ChemicalBook > CAS DataBase List > Alibendol

Alibendol

Product Name
Alibendol
CAS No.
26750-81-2
Chemical Name
Alibendol
Synonyms
fc54;PC-54;H-3774;Cebera;EB 1856;Ailbendol;ALIBENDOL;Alibendol powder;Alibendol USP/EP/BP;5-allyl-2-hydroxy-n-(2-hydroxyethyl)-m-anisamid
CBNumber
CB0108681
Molecular Formula
C13H17NO4
Formula Weight
251.28
MOL File
26750-81-2.mol
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Alibendol Property

Melting point:
97-99°C
Boiling point:
402.4±45.0 °C(Predicted)
Density 
1.192±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO, Methanol
form 
Solid
pka
8.59±0.48(Predicted)
color 
White
λmax
316nm(EtOH)(lit.)
Merck 
14,244
CAS DataBase Reference
26750-81-2(CAS DataBase Reference)
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Safety

RTECS 
CU8730000
HS Code 
2924.29.7790
Toxicity
LD50 in Swiss male mice (mg/kg): >3000 orally; >2000 s.c.; 209 i.p.; 217 i.v. (Clémence)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TCI Chemical
Product number
A2965
Product name
Alibendol
Purity
>98.0%(GC)
Packaging
1g
Price
$16
Updated
2024/03/01
TCI Chemical
Product number
A2965
Product name
Alibendol
Purity
>98.0%(GC)
Packaging
5g
Price
$41
Updated
2024/03/01
TRC
Product number
A535930
Product name
Alibendol
Packaging
50mg
Price
$60
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA17279
Product name
Alibendol
Packaging
100mg
Price
$100.5
Updated
2021/12/16
Chem-Impex
Product number
37614
Product name
Alibendol,98%(GC)
Purity
98%(GC)
Packaging
5G
Price
$143.36
Updated
2021/12/16
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Alibendol Chemical Properties,Usage,Production

Chemical Properties

White Solid

Originator

Cebera ,Bouchara ,France ,1981

Uses

An amide analog of Eugenol, and is used therapeutically as an antispasmodic.

Uses

Alibendol is an antispasmodic,choleretic, and cholekinetic.

Definition

ChEBI: Alibendol is a member of salicylamides.

Manufacturing Process

36 g of ethyl ester of 2-hydroxy-3-methoxy-5-allyl-benzoic acid [obtained by the process described by Pearl, et al., J. Amer. Chem. Soc., Vol. 71, 1067- 1068 (1949)] and 61 g of ethanolamine were admixed and left to stand for 1 hour at ambient temperature after which it was heated for 1 hour at 120°C. The mixture was extracted with chloroform and the organic phases were washed with half diluted hydrochloric acid, then with water, and the chloroform evaporated off. The residue, after recrystallization from benzene, was a 78% yield of 2-hydroxy-3-methoxy-5-allyl-N-(β-hydroxyethyl)- benzamide having a melting point of 95°C. The product appeared in the form of colorless crystals which were insoluble in water and soluble in dilute sodium hydroxide.

Therapeutic Function

Choleretic, Spasmolytic

Alibendol Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Alibendol manufacturers

Hebei Shengyuan Jinlong Import and Export Co. LTD
Product
Alibendol 26750-81-2
Price
US $10.00-5.00/kg
Min. Order
1kg
Purity
99
Supply Ability
500ton/month
Release date
2022-10-27
Shanxi Naipu Import and Export Co.,Ltd
Product
Alibendol 26750-81-2
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500ton/month
Release date
2020-12-29
Hebei Zhanyao Biotechnology Co. Ltd
Product
Alibendol powder 26750-81-2
Price
US $60.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000
Release date
2021-08-20

26750-81-2, AlibendolRelated Search:


  • hydroxy-2methoxy-3allyl-5n-(beta-hydroxyethyl)benzamide
  • Alibendol ,2-hydroxy-3-methoxy-5-allyl-N-(C-hydroxyethyl)-benzamide
  • 5-Allyl-2-hydroxy-N-(2-hydroxyethyl)-3-methoxybenzamide
  • 5-Allyl-N-(2-hydroxyethyl)-3-methoxysalicylamide
  • Cebera
  • H-3774
  • PC-54
  • 2-hydroxy-N-(2-hydroxyethyl)-3-methoxy-5-prop-2-enylbenzamide
  • 2-hydroxy-N-(2-hydroxyethyl)-3-methoxy-5-prop-2-enyl-benzamide
  • 2-Hydroxy-N-(2-hydroxyethyl)-3-Methoxy-5-(2-propen-1-yl)benzaMide
  • 5-Allyl-2-hydroxy-N-(2-hydroxyethyl)-M-anisaMide
  • EB 1856
  • 5-allyl-2-hydroxy-n-(2-hydroxyethyl)-3-methoxy-benzamid
  • 5-allyl-2-hydroxy-n-(2-hydroxyethyl)-m-anisamid
  • Ailbendol
  • fc54
  • ALIBENDOL
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  • Benzamide,2-hydroxy-N-(2-hydroxyethyl)-3-methoxy-5-(2-propen-1-yl)
  • Alibendol USP/EP/BP
  • Alibendol powder
  • 2-hydroxy-N-(2-hydroxyethyl)-3-methoxy-5-(prop-2-en-1-yl)benzamide
  • 26750-81-2
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