ChemicalBook > CAS DataBase List > Ethyl Succinyl Chloride

Ethyl Succinyl Chloride

Product Name
Ethyl Succinyl Chloride
CAS No.
14794-31-1
Chemical Name
Ethyl Succinyl Chloride
Synonyms
Ethyl 4-chloro-4-oxobutanoate;Ethyl succinoyl chloride;ETHYL 4-CHLORO-4-OXOBUTYRATE;Butanoic acid, 4-chloro-4-oxo-, ethyl ester;SKL1293;oro-4-oxobutyrate;ETHYL SUCCINYL CHLORIDE;Ethyl siccinyl chloride;ETHYLSS-BENZOYLACRYLATE;EthylSuccinylChloride>
CBNumber
CB0107033
Molecular Formula
C6H9ClO3
Formula Weight
164.59
MOL File
14794-31-1.mol
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Ethyl Succinyl Chloride Property

Boiling point:
88-90 °C11 mm Hg(lit.)
Density 
1.155 g/mL at 25 °C(lit.)
vapor pressure 
48.2Pa at 25℃
refractive index 
n20/D 1.437(lit.)
Flash point:
184 °F
storage temp. 
2-8°C
solubility 
soluble in Chloroform, Ethyl Acetate
form 
Liquid
Specific Gravity
1.144 to 1.17
color 
Clear colorless to yellow
Water Solubility 
59.01g/L at 25℃
Sensitive 
Moisture Sensitive
BRN 
1766126
InChIKey
IXZFDJXHLQQSGQ-UHFFFAOYSA-N
LogP
0.05
CAS DataBase Reference
14794-31-1(CAS DataBase Reference)
NIST Chemistry Reference
Butanoic acid, 4-chloro-4-oxo-, ethyl ester(14794-31-1)
EPA Substance Registry System
Butanoic acid, 4-chloro-4-oxo-, ethyl ester (14794-31-1)
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Safety

Hazard Codes 
C
Risk Statements 
34-36/37-14
Safety Statements 
26-27-36/37/39-45-24/25
RIDADR 
UN 3265 8/PG 2
WGK Germany 
3
TSCA 
Yes
HazardClass 
8
PackingGroup 
II
HS Code 
29171990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
190705
Product name
Ethyl 4-chloro-4-oxobutyrate
Purity
95%
Packaging
25g
Price
$68.2
Updated
2025/07/31
Sigma-Aldrich
Product number
190705
Product name
Ethyl 4-chloro-4-oxobutyrate
Purity
95%
Packaging
100g
Price
$178
Updated
2025/07/31
TCI Chemical
Product number
E0368
Product name
Ethyl Succinyl Chloride
Purity
>95.0%(T)
Packaging
25g
Price
$87
Updated
2025/07/31
TCI Chemical
Product number
E0368
Product name
Ethyl Succinyl Chloride
Purity
>95.0%(T)
Packaging
500g
Price
$447
Updated
2025/07/31
TRC
Product number
E818230
Product name
EthylSuccinoylChloride
Packaging
50g
Price
$100
Updated
2021/12/16
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Ethyl Succinyl Chloride Chemical Properties,Usage,Production

Chemical Properties

clear colourless to yellow liquid

Uses

Ethyl 4-chloro-4-oxobutyrate was used in the synthesis of:

  • polymer-supported bifunctional catalyst
  • succinimidyl ester of benzo(a)pyrene
  • succinate prodrugs of curcuminoids

Flammability and Explosibility

Not classified

Synthesis

1070-34-4

14794-31-1

The general procedure for the synthesis of monoethyl succinate chloride from monoethyl succinate: monoethyl succinate (116.8 g, 0.8 mol), dichloromethane (300 mL) and thionyl chloride (104 g, 0.88 mol) were added to a reaction flask, N,N-dimethylformamide (0.8 g) was added under nitrogen protection, and heated and stirred by refluxing for 5 hours at 38°C. The reaction was completed with a solution of dichloromethane (124 g, 0.88 mol). Upon completion of the reaction, a dichloromethane solution of monoethylsuccinic acid chloride (124 g, yield: 95%) was obtained.

References

[1] Heterocycles, 2001, vol. 55, # 8, p. 1487 - 1498
[2] Journal of Medicinal Chemistry, 2007, vol. 50, # 7, p. 1528 - 1536
[3] Patent: CN104326922, 2016, B. Location in patent: Paragraph 0038; 0040
[4] Journal of the American Chemical Society, 1991, vol. 113, # 6, p. 2071 - 2092
[5] Journal of Organic Chemistry, 1996, vol. 61, # 14, p. 4848 - 4852

Ethyl Succinyl Chloride Preparation Products And Raw materials

Raw materials

Succinic anhydride

Preparation Products

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Ethyl Succinyl Chloride Suppliers

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View Lastest Price from Ethyl Succinyl Chloride manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
Ethyl Succinyl Chloride 14794-31-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-05-15
Hebei Fengjia New Material Co., Ltd
Product
Ethyl Succinyl Chloride 14794-31-1
Price
US $5.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10000
Release date
2024-08-08
Hebei Chuanghai Biotechnology Co., Ltd
Product
Ethyl Succinyl Chloride 14794-31-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-04

14794-31-1, Ethyl Succinyl ChlorideRelated Search:

Butyryl chloride Diisopropyl succinate 4-CHLOROBUTYRIC ACID Sodium propionate SUCCINALDEHYDIC ACID SUCCINALDEHYDE Methyl 4-chlorobutyrate 1-Chlorobutane Methyl 4-chloro-4-oxobutanoate Methyl 4-oxobutanoate Methyl butyrate Butyl ethyl ether Ethyl Succinyl Chloride 1-Propanol ETHYL 4-CHLOROBUTYRATE 1-Butanol Butyric Acid 4-Chlorobutyl methyl ether

  • BETA CARBETHOXY PROPIONYL CHLORIDE
  • ETHYL SUCCINYL CHLORIDE
  • ETHYL 4-CHLORO-4-OXOBUTYRATE
  • ETHYL 3-(CHLOROFORMYL)PROPIONATE
  • Ethyl siccinyl chloride
  • ETHYL 4-CHLORO-4-OXOBUTYRATE,95%
  • Ethyl succinyl chloride, tech., 95%
  • 3-CARBETHOXYPROPIONYL CHLORIDE (Ethyl Succinyl Chloride)
  • 3-Carbethoxypropionyl chloride
  • 3-Ethoxycarbonylpropionyl chloride
  • SUCCINIC ACID MONOETHYL ESTER CHLORIDE
  • 3-Carboethoxypropionyl chloride
  • 4-chloro-4-oxo-butanoicaciethylester
  • beta-Ethoxycarbonylpropionyl chloride
  • Ethyl 4-chloro-4-oxobutanoate
  • Ethyl succinoyl chloride
  • Propionic acid, 3-(chloroformyl)-, ethyl ester
  • 2-ethylbutanedioyl dichloride
  • Monoethyl succinyl chloride
  • Butanoic acid, 4-chloro-4-oxo-, ethyl ester
  • 4-chloro-4-oxo-butanoic acid ethyl ester
  • -Carbethoxy propionyl chloride
  • 3-(Ethoxycarbonyl)propanoyl chloride
  • (Succinic acid 1-ethyl) chloride
  • 3-(Chloroformyl)propionic acid ethyl ester
  • 4-Chloro-4-oxobutyric acid ethyl ester
  • 4-Oxo-4-chlorobutanoic acid ethyl ester
  • 4-Oxo-4-chlorobutyric acid ethyl ester
  • ETHYLSS-BENZOYLACRYLATE
  • Ethyl succinyl chloride,98%
  • Ethyl 4-chloro-4-oxobutyrate, 95.0%(T)
  • Ethyl succinyl chloride(ESC)
  • Ethyl 4-chloro-4-oxobutyrate 95%
  • Ethyl succinyl chloride, 95&percnt:
  • Succinic acid ethyl ester chloride
  • EthylSuccinylChloride&gt
  • oro-4-oxobutyrate
  • SKL1293
  • TIANFU-CHEM Ethyl 3-(chloroformyl)propionate 14794-31-1
  • ETHYL SUCCINYL CHLORIDE Extra Pure
  • Monoethyl succinate chloride
  • 14794-31-1
  • 14794-31-3
  • ClCOCH2CH2CO2C2H5
  • ClOCCH2CH2CO2CH2CH3
  • C6H9ClO3
  • Carbonyl Compounds
  • Building Blocks
  • ACID CHLORIDE
  • Acid Halides
  • Organic Building Blocks
  • bc0001