2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL
- Product Name
- 2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL
- CAS No.
- 6338-55-2
- Chemical Name
- 2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL
- Synonyms
- 2-(2-(2-aminoethoxy)ethoxy)ethan-1-ol;NH2-PEG3-OH;Amino-PEG3;H2N-PEG3-OH;HO-PEG3-NH2;Amino-PEG3-alcohol;MA 10;T3EGMA;NSC40760;Triglycolamine
- CBNumber
- CB0386760
- Molecular Formula
- C6H15NO3
- Formula Weight
- 149.19
- MOL File
- 6338-55-2.mol
2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL Property
- Boiling point:
- 120-130℃ (4 Torr)
- Density
- 1.0773 g/cm3at 20℃(lit.)
- refractive index
- 1.4645 (589.3 nm 20℃)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- solubility
- DMF: 30 mg/ml; DMSO: 10 mg/ml; Ethanol: 15 mg/ml; PBS (pH 7.2): 10 mg/ml
- form
- clear liquid
- pka
- 14.36±0.10(Predicted)
- color
- Colorless to Light yellow to Light orange
- Appearance
- colorless liquid
- BRN
- 1739188
- InChI
- InChI=1S/C6H15NO3/c7-1-3-9-5-6-10-4-2-8/h8H,1-7H2
- InChIKey
- ASDQMECUMYIVBG-UHFFFAOYSA-N
- SMILES
- C(O)COCCOCCN
- CAS DataBase Reference
- 6338-55-2
- EPA Substance Registry System
- Ethanol, 2-[2-(2-aminoethoxy)ethoxy]- (6338-55-2)
Safety
- Hazard Codes
- C,Xi
- Risk Statements
- 41-34-37/38
- Safety Statements
- 26-39-45-36/37/39
- RIDADR
- 2735
- WGK Germany
- 3
- HazardClass
- 8
- PackingGroup
- Ⅱ
- HS Code
- 2922500090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- 768901
- Product name
- 2-[2-(2-Aminoethoxy)ethoxy]ethanol
- Purity
- ≥96.0% (GC)
- Packaging
- 250mg
- Price
- $56.28
- Updated
- 2025/07/31
- Product number
- 768901
- Product name
- 2-[2-(2-Aminoethoxy)ethoxy]ethanol
- Purity
- ≥96.0% (GC)
- Packaging
- 1g
- Price
- $144
- Updated
- 2025/07/31
- Product number
- A2420
- Product name
- Amino-PEG3
- Packaging
- 1G
- Price
- $161
- Updated
- 2025/07/31
- Product number
- 30426
- Product name
- (PEO)3-monoamine
- Packaging
- 100mg
- Price
- $61
- Updated
- 2024/03/01
- Product number
- 30426
- Product name
- (PEO)3-monoamine
- Packaging
- 250mg
- Price
- $116
- Updated
- 2024/03/01
2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL Chemical Properties,Usage,Production
Description
(PEO)3-monoamine is a poly(ethylene oxide) (PEO) blocking reagent that prevents nonspecific adsorption of analytes in applications using covalent protein coupling such as ELISA. It reduces the adsorption of IgG when coated on carboxylic-terminated surfaces.
Uses
(PEO)3-Mono-amine can be used as a novel improved cutting fluid.
Synthesis
86520-52-7
6338-55-2
The general procedure for the synthesis of 2-[2-(2-aminoethoxy)ethoxy]ethanol from 2-(2-(2-azidoethoxy)ethoxy)ethanol was as follows: 2-(2-(2-azidoethoxy)ethoxy)ethanol (0.7 g, 3.99 mmol) was dissolved in methanol (9 mL), followed by addition of a palladium/activated carbon catalyst (0.196 g) under stirring conditions . The reaction flask was subjected to three evacuation/hydrogen flush cycles to establish a hydrogen atmosphere. The progress of the reaction was monitored by thin layer chromatography (TLC), which showed the completion of the reaction after 8 hours. The reaction mixture was filtered through diatomaceous earth to remove the palladium/activated carbon catalyst. The filtrate was concentrated under reduced pressure to afford 2-[2-(2-aminoethoxy)ethoxy]ethanol as a colorless oil (0.6 g, quantitative yield).
IC 50
PEGs
References
[1] Helvetica Chimica Acta, 1991, vol. 74, # 8, p. 1697 - 1706
[2] Patent: US5144043, 1992, A
[3] Organic Letters, 2009, vol. 11, # 1, p. 193 - 196
[4] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 2, p. 1151 - 1155
[5] Angewandte Chemie - International Edition, 2015, vol. 54, # 35, p. 10327 - 10330
2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL manufacturers
- Product
- NH2-PEG3-OH 6338-55-2
- Price
- US $10.52/g
- Min. Order
- 10g
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2025-11-22
- Product
- 2-(2-(2-aminoethoxy)ethoxy)ethanol 6338-55-2
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2025-09-11
- Product
- 2-[2-(2-Aminoethoxy)ethoxy]ethanol 6338-55-2
- Price
- US $2.00-6.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-08-05