3-chloro-4-morpholin-4-yl-1-phenylpyrrole-2,5-dione

Product Name: 3-chloro-4-morpholin-4-yl-1-phenylpyrrole-2,5-dione
CAS No.: 103056-35-5
Chemical Name: 3-chloro-4-morpholin-4-yl-1-phenylpyrrole-2,5-dione
Synonyms: WAY-298516;3-chloro-4-morpholin-4-yl-1-phenylpyrrole-2,5-dione;3-Chloro-4-morpholino-1-phenyl-1H-pyrrole-2,5-dione;1H-Pyrrole-2,5-dione, 3-chloro-4-(4-morpholinyl)-1-phenyl-
CBNumber: CB14579521
Molecular Formula: C14H13ClN2O3
Formula Weight: 292.72
MOL File: 103056-35-5.mol

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3-chloro-4-morpholin-4-yl-1-phenylpyrrole-2,5-dione Property

Melting point:: 160-161 °C
Boiling point:: 402.3±45.0 °C(Predicted)
Density: 1.45±0.1 g/cm3(Predicted)
pka: -3.33±0.60(Predicted)

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Hazard and Precautionary Statements (GHS)

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3-chloro-4-morpholin-4-yl-1-phenylpyrrole-2,5-dione Chemical Properties,Usage,Production

Uses

RAD51-IN-9 (Compound 3a) is a RAD51 inhibitor that can inhibit the binding of RAD51 to ssDNA with an IC50 of 17.85 μM. RAD51-IN-9 has a LD50 against HEK293 cells of 40.21 μM. RAD51-IN-9 can sensitize cells to Mitomycin C (HY-13316)[1].

References

[1] Budke B, et al. An optimized RAD51 inhibitor that disrupts homologous recombination without requiring Michael acceptor reactivity. J Med Chem. 2013 Jan 10;56(1):254-63. DOI:10.1021/jm301565b

3-chloro-4-morpholin-4-yl-1-phenylpyrrole-2,5-dione Preparation Products And Raw materials

Raw materials

Preparation Products

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3-chloro-4-morpholin-4-yl-1-phenylpyrrole-2,5-dione Suppliers

China 5 Finland 1 Ukraine 1 United States 1 Global 8

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103056-35-5, 3-chloro-4-morpholin-4-yl-1-phenylpyrrole-2,5-dioneRelated Search:

2H-Indol-2-one, 1,3-dihydro-3-[(5-methyl-2-furanyl)methylene]- N-[2-[4-(2-METHOXYPHENYL)-1-PIPERAZINYL]ETHYL]-N-2-PYRIDINYL-CYCLOHEXANECARBOXAMIDE MALEATE 1-(1,3-benzodioxol-5-ylmethyl)-4-[(3,4-dimethoxyphenyl)sulfonyl]piperazine N-(4-chlorophenyl)-2-(thiophen-2-yl)acetamide (4-benzylpiperidin-1-yl)(4-fluorophenyl)methanone Benzamide, N-(4-iodophenyl)-4-(4-morpholinylmethyl)- Ethanone, 1-(4-bromophenyl)-2-[[5-(4-pyridinyl)-1,3,4-oxadiazol-2-yl]thio]- 3-(3,5-dimethyl-1H-pyrazol-1-yl)-N-(4-methylphenyl)propanamide 5-(3-bromophenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione N-(6-bromobenzo[d]thiazol-2-yl)cyclohexanecarboxamide 1-(4-fluorobenzoyl)-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine Benzamide, N-methyl-4-phenoxy-N-(phenylmethyl)- Benzenesulfonamide, N,N'-1,2-ethanediylbis[3-methyl- Acetamide, N-1H-benzimidazol-2-yl-2-phenoxy- WAY-234759 2-(1,3-benzoxazol-2-ylsulfanyl)-N-phenylacetamide 2-benzylsulfanyl-5-(4-methylphenyl)-1,3,4-oxadiazole 2H-1,4-Benzoxazin-3(4H)-one, 6-[2-[(1,6-dihydro-4-methyl-6-oxo-2-pyrimidinyl)thio]acetyl]-

3-chloro-4-morpholin-4-yl-1-phenylpyrrole-2,5-dione

WAY-298516

3-Chloro-4-morpholino-1-phenyl-1H-pyrrole-2,5-dione

1H-Pyrrole-2,5-dione, 3-chloro-4-(4-morpholinyl)-1-phenyl-

103056-35-5