MC-Val-Cit-PAB

Product Name: MC-Val-Cit-PAB
CAS No.: 159857-80-4
Chemical Name: MC-Val-Cit-PAB
Synonyms: N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide;6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)hexanamide;MC-Val-Cit-PAB-OH;EOS-60616;MC-Val-it-PAB;MC-Val-Cit-PAB;ML-Val-Cit-PAB;MC-Val-Cit-PAB/MC-VC-PAB-OH;Benzenemethanol,2-chloro-8-nitro-;MC-Val-Cit-PAB (ADC peptide linker)
CBNumber: CB02554361
Molecular Formula: C28H40N6O7
Formula Weight: 572.65
MOL File: 159857-80-4.mol

More

Less

MC-Val-Cit-PAB Property

Boiling point:: 931.6±65.0 °C(Predicted)
Density: 1.276
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: DMSO: soluble
form: powder to crystal
pka: 13.41±0.70(Predicted)
color: White to Almost white
InChIKey: UMDCMQHPXQLHGR-OFVILXPXSA-N
SMILES: C(N)(=O)[C@H](CCCNC(N)=O)N(C(=O)[C@H](C(C)C)NC(=O)CCCCCN1C(=O)C=CC1=O)C1=CC=C(CO)C=C1
CAS DataBase Reference: 159857-80-4

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: M3224
Product name: MC-Val-Cit-PAB-OH
Packaging: 100MG
Price: $281
Updated: 2024/03/01

TCI Chemical

Product number: M3224
Product name: MC-Val-Cit-PAB-OH
Packaging: 500MG
Price: $845
Updated: 2024/03/01

Cayman Chemical

Product number: 28285
Product name: Mc-Val-Cit-PAB
Packaging: 5mg
Price: $100
Updated: 2024/03/01

Cayman Chemical

Product number: 28285
Product name: Mc-Val-Cit-PAB
Packaging: 50mg
Price: $739
Updated: 2024/03/01

Cayman Chemical

Product number: 28285
Product name: Mc-Val-Cit-PAB
Packaging: 1mg
Price: $34
Updated: 2024/03/01

More

Less

MC-Val-Cit-PAB Chemical Properties,Usage,Production

Description

MC-Val-Cit-PAB-OH is a cleavable peptide linker. The Val-Cit was designed to be cleaved specifically by Cathepsin B. MC group is reactive with thiol moiety

Uses

N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide is used as a reagent to prepare antibody-drug conjugates, which are compounds that selectively deliver cytotoxic drugs to a tumour-associated antigen.

MC-Val-Cit-PAB Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

MC-Val-Cit-PAB Suppliers

Americas 1 China 161 Europe 1 India 1 Japan 1 United States 11 Global 176

Jinan Chengquan Chemical Co., Ltd

Tel: 13616405505 13616405505
Email: zhulinsun1@126.com
Country: China
ProdList: 76
Advantage: 58

Shenzhen Yuzhong Pharmaceutical Technology Co., Ltd.

Tel: 13414494621
Fax: qq: 30307604
Email: chenchao02lzu@126.com
Country: China
ProdList: 112
Advantage: 58

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: 021-58955996
Email: info@chemexpress.com
Country: China
ProdList: 691
Advantage: 58

Suzhou Sino Rare Chemical Co., Ltd.

Tel: 512-62857507
Email: sales@sinorarechem.com
Country: China
ProdList: 371
Advantage: 58

Shanghai Send Pharmaceutical Technology Co., Ltd.

Tel: +86-021-50266790 Q2816483246
Fax: 021-50266790
Email: sale@shsendpharm.com
Country: China
ProdList: 258
Advantage: 50

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: zhangsn@titansci.com
Country: China
ProdList: 14113
Advantage: 59

Daicel Chiral Technologies (China)CO.,LTD

Tel: 021-50460086-9 15921403865
Fax: +86-21-50462321
Email: han_yajun@dctc.daicel.com
Country: China
ProdList: 6854
Advantage: 65

Chengdu Pukang Biotechnology Co., Ltd

Tel: 028-82550498 19102685862
Fax: 086-28-82550468
Email: sales@pu-kang.com
Country: China
ProdList: 485
Advantage: 58

T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
Email: contact@trustwe.com
Country: China
ProdList: 9900
Advantage: 58

More

Less

View Lastest Price from MC-Val-Cit-PAB manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: MC-Val-Cit-PAB-OH 159857-80-4
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-29

Career Henan Chemical Co

Product: N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide 159857-80-4
Price: US $6.68/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg-1000kg
Release date: 2020-01-08

159857-80-4, MC-Val-Cit-PABRelated Search:

FMoc-Val-Cit-PAB-PNP Val-cit-PAB-OH pyrene-2,7-diyldiboronic acid Fmoc-Val-Cit-OH FMoc-Val-Cit-PAB

MC-Val-it-PAB

N-[(2S)-1-[[(2S)-5-(carbamoylamino)-1-[4-(hydroxymethyl)anilino]-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-6-(2,5-dioxopyrrol-1-yl)hexanamide

N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide

L-OrnithinaMide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aMinocarbonyl)-N-[4-(hydroxyMethyl)phenyl]-

6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)hexanamide

ML-Val-Cit-PAB

MC-Val-Cit-PAB, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-

MC-Val-Cit-PAB

EOS-60616

MC-Val-Cit-PAB-OH

N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymeth

6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-[(S)-1-[[(S)-1-[[4-(hydroxymethyl)phenyl]amino]-1-oxo-5-ureidopentan-2-yl]amino]-3-methyl-1-ox

N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]-L-valyl-N5-carbamoyl-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide

6-(2,5-Dioxo-2,5-dihydro-1-pyrrolyl)-N-[(S)-1-[[(S)-1-[[4-(hydroxymethyl)phenyl]amino]-1-oxo-5-ureido-2-pentyl]amino]-3-methyl-1-oxo-2-butyl]hexanamide

N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]-L-valyl-N<sup>5</sup>-carbamoyl-N<sup>2</sup>-[4-(hydroxymethyl)phenyl]-L-ornithinamide

Benzenemethanol,2-chloro-8-nitro-

MC-Val-Cit-PAB (ADC peptide linker)

6-(2,5-dioxopyrrol-1-yl)-N-[(1S)-1-[[(1S)-1-[[4-(hydroxymethyl)phenyl]carbamoyl]-4-ureido-butyl]carbamoyl]-2-methyl-propyl]hexanamide

MC-Val-Cit-PAB/MC-VC-PAB-OH

159857-80-4

59857-80-4

C28H40N6O7

ADCs

ADC Linker

ADC-Linker

ADC-Linkers