ChemicalBook > CAS DataBase List > Fmoc-Val-Ala-PAB-OH

Fmoc-Val-Ala-PAB-OH

Product Name
Fmoc-Val-Ala-PAB-OH
CAS No.
1394238-91-5
Chemical Name
Fmoc-Val-Ala-PAB-OH
Synonyms
Fmoc-Val-ala-PAB;(9H-Fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate;CS-2746;Fmoc-Val-Cit-PABA;Fmoc-Val-Ala-PAB-OH;1-Butanesulfonicacid,6-hydroxy-;9-fluorenylmethyloxycarbonyl-valyl-alanyl-4-aminobenzylalcohol;Fmoc-Val-Ala-PAB-OH, 9-fluorenylmethyloxycarbonyl-valyl-alanyl-4-aminobenzylalcohol;L-Alaninamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N-[4-(hydroxymethyl)phenyl]-;(S)-2-(Fmoc-amino)-N-[(S)-1-[[4-(hydroxymethyl)phenyl]amino]-1-oxo-2-propyl]-3-methylbutanamide
CBNumber
CB53364144
Molecular Formula
C30H33N3O5
Formula Weight
515.6
MOL File
1394238-91-5.mol
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Fmoc-Val-Ala-PAB-OH Property

Melting point:
218 °C(dec.)
Boiling point:
811.1±65.0 °C(Predicted)
Density 
1.251±0.06 g/cm3(Predicted)
solubility 
DMSO : 33.33 mg/mL (64.64 mM; ultrasonic and warming and heat to 80°C)
pka
10.63±0.46(Predicted)
form 
powder to crystal
color 
White to Light yellow
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Safety

HS Code 
2924.29.7790
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
F1278
Product name
Fmoc-Val-Ala-PAB-OH
Packaging
250MG
Price
$257
Updated
2024/03/01
TRC
Product number
F861090
Product name
Fmoc-Val-Ala-PAB
Packaging
250mg
Price
$305
Updated
2021/12/16
TRC
Product number
F861090
Product name
Fmoc-Val-Ala-PAB
Packaging
100mg
Price
$155
Updated
2021/12/16
ChemScene
Product number
CS-0102865
Product name
Fmoc-Val-Ala-PAB-OH
Packaging
100mg
Price
$508
Updated
2021/12/16
Iris Biotech GmbH
Product number
ADC1060
Product name
Fmoc-Val-Ala-PAB
Packaging
1g
Price
$877.5
Updated
2021/12/16
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Fmoc-Val-Ala-PAB-OH Chemical Properties,Usage,Production

Description

Fmoc-Val-Ala-PAB is a cleavable ADC linker. The Val-Ala is effectively cleaved by lysosomal proteolytic enzymes while being highly stable in human plasma, making this a potentent stragy in ADC linker design. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations.

Uses

Fmoc-Val-Ala-PAB is a building block used in the synthesis of RGD peptidomimetic-paclitaxel conjugates bearing lysosomally cleavable linkers.

Fmoc-Val-Ala-PAB-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Fmoc-Val-Ala-PAB-OH manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Fmoc-Val-Ala-PAB 1394238-91-5
Price
US $0.00/g
Min. Order
1g
Purity
>95.00%
Supply Ability
1g
Release date
2024-03-29
Henan Aochuang Chemical Co.,Ltd.
Product
Fmoc-Val-Ala-PAB-OH 1394238-91-5
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1Ton
Release date
2022-10-13

1394238-91-5, Fmoc-Val-Ala-PAB-OHRelated Search:

Fmoc-Val-Ala-OH Fmoc-Val-Ala-OSu Calcium hydroxide

  • CS-2746
  • Fmoc-Val-ala-PAB
  • Fmoc-Val-Ala-PAB-OH, 9-fluorenylmethyloxycarbonyl-valyl-alanyl-4-aminobenzylalcohol
  • L-Alaninamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N-[4-(hydroxymethyl)phenyl]-
  • Fmoc-Val-Ala-PAB-OH
  • (9H-Fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate
  • 1-Butanesulfonicacid,6-hydroxy-
  • Inhibitor,Antibody-drug conjugates linkers,ADC Linkers,Fmoc Val Ala PAB OH,inhibit,FmocValAlaPABOH
  • 9-fluorenylmethyloxycarbonyl-valyl-alanyl-4-aminobenzylalcohol
  • Fmoc-Val-Cit-PABA
  • (S)-2-(Fmoc-amino)-N-[(S)-1-[[4-(hydroxymethyl)phenyl]amino]-1-oxo-2-propyl]-3-methylbutanamide
  • 1394238-91-5
  • Linker
  • ADCs Linkers
  • ADCs
  • ADC LINKER
  • ADC-Linker