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LY288513

Product Name
LY288513
CAS No.
147523-65-7
Chemical Name
LY288513
Synonyms
LY288513;LY-288513,LY288513;(4S,5R)-N-(4-Bromophenyl)-3-oxo-4,5-diphenyl-1-pyrazolidinecarboxamide;1-Pyrazolidinecarboxamide, N-(4-bromophenyl)-3-oxo-4,5-diphenyl-, (4S,5R)-
CBNumber
CB01075122
Molecular Formula
C22H18BrN3O2
Formula Weight
436.3
MOL File
147523-65-7.mol
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LY288513 Property

Melting point:
120-122°C
storage temp. 
Store at +4°C
solubility 
DMSO (Slightly), Methanol (Very Slightly)
form 
Solid
color 
White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
1524
Product name
LY288513
Purity
≥98%(HPLC)
Packaging
10
Price
$338
Updated
2021/12/16
Tocris
Product number
1524
Product name
LY288513
Purity
≥98%(HPLC)
Packaging
50
Price
$1374
Updated
2021/12/16
TRC
Product number
L503168
Product name
LY288513
Packaging
1mg
Price
$180
Updated
2021/12/16
ApexBio Technology
Product number
B5125
Product name
LY288513
Packaging
10mg
Price
$480
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
BRS0000553
Product name
LY 288513
Purity
95.00%
Packaging
10MG
Price
$794.36
Updated
2021/12/16
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LY288513 Chemical Properties,Usage,Production

Uses

LY 288513 is a CCK-B antagonist, which blocks the effects of nicotine withdrawal on auditory startle.

Definition

ChEBI: (4S,5R)-N-(4-bromophenyl)-3-oxo-4,5-diphenyl-1-pyrazolidinecarboxamide is a stilbenoid.

Biological Activity

Selective CCK 2 receptor antagonist (IC 50 values are 16 and > 30,000 nM for CCK 2 and CCK 1 respectively). Displays anxiolytic and antipsychotic properties in vivo .

in vivo

LY288513 (3, 10 mg/kg, i.p.; 10, 30 mg/kg, p.o.) produces an anxiolytic-like action in mice[3].
LY288513 (1000 mg/kg, p.o.) potentiates the effects of a CNS depressant, slightly lowered body temperature, and had modest sedative effects only at the highest dose examined[3].

Animal Model:Male CD-l mice[3]
Dosage:3, 10 mg/kg; 10, 30 mg/kg
Administration:I.p.; p.o.
Result:Displayed anxiolytic-like effects in the elevated plusmaze.

storage

Store at +4°C

LY288513 Preparation Products And Raw materials

Raw materials

Preparation Products

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LY288513 Suppliers

CHINA 18 Germany 1 United Kingdom 1 United States 6 USA 1 Global 27
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
Advantage
58
Nantong QuanYi Biotechnology Co., Ltd
Tel
0513-66337626 18051384581
Email
sales@chemhifuture.com
Country
China
ProdList
5929
Advantage
58
Shanghai Fine Biotech Co.，Ltd
Tel
18221172427
Email
sale@fine-biotech.com
Country
China
ProdList
2753
Advantage
58
R&D Systems, Inc
Tel
18003437475
Fax
1-612-656-4400
Email
rdname@qq.com
Country
China
ProdList
6960
Advantage
58
Biosynth Biological Technology (Suzhou) Co Ltd
Tel
51288865780
Email
sales@biosynth.com
Country
China
ProdList
6051
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58
Wuhan Topule Biopharmaceutical Co., Ltd
Tel
+8618327326525
Email
masar@topule.com
Country
China
ProdList
8467
Advantage
58

147523-65-7, LY288513Related Search:

(1,2-DIPHENYL-ETHYL)-HYDRAZINE LY288513 ALPHA-BROMOISOBUTYRIC ACID

  • LY288513
  • (4S,5R)-N-(4-Bromophenyl)-3-oxo-4,5-diphenyl-1-pyrazolidinecarboxamide
  • 1-Pyrazolidinecarboxamide, N-(4-bromophenyl)-3-oxo-4,5-diphenyl-, (4S,5R)-
  • LY-288513,LY288513
  • 147523-65-7