Fmoc-Val-Ala-PAB-OH
- Product Name
- Fmoc-Val-Ala-PAB-OH
- CAS No.
- 1394238-91-5
- Chemical Name
- Fmoc-Val-Ala-PAB-OH
- Synonyms
- Fmoc-Val-ala-PAB;(9H-Fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate;CS-2746;Fmoc-Val-Cit-PABA;Fmoc-Val-Ala-PAB-OH;1-Butanesulfonicacid,6-hydroxy-;9-fluorenylmethyloxycarbonyl-valyl-alanyl-4-aminobenzylalcohol;Fmoc-Val-Ala-PAB-OH, 9-fluorenylmethyloxycarbonyl-valyl-alanyl-4-aminobenzylalcohol;L-Alaninamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N-[4-(hydroxymethyl)phenyl]-;(S)-2-(Fmoc-amino)-N-[(S)-1-[[4-(hydroxymethyl)phenyl]amino]-1-oxo-2-propyl]-3-methylbutanamide
- CBNumber
- CB53364144
- Molecular Formula
- C30H33N3O5
- Formula Weight
- 515.6
- MOL File
- 1394238-91-5.mol
Fmoc-Val-Ala-PAB-OH Property
- Melting point:
- 218 °C(dec.)
- Boiling point:
- 811.1±65.0 °C(Predicted)
- Density
- 1.251±0.06 g/cm3(Predicted)
- solubility
- DMSO : 33.33 mg/mL (64.64 mM; ultrasonic and warming and heat to 80°C)
- pka
- 10.63±0.46(Predicted)
- form
- powder to crystal
- color
- White to Light yellow
Safety
- HS Code
- 2924.29.7790
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- F1278
- Product name
- Fmoc-Val-Ala-PAB-OH
- Packaging
- 250MG
- Price
- $257
- Updated
- 2024/03/01
- Product number
- F861090
- Product name
- Fmoc-Val-Ala-PAB
- Packaging
- 250mg
- Price
- $305
- Updated
- 2021/12/16
- Product number
- F861090
- Product name
- Fmoc-Val-Ala-PAB
- Packaging
- 100mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- CS-0102865
- Product name
- Fmoc-Val-Ala-PAB-OH
- Packaging
- 100mg
- Price
- $508
- Updated
- 2021/12/16
- Product number
- ADC1060
- Product name
- Fmoc-Val-Ala-PAB
- Packaging
- 1g
- Price
- $877.5
- Updated
- 2021/12/16
Fmoc-Val-Ala-PAB-OH Chemical Properties,Usage,Production
Description
Fmoc-Val-Ala-PAB is a cleavable ADC linker. The Val-Ala is effectively cleaved by lysosomal proteolytic enzymes while being highly stable in human plasma, making this a potentent stragy in ADC linker design. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations.
Uses
Fmoc-Val-Ala-PAB is a building block used in the synthesis of RGD peptidomimetic-paclitaxel conjugates bearing lysosomally cleavable linkers.
Fmoc-Val-Ala-PAB-OH Preparation Products And Raw materials
Raw materials
Preparation Products
Fmoc-Val-Ala-PAB-OH Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23680
- Advantage
- 75
View Lastest Price from Fmoc-Val-Ala-PAB-OH manufacturers
- Product
- Fmoc-Val-Ala-PAB 1394238-91-5
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >95.00%
- Supply Ability
- 1g
- Release date
- 2024-03-29
- Product
- Fmoc-Val-Ala-PAB-OH 1394238-91-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-13