FMoc-Val-Cit-PAB

ChemicalBook > CAS DataBase List > FMoc-Val-Cit-PAB

Uses

Product Name: FMoc-Val-Cit-PAB
CAS No.: 159858-22-7
Chemical Name: FMoc-Val-Cit-PAB
Synonyms: Fmoc-Val-Cit-PAB-OH;(9H-fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate;FMoc-Val-Cit-PAB;Fomc-Val-Cit-PAB;TrastuzumabImpurity2;Fmoc-L-Val-Cit-PAB-OH;Fmoc-val-citrulline-para-aminobenzyl-OH;Trastuzumab Impurity 2 (Fmoc-Val-Cit-PAB-OH);4-(N-((9H-fluoren-9-yl)methoxycarbonyl)-L-valinyl-D-citrullinamido)benzyl alcohol;N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide
CBNumber: CB02730901
Molecular Formula: C33H39N5O6
Formula Weight: 601.69
MOL File: 159858-22-7.mol

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FMoc-Val-Cit-PAB Property

Melting point:: 204 °C(dec.)
Boiling point:: 914.2±65.0 °C(Predicted)
Density: 1.276±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Store in freezer, under -20°C
form: powder to crystal
pka: 10.63±0.46(Predicted)
color: White to Almost white
CAS DataBase Reference: 159858-22-7

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Safety

HS Code: 2924.29.7790

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TCI Chemical

Product number: F1223
Product name: Fmoc-Val-Cit-PAB-OH
Packaging: 25MG
Price: $16
Updated: 2024/03/01

TCI Chemical

Product number: F1223
Product name: Fmoc-Val-Cit-PAB-OH
Packaging: 100MG
Price: $39
Updated: 2024/03/01

AK Scientific

Product number: 2998DP
Product name: Fmoc-Val-Cit-PAB
Packaging: 25mg
Price: $259
Updated: 2021/12/16

ChemScene

Product number: CS-5170
Product name: Fmoc-Val-Cit-PAB
Purity: 97.15%
Packaging: 250mg
Price: $300
Updated: 2021/12/16

Iris Biotech GmbH

Product number: ADC1030
Product name: Fmoc-Val-Cit-PAB
Packaging: 250mg
Price: $303.75
Updated: 2021/12/16

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FMoc-Val-Cit-PAB Chemical Properties,Usage,Production

Uses

Fmoc-Val-Cit-PAB is a commonly used bridge for a degradable antibody-conjugated drug (ADC).

Description

Fmoc-Val-Cit-PAB-OH is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. Fmoc can be deprotected under basic condition.

FMoc-Val-Cit-PAB Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from FMoc-Val-Cit-PAB manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: FMoc-Val-Cit-PAB 159858-22-7
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-05-24

Xian confluore Biological Technology Co., Ltd.

Product: Fmoc-Val-Cit-PAB-OH 159858-22-7
Price: US $0.00/g
Min. Order: 10g
Purity: >95.00%
Supply Ability: 10g
Release date: 2024-03-29

Henan Aochuang Chemical Co.,Ltd.

Product: FMoc-Val-Cit-PAB 159858-22-7
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-13

159858-22-7, FMoc-Val-Cit-PABRelated Search:

FMoc-Val-Cit-PAB-PNP Val-cit-PAB-OH pyrene-2,7-diyldiboronic acid Fmoc-Val-Cit-OH MC-Val-Cit-PAB

FMoc-Val-Cit-PAB

Fmoc-Val-Cit-PAB-OH

(9H-fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate

L-Ornithinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-

(9H-fluoren-9-yl)methyl((S)-1-((())-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate

(9H-fluoren-9-yl)methyl N-[(1S)-1-{[(1S)-4-(carbamoylamino)-1-{[4-(hydroxymethyl)phenyl]carbamoyl}butyl]carbamoyl}-2-methylpropyl]carbamate

Fmoc-val-citrulline-para-aminobenzyl-OH

(9H-fluoren-9-yl)methyl ((2S)-1-((1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate

4-(N-((9H-fluoren-9-yl)methoxycarbonyl)-L-valinyl-D-citrullinamido)benzyl alcohol

TrastuzumabImpurity2

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide

9H-fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbam

9H-fluoren-9-ylmethyl N-[(2S)-1-[[(2S)-5-(carbamoylamino)-1-[4-(hydroxymethyl)anilino]-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate

Trastuzumab Impurity 2 (Fmoc-Val-Cit-PAB-OH)

Fmoc-L-Val-Cit-PAB-OH

Fomc-Val-Cit-PAB

159858-22-7

159858-22-8

1959858-22-7

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