Ethanone, 1-(4-bromophenyl)-2-[[5-(4-pyridinyl)-1,3,4-oxadiazol-2-yl]thio]-

Product Name: Ethanone, 1-(4-bromophenyl)-2-[[5-(4-pyridinyl)-1,3,4-oxadiazol-2-yl]thio]-
CAS No.: 491839-65-7
Chemical Name: Ethanone, 1-(4-bromophenyl)-2-[[5-(4-pyridinyl)-1,3,4-oxadiazol-2-yl]thio]-
Synonyms: FAK-IN-10;WAY-320461;Ethanone, 1-(4-bromophenyl)-2-[[5-(4-pyridinyl)-1,3,4-oxadiazol-2-yl]thio]-;1-(4-Bromophenyl)-2-((5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)thio)ethan-1-one;1-(4-Bromophenyl)-2-((5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)thio)ethan-1-one , FAK-IN-10
CBNumber: CB010696675
Molecular Formula: C15H10BrN3O2S
Formula Weight: 376.23
MOL File: 491839-65-7.mol

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Ethanone, 1-(4-bromophenyl)-2-[[5-(4-pyridinyl)-1,3,4-oxadiazol-2-yl]thio]- Property

Boiling point:: 570.1±60.0 °C(Predicted)
Density: 1.65±0.1 g/cm3(Predicted)
pka: 0.93±0.10(Predicted)
form: Solid
color: Light yellow to khaki

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Hazard and Precautionary Statements (GHS)

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Ethanone, 1-(4-bromophenyl)-2-[[5-(4-pyridinyl)-1,3,4-oxadiazol-2-yl]thio]- Chemical Properties,Usage,Production

Uses

FAK-IN-10 is an inhibitor of FAK with an IC50 of 76.3 μM. FAK-IN-10 exhibits antitumor activity against MCF-7 and A431 cell lines with IC50s of 4.23 and 0.78 μM,respectively[1].

References

[1] Zhang LR, et al. Synthesis, biological evaluation and molecular docking studies of novel 2-(1,3,4-oxadiazol-2-ylthio)-1-phenylethanone derivatives. Bioorg Med Chem. 2012 Jun 1;20(11):3615-21. DOI:10.1016/j.bmc.2012.03.061

Ethanone, 1-(4-bromophenyl)-2-[[5-(4-pyridinyl)-1,3,4-oxadiazol-2-yl]thio]- Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethanone, 1-(4-bromophenyl)-2-[[5-(4-pyridinyl)-1,3,4-oxadiazol-2-yl]thio]- Suppliers

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491839-65-7, Ethanone, 1-(4-bromophenyl)-2-[[5-(4-pyridinyl)-1,3,4-oxadiazol-2-yl]thio]-Related Search:

2H-Indol-2-one, 1,3-dihydro-3-[(5-methyl-2-furanyl)methylene]- N-[2-[4-(2-METHOXYPHENYL)-1-PIPERAZINYL]ETHYL]-N-2-PYRIDINYL-CYCLOHEXANECARBOXAMIDE MALEATE 1-(1,3-benzodioxol-5-ylmethyl)-4-[(3,4-dimethoxyphenyl)sulfonyl]piperazine Benzamide, N-(4-iodophenyl)-4-(4-morpholinylmethyl)- N-(4-chlorophenyl)-2-(thiophen-2-yl)acetamide (4-benzylpiperidin-1-yl)(4-fluorophenyl)methanone 3-(3,5-dimethyl-1H-pyrazol-1-yl)-N-(4-methylphenyl)propanamide 5-(3-bromophenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione N-(6-bromobenzo[d]thiazol-2-yl)cyclohexanecarboxamide 1-(4-fluorobenzoyl)-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine Benzamide, N-methyl-4-phenoxy-N-(phenylmethyl)- Benzenesulfonamide, N,N'-1,2-ethanediylbis[3-methyl- Acetamide, N-1H-benzimidazol-2-yl-2-phenoxy- WAY-234759 3-chloro-4-morpholin-4-yl-1-phenylpyrrole-2,5-dione 2-(1,3-benzoxazol-2-ylsulfanyl)-N-phenylacetamide 2-benzylsulfanyl-5-(4-methylphenyl)-1,3,4-oxadiazole N-(4-(1H-benzo[d]imidazol-2-yl)phenyl)-3,4,5-trimethoxybenzamide

Ethanone, 1-(4-bromophenyl)-2-[[5-(4-pyridinyl)-1,3,4-oxadiazol-2-yl]thio]-

WAY-320461

FAK-IN-10

1-(4-Bromophenyl)-2-((5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)thio)ethan-1-one , FAK-IN-10

1-(4-Bromophenyl)-2-((5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)thio)ethan-1-one

491839-65-7