Fmoc-Val-Ala-PAB-OH

Product Name: Fmoc-Val-Ala-PAB-OH
CAS No.: 1394238-91-5
Chemical Name: Fmoc-Val-Ala-PAB-OH
Synonyms: Fmoc-Val-ala-PAB;(9H-Fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate;CS-2746;Fmoc-Val-Cit-PABA;Fmoc-Val-Ala-PAB-OH;1-Butanesulfonicacid,6-hydroxy-;9-fluorenylmethyloxycarbonyl-valyl-alanyl-4-aminobenzylalcohol;Fmoc-Val-Ala-PAB-OH, 9-fluorenylmethyloxycarbonyl-valyl-alanyl-4-aminobenzylalcohol;N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl-N-[4-(hydroxymethyl)phenyl]-L-alaninamide;N - [(9H-fluoren- 9 -ylmethoxy) -carbonyl] - L-valyl- N- [4 - (hy-droxymethyl)phenyl] -
CBNumber: CB53364144
Molecular Formula: C30H33N3O5
Formula Weight: 515.6
MOL File: 1394238-91-5.mol

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Fmoc-Val-Ala-PAB-OH Property

Melting point:: 218 °C(dec.)
Boiling point:: 811.1±65.0 °C(Predicted)
Density: 1.251±0.06 g/cm3(Predicted)
solubility: DMSO : 33.33 mg/mL (64.64 mM; ultrasonic and warming and heat to 80°C)
pka: 10.63±0.46(Predicted)
form: powder to crystal
color: White to Light yellow

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Safety

HS Code: 2924.29.7790

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: F1278
Product name: Fmoc-Val-Ala-PAB-OH
Packaging: 250MG
Price: $257
Updated: 2024/03/01

TRC

Product number: F861090
Product name: Fmoc-Val-Ala-PAB
Packaging: 100mg
Price: $155
Updated: 2021/12/16

TRC

Product number: F861090
Product name: Fmoc-Val-Ala-PAB
Packaging: 250mg
Price: $305
Updated: 2021/12/16

Iris Biotech GmbH

Product number: ADC1060
Product name: Fmoc-Val-Ala-PAB
Packaging: 250mg
Price: $303.75
Updated: 2021/12/16

ChemScene

Product number: CS-0102865
Product name: Fmoc-Val-Ala-PAB-OH
Packaging: 100mg
Price: $508
Updated: 2021/12/16

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Fmoc-Val-Ala-PAB-OH Chemical Properties,Usage,Production

Description

Fmoc-Val-Ala-PAB is a cleavable ADC linker. The Val-Ala is effectively cleaved by lysosomal proteolytic enzymes while being highly stable in human plasma, making this a potentent stragy in ADC linker design. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations.

Uses

Fmoc-Val-Ala-PAB is a building block used in the synthesis of RGD peptidomimetic-paclitaxel conjugates bearing lysosomally cleavable linkers.

Fmoc-Val-Ala-PAB-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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Fmoc-Val-Ala-PAB-OH Suppliers

Americas 1 China 97 Europe 1 India 2 Japan 1 United States 5 Global 107

Shenzhen Yuzhong Pharmaceutical Technology Co., Ltd.

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SuZhou JianHua Pharmaceutical Co. Ltd

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Hygeia (Chengdu) pharmaceutical technique Co., Ltd

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TOKYO CHEMICAL INDUSTRY CO., LTD.

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Email: Sales-JP@TCIchemicals.com
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TCI Europe

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Country: Europe
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DebyeTec.com Inc.

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Shanghai TBBMed Co.,Ltd

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View Lastest Price from Fmoc-Val-Ala-PAB-OH manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Fmoc-Val-Ala-PAB 1394238-91-5
Price: US $0.00/g
Min. Order: 1g
Purity: >95.00%
Supply Ability: 1g
Release date: 2024-03-29

Henan Aochuang Chemical Co.,Ltd.

Product: Fmoc-Val-Ala-PAB-OH 1394238-91-5
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-13

1394238-91-5, Fmoc-Val-Ala-PAB-OHRelated Search:

Fmoc-Val-Ala-OH Fmoc-Val-Ala-OSu Calcium hydroxide FMoc-Val-Cit-PAB Fmoc-Val-Cit-OH N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycylglycylglycylglycine H-GLY-GLY-PHE-OH Fomc-Gly-Gly-Phe-Gly-OH

CS-2746

Fmoc-Val-ala-PAB

Fmoc-Val-Ala-PAB-OH, 9-fluorenylmethyloxycarbonyl-valyl-alanyl-4-aminobenzylalcohol

L-Alaninamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N-[4-(hydroxymethyl)phenyl]-

Fmoc-Val-Ala-PAB-OH

(9H-Fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate

1-Butanesulfonicacid,6-hydroxy-

Inhibitor,Antibody-drug conjugates linkers,ADC Linkers,Fmoc Val Ala PAB OH,inhibit,FmocValAlaPABOH

9-fluorenylmethyloxycarbonyl-valyl-alanyl-4-aminobenzylalcohol

Fmoc-Val-Cit-PABA

(S)-2-(Fmoc-amino)-N-[(S)-1-[[4-(hydroxymethyl)phenyl]amino]-1-oxo-2-propyl]-3-methylbutanamide

(9H-fluoren-9-yl)methyl N-[(1S)-1-{[(1S)-1-[(4-(hydroxymethyl)phenyl)carbamoyl]ethyl]carbamoyl}-2-methylpropyl]carbamate

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl-N-[4-(hydroxymethyl)phenyl]-L-alaninamide

N - [(9H-fluoren- 9 -ylmethoxy) -carbonyl] - L-valyl- N- [4 - (hy-droxymethyl)phenyl] -

1394238-91-5

Linker

ADCs Linkers

ADCs

ADC LINKER

ADC-Linker