4,6-Dichloropyridine-3-acetonitrile

Product Name: 4,6-Dichloropyridine-3-acetonitrile
CAS No.: 199283-52-8
Chemical Name: 4,6-Dichloropyridine-3-acetonitrile
Synonyms: 3-Pyridineacetonitrile, 4,6-dichloro-;2-(4,6-Dichloro-3-pyridyl)acetonitrile;(4,6-Dichloro-3-Pyridinyl)Acetonitrile;2-(4,6-DICHLOROPYRIDIN-3-YL)ACETONITRILE
CBNumber: CB01074150
Molecular Formula: C7H4Cl2N2
Formula Weight: 187.03
MOL File: 199283-52-8.mol

More

Less

4,6-Dichloropyridine-3-acetonitrile Property

Boiling point:: 315.3±37.0 °C(Predicted)
Density: 1.408±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: -0.47±0.10(Predicted)
Appearance: White to yellow Solid

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

AK Scientific

Product number: 4386CH
Product name: 2-(4,6-Dichloropyridin-3-yl)acetonitrile
Packaging: 1g
Price: $875
Updated: 2021/12/16

Crysdot

Product number: CD11170279
Product name: 2-(4,6-Dichloropyridin-3-yl)acetonitrile
Purity: 95+%
Packaging: 250mg
Price: $230
Updated: 2021/12/16

Chemenu

Product number: CM251007
Product name: 2-(4,6-Dichloropyridin-3-yl)acetonitrile
Purity: 95%
Packaging: 1g
Price: $542
Updated: 2021/12/16

Crysdot

Product number: CD11170279
Product name: 2-(4,6-Dichloropyridin-3-yl)acetonitrile
Purity: 95+%
Packaging: 1g
Price: $574
Updated: 2021/12/16

Acrotein

Product number: UT00417
Product name: 2-(4,6-Dichloropyridin-3-yl)acetonitrile
Purity: 97%
Packaging: 1g
Price: $739.42
Updated: 2021/12/16

More

Less

4,6-Dichloropyridine-3-acetonitrile Chemical Properties,Usage,Production

Synthesis

7677-24-9

1227606-01-0

199283-52-8

Step 2: 5-(bromomethyl)-2,4-dichloropyridine (0.500 g, 1.87 mmol) was dissolved in acetonitrile (5.0 mL). To this solution was added sodium hydroxide monohydrate (UOH-H2O, 0.0960 g, 2.24 mmol) followed by slow dropwise addition of trimethylcyanosilane (0.280 mL, 2.24 mmol). The reaction mixture was stirred continuously at room temperature for 2 hours. After completion of the reaction, the reaction solution was diluted with ethyl acetate. The diluted solution was washed twice with water. The organic phase was dried over anhydrous sodium sulfate, then the filtrate was filtered and concentrated to give a yellow oily crude product (394 mg). The crude product was purified by fast column chromatography (eluent: cyclohexane/ethyl acetate, 4:1) to afford the target product 2-(4,6-dichloropyridin-3-yl)acetonitrile (329 mg) in white solid form. The product was characterized by 1H-NMR (CDCl3): δ 8.5 (s, 1H), 7.47 (s, 1H), 3.82 (s, 2H).

References

[1] Patent: WO2013/64521, 2013, A1. Location in patent: Page/Page column 110

4,6-Dichloropyridine-3-acetonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

4,6-Dichloropyridine-3-acetonitrile Suppliers

China 16 Germany 1 India 1 United States 1 Global 19

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19913
Advantage: 55

ShangHai KenEn Chemical Technology Co., Ltd.

Tel: 13120367189
Fax: 021-50315529
Email: mychess007@163.com
Country: China
ProdList: 1994
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Cochemical Ltd.

Tel: 029-86115547 17791676824
Fax: 021-51602123
Email: sales@cochemical.com
Country: China
ProdList: 4006
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Shanghai Kaiwei Chemical Technology Co., Ltd.

Tel: 021-58461859 15821823057
Email: service@aiviche.com
Country: China
ProdList: 49312
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

Xi'an Zhenghao Biotechnology Co., Ltd

Tel: 19829389091
Fax: QQ:399787610
Email: 399787610@qq.com
Country: China
ProdList: 2575
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39653
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50464
Advantage: 58

Shanghai Ken chemical Technology Co.,ltd

Tel: 02152215958
Email: 47697177@qq.com
Country: China
ProdList: 10011
Advantage: 58

Zhengzhou Allchem Chemical Co., Ltd

Tel: 17734807184; 17734807184
Email: 3805691809@qq.com
Country: China
ProdList: 6433
Advantage: 58

DAYANG CHEM (HANGZHOU) CO.,LTD

Tel: +86-88938639 +86-17705817739
Email: info@dycnchem.com
Country: China
ProdList: 53899
Advantage: 58

Cochemical Co. Ltd.

Tel: +86-029-86115547 +86-17791676824
Email: sales@cochemical.com
Country: China
ProdList: 3952
Advantage: 58

Jilin Chinese Academy of Sciences-yanshen Technology

Tel: +undefined18143011203
Email: info@chemextension.com
Country: China
ProdList: 42056
Advantage: 58

199283-52-8, 4,6-Dichloropyridine-3-acetonitrileRelated Search:

Pyridine 2,4-Dichloro-5-methylpyridine 3-PYRIDYLACETONITRILE 2-Chloro-5-pyridineacetonitrile 4,6-Dichloropyridine-3-acetonitrile

(4,6-Dichloro-3-Pyridinyl)Acetonitrile

2-(4,6-DICHLOROPYRIDIN-3-YL)ACETONITRILE

3-Pyridineacetonitrile, 4,6-dichloro-

2-(4,6-Dichloro-3-pyridyl)acetonitrile

199283-52-8