Val-cit-PAB-OH
- Product Name
- Val-cit-PAB-OH
- CAS No.
- 159857-79-1
- Chemical Name
- Val-cit-PAB-OH
- Synonyms
- H-Val-Cit-PAB-OH;(S)-2-((S)-2-amino-3-methylbutanamido)-N-(4-(hydroxymethyl)phenyl)-5-ureidopentanamide;EOS-61316;al-Cit-PAB-OH;H-Val-Cit-PAB;Val-cit-PAB-OH;(D)-VAL-CIT-PAB;NH2-Val-Cit-PAB;2-(4-(((2,6-dimethylbenzoyl)oxy)methyl)phenyl)aceticacid;L-Valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide
- CBNumber
- CB92715206
- Molecular Formula
- C18H29N5O4
- Formula Weight
- 379.45
- MOL File
- 159857-79-1.mol
Val-cit-PAB-OH Property
- Melting point:
- 168 °C(dec.)
- Boiling point:
- 715.0±60.0 °C(Predicted)
- Density
- 1.243±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- solubility
- DMF: 10 mg/ml; DMSO: 10 mg/ml; PBS (pH 7.2): 1 mg/ml
- form
- powder to crystal
- pka
- 13.75±0.46(Predicted)
- color
- White to Almost white
Safety
- HS Code
- 2924.29.7790
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- V0155
- Product name
- Val-Cit-PAB-OH
- Packaging
- 25MG
- Price
- $160
- Updated
- 2024/03/01
- Product number
- V0155
- Product name
- Val-Cit-PAB-OH
- Packaging
- 100MG
- Price
- $482
- Updated
- 2024/03/01
- Product number
- V091545
- Product name
- Val-cit-PAB-OH
- Packaging
- 100mg
- Price
- $580
- Updated
- 2021/12/16
- Product number
- BP-23218
- Product name
- Val-Cit-PAB-OH
- Purity
- 95%
- Packaging
- 500mg
- Price
- $290
- Updated
- 2021/12/16
- Product number
- CS-5171
- Product name
- Val-cit-PAB-OH
- Purity
- 99.35%
- Packaging
- 250mg
- Price
- $157
- Updated
- 2021/12/16
Val-cit-PAB-OH Chemical Properties,Usage,Production
Description
Val-Cit-PAB-OH is a peptide cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). The Val-Cit will specifically be cleaved by Cathepsin B.
Uses
Val-cit-PAB-OH acts as a reagent in the preparation of cell-penetrating peptidic GRP78 ligand for tumor cell-specific prodrug therapy, preparation of monomethylvaline derivative conjugates with ligands and antibodies for cancer treatment.
Val-cit-PAB-OH Preparation Products And Raw materials
Raw materials
Preparation Products
Val-cit-PAB-OH Suppliers
- Tel
- 03-36680489
- Fax
- 03-3668-0520
- Sales-JP@TCIchemicals.com
- Country
- Japan
- ProdList
- 28398
- Advantage
- 80
View Lastest Price from Val-cit-PAB-OH manufacturers
- Product
- Val-Cit-PAB-OH 159857-79-1
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >95.00%
- Supply Ability
- 5g
- Release date
- 2024-03-29
- Product
- Val-cit-PAB-OH 159857-79-1
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-13
- Product
- Val-cit-PAB-OH 159857-79-1
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- ≥98%
- Supply Ability
- g/kg/Ton
- Release date
- 2020-03-05