega-succiniMidyl-8(ethylene glycol) FMOC-18-AMINO-4,7,10,13,16-PENTAOXAOCTADECANOIC ACID 2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL FMoc-NH-PEG9-CH2CH2COOH 5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid,1-(9-fluren-9-ylmethyl)ester 3,6,9,12,15,18-Hexaoxanonadecane-1-thiol 5,8,11-Trioxa-2-azatridecanoic,13-amino,1,1-dimethylethyl ester FmocNH-PEG4-t-butyl acetate FmocNH-PEG5-t-butly ester 5,8,11,14-Tetraoxa-2-azahexadecanedioic acid MPEG3-NHS 1-AMinooctaethylene Glycol (+)-Biotin-PEG4-Hydrazide FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID

FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID

FMoc-15-aMino-4,7,10,13-tetraoxapentadecacanoic acid

FMoc-NH-PEG4-CH2CH2COOH

3-[2-[2-[2-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propionic acid

5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid 1-(9H-fluoren-9-ylmethyl) ester

3-[2-[2-[2-[2-(9H-fluoren-9-ylMethoxycarbonylaMino)ethoxy]ethoxy]ethoxy]ethoxy]propanoicacid

1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid

FmocNH-PEG5-acid

Fmoc-N-amido-PEG4-acid

Fmoc-PEG4- CH2CH2COOH

Fmoc-PEG4-propionic acid

Fmoc-15-amino-4,7,10,13-tetraoxapentadecanoic acid≥ 97% (HPLC)

Fmoc-NH-(PEG)3-COOH

1-(9H-Fluoren-9-yl)-3-oxo-2,7,1,13,16-pentaoxa-4-azanonadecan-19-oic acid

Fmoc-NH-PEG4-COOH

Fmoc-PEG4-OH 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid

Fmoc-N-amido-dPEG(R)4-acid

15-(Fmoc-amino)-4,7,10,13-tetraoxapentadecanoic Acid

1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3,6,9,12-tetraoxapentadecan-15-oic acid

Fmoc-NH-PEG4c-COOH

FMOC-AMINO-PEG4-PROPANOIC ACID

Moc-NH-PEG3-CH2CH2COOH

13-TETRAOXAPENTADECANOIC ACID

FMOC-15-AMINO-4

Fmoc-NH-PEG4-CH2CH2COOH/5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester

FmocNH-PEG4-C2-COOH

Fmoc-N-amido-PEG4-propionic acid

Fmoc-PEG4-OH

Fmoc-NH-(PEG)4-CH2CH2COOH - 1 g

Fmoc-NH-(PEG)?-COOH (16 atoms)

Fmoc-N-amido-dPEG?4-acid

Fmoc-N-amido-dPEG??-acid (QBD-10213)

Fmoc-NH-dPEG?4-propionic acid

Fmoc-NH-PEG4-Propionic Acid

557756-85-1

C26H33NO8

peg