Ethyl Succinyl Chloride
- Product Name
- Ethyl Succinyl Chloride
- CAS No.
- 14794-31-1
- Chemical Name
- Ethyl Succinyl Chloride
- Synonyms
- Ethyl 4-chloro-4-oxobutanoate;Ethyl succinoyl chloride;ETHYL 4-CHLORO-4-OXOBUTYRATE;Butanoic acid, 4-chloro-4-oxo-, ethyl ester;SKL1293;oro-4-oxobutyrate;ETHYL SUCCINYL CHLORIDE;Ethyl siccinyl chloride;ETHYLSS-BENZOYLACRYLATE;EthylSuccinylChloride>
- CBNumber
- CB0107033
- Molecular Formula
- C6H9ClO3
- Formula Weight
- 164.59
- MOL File
- 14794-31-1.mol
Ethyl Succinyl Chloride Property
- Boiling point:
- 88-90 °C11 mm Hg(lit.)
- Density
- 1.155 g/mL at 25 °C(lit.)
- vapor pressure
- 48.2Pa at 25℃
- refractive index
- n20/D 1.437(lit.)
- Flash point:
- 184 °F
- storage temp.
- 2-8°C
- solubility
- soluble in Chloroform, Ethyl Acetate
- form
- Liquid
- Specific Gravity
- 1.144 to 1.17
- color
- Clear colorless to yellow
- Water Solubility
- 59.01g/L at 25℃
- Sensitive
- Moisture Sensitive
- BRN
- 1766126
- InChIKey
- IXZFDJXHLQQSGQ-UHFFFAOYSA-N
- LogP
- 0.05
- CAS DataBase Reference
- 14794-31-1(CAS DataBase Reference)
- NIST Chemistry Reference
- Butanoic acid, 4-chloro-4-oxo-, ethyl ester(14794-31-1)
- EPA Substance Registry System
- Butanoic acid, 4-chloro-4-oxo-, ethyl ester (14794-31-1)
Safety
- Hazard Codes
- C
- Risk Statements
- 34-36/37-14
- Safety Statements
- 26-27-36/37/39-45-24/25
- RIDADR
- UN 3265 8/PG 2
- WGK Germany
- 3
- TSCA
- Yes
- HazardClass
- 8
- PackingGroup
- II
- HS Code
- 29171990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P363Wash contaminated clothing before reuse.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 190705
- Product name
- Ethyl 4-chloro-4-oxobutyrate
- Purity
- 95%
- Packaging
- 25g
- Price
- $68.2
- Updated
- 2025/07/31
- Product number
- 190705
- Product name
- Ethyl 4-chloro-4-oxobutyrate
- Purity
- 95%
- Packaging
- 100g
- Price
- $178
- Updated
- 2025/07/31
- Product number
- E0368
- Product name
- Ethyl Succinyl Chloride
- Purity
- >95.0%(T)
- Packaging
- 25g
- Price
- $87
- Updated
- 2025/07/31
- Product number
- E0368
- Product name
- Ethyl Succinyl Chloride
- Purity
- >95.0%(T)
- Packaging
- 500g
- Price
- $447
- Updated
- 2025/07/31
- Product number
- E818230
- Product name
- EthylSuccinoylChloride
- Packaging
- 50g
- Price
- $100
- Updated
- 2021/12/16
Ethyl Succinyl Chloride Chemical Properties,Usage,Production
Chemical Properties
clear colourless to yellow liquid
Uses
Ethyl 4-chloro-4-oxobutyrate was used in the synthesis of:
- polymer-supported bifunctional catalyst
- succinimidyl ester of benzo(a)pyrene
- succinate prodrugs of curcuminoids
Flammability and Explosibility
Not classified
Synthesis
1070-34-4
14794-31-1
The general procedure for the synthesis of monoethyl succinate chloride from monoethyl succinate: monoethyl succinate (116.8 g, 0.8 mol), dichloromethane (300 mL) and thionyl chloride (104 g, 0.88 mol) were added to a reaction flask, N,N-dimethylformamide (0.8 g) was added under nitrogen protection, and heated and stirred by refluxing for 5 hours at 38°C. The reaction was completed with a solution of dichloromethane (124 g, 0.88 mol). Upon completion of the reaction, a dichloromethane solution of monoethylsuccinic acid chloride (124 g, yield: 95%) was obtained.
References
[1] Heterocycles, 2001, vol. 55, # 8, p. 1487 - 1498
[2] Journal of Medicinal Chemistry, 2007, vol. 50, # 7, p. 1528 - 1536
[3] Patent: CN104326922, 2016, B. Location in patent: Paragraph 0038; 0040
[4] Journal of the American Chemical Society, 1991, vol. 113, # 6, p. 2071 - 2092
[5] Journal of Organic Chemistry, 1996, vol. 61, # 14, p. 4848 - 4852
Ethyl Succinyl Chloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Ethyl Succinyl Chloride manufacturers
- Product
- Ethyl Succinyl Chloride 14794-31-1
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-15
- Product
- Ethyl Succinyl Chloride 14794-31-1
- Price
- US $5.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10000
- Release date
- 2024-08-08
- Product
- Ethyl Succinyl Chloride 14794-31-1
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-11-04