Description
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Chlorantraniliprole

Description
Product Name
Chlorantraniliprole
CAS No.
500008-45-7
Chemical Name
Chlorantraniliprole
Synonyms
CHLOANTRANILIPROLE;Clorantraniliprole;Chlorantranilipol;Chlorantraniliprole [iso];Chlorantraniliprole 35%WDG;3-Bromo-4-chloro-1-(3-chloro-2-pyridyl)-2-methyl-6-(methylcarbamoyl)pyrazole-5-carboxanilide;3-Bromo-N-[4-chloro-2-methyl-6-[(methylamino)carbonyl]phenyl]-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxamide;Coragen;Altacor;Rynaxpyr
CBNumber
CB01404014
Molecular Formula
C18H14BrCl2N5O2
Formula Weight
483.15
MOL File
500008-45-7.mol
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Chlorantraniliprole Property

Melting point:
approximate 225℃ (dec.)
Boiling point:
526.6±50.0 °C(Predicted)
Density 
1.66±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform: Slightly Soluble; DMSO: Slightly Soluble
form 
A solid
pka
10.19±0.70(Predicted)
color 
White to off-white
LogP
3.641 (est)
CAS DataBase Reference
500008-45-7
EPA Substance Registry System
1H-Pyrazole-5-carboxamide, 3-bromo-N-[4-chloro-2-methyl-6-[(methylamino)carbonyl]phenyl]-1-(3-chloro-2-pyridinyl)- (500008-45-7)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37
Safety Statements 
26
Hazardous Substances Data
500008-45-7(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
24140
Product name
Chlorantraniliprole
Packaging
10mg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
24140
Product name
Chlorantraniliprole
Packaging
25mg
Price
$109
Updated
2024/03/01
Cayman Chemical
Product number
24140
Product name
Chlorantraniliprole
Packaging
5mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
24140
Product name
Chlorantraniliprole
Packaging
50mg
Price
$184
Updated
2024/03/01
TRC
Product number
C325380
Product name
Chlorantraniliprole
Packaging
10g
Price
$1550
Updated
2021/12/16
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Chlorantraniliprole Chemical Properties,Usage,Production

Description

Chlorantraniliprole (Rynaxpyr) is an insecticide of the ryanoid class. It is a new compound by DuPont belonging to a new class of selective insecticides (anthranilic diamides) featuring a novel mode of action (group 28 in the IRAC classification). It is the first anthranilic diamide registered for use on turfgrass and landscape ornamentals. It is used to control a broad spectrum of pests including cabbage loopers, corn borers, Colorado potato beetle, European grapevine moth, armyworms and cutwormson a range of crops including potatoes and cotton. Its mechanism of action is through activating the insect ryanodine receptors (RyRs), further stimulating the release and depletion of intracellular calcium stores from the sarcoplasmic reticulum of muscle cells, causing impaired muscle regulation, paralysis and ultimately death of sensitive species.

Description

Chlorantraniliprole is an anthranilic diamide insecticide and agonist of ryanodine receptors located on the sarcoplasmic reticulum in muscle and endoplasmic reticulum in non-muscle cells. It binds to a different site than ryanodine on the receptor and stimulates the release of calcium from intracellular stores with EC50 values ranging from 40 to 50 nM for P. americana neurons and H. virescens or D. melanogaster recombinant ryanodine receptors. It is highly selective for insect over mammalian ryanodine receptors (EC50s = 14,000 nM, >100 μM, and >100 μM for C2C12 mouse, PC12 rat, and IMR32 human cells, respectively). Chlorantraniliprole is active against insects of the order Lepidoptera, including larvae of the fall armyworm (S. frugiperda), diamondback moth (P. xylostella), and tobacco budworm (H. virescens) with EC50 values of 0.02, 0.01, and 0.05 ppm, respectively, and of the orders Coleoptera, Diptera, and Isoptera. Formulations containing chlorantraniliprole have been used in agriculture to control moths, beetles, and caterpillars among other insects.

Chemical Properties

White crystal, specific gravity (for liquid) 1.507g/mL, melting point 208-210℃, decomposition temperature 330℃, vapor pressure (under 20~25) 6.3×1012Pa, solubility (under 20~25, mg/L): water 1.023, acetone 3.446, methanol 1.714, acetonitrile 0.711, ethyl acetate 1.144. Chlorfenvinphos It is highly efficient and broad-spectrum, and has good control effect on Lepidoptera of Noctuidae, stem borer moths, fruit moths, leaf roller moths, pink moths, vegetable moths, wheat moths, and fine moths, etc. It can also control Sphingidae weevils, leaf beetles; Diptera subterranean flies; sooty fly and many other non-lepidopteran pests.

Uses

Chlorantraniliprole is a pyrazolylpyridine insecticide and an activator of insect ryanodine receptor. Used in Pesticide detection. (Solution)

Definition

ChEBI: Chlorantraniliprole is a carboxamide resulting from the formal condensation of the carboxylic acid group of 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylic acid with the primary amino group of 2-amino-5-chloro-N,3-dimethylbenzamide. The first of the anthranilic diamide insecticides, it is a ryanodine receptor activator and is used to protect a wide variety of crops, including corn, cotton, grapes, rice and potatoes. It has a role as a ryanodine receptor agonist. It is an organobromine compound, a member of pyridines, a member of pyrazoles, a pyrazole insecticide, a member of monochlorobenzenes and a secondary carboxamide.

Preparation

Chlorantraniliprole was synthesized by reaction of 3-bromo-1-(3-chloropyridin-2-pyridinyl)-1H-pyrazole-5carboxylic acid with 2-amino-5-chloro-3-methylbenzoic acid.3-bromo-1-(3-chloropyridin-2-pyridinyl)-1H-pyrazole5-carboxylic acid was prepared by reaction of maleic anhydride with 2,3-dichloropyridine as starting materials in eight steps.2-Amino-5-chloro-3-methylbenzoic acid was prepared by reaction of 2-amino-3-methylbenzoic acid in one step.The structure of target compound was conf irmed by 1H NMR.Total yield was 36.3%(calculated with 2,3-dichloropyridine),and purity determined by HPLC was over 95%.

Chlorantraniliprole Preparation Products And Raw materials

Raw materials

Preparation Products

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Chlorantraniliprole Suppliers

wuxilvhuyuanshengwukejiyouxiangongsi
Tel
0813-18681388 18681388385
Email
wjf18861661468@petalmial.com
Country
China
ProdList
50
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58
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
Country
China
ProdList
3239
Advantage
55
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ:65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
7296
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58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Hubei Zhengxingyuan Fine Chemical Co., Ltd.
Tel
027-87879189 15207106154
Fax
027-87879189
Email
3386829764@qq.com
Country
China
ProdList
309
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58
Wuhan hongde yuexin pharmaceutical technology co. LTD
Tel
027-83855391 13657260109
Fax
027-83855391
Email
hbzlkschem2009@163.com
Country
China
ProdList
4200
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58
Wuhan xinyangruihe Chemical Technology Co., Ltd.
Tel
027-83850113 18171155316
Fax
027-83855316
Email
2821856175@qq.com
Country
China
ProdList
4724
Advantage
58
Jiangsu raspberry International Trade Co., Ltd.
Tel
18507340638
Email
2335663646@qq.com
Country
China
ProdList
197
Advantage
58
wuhan dingxingtong Chemical Technology Co., Ltd Co., Ltd
Tel
027-59207796 13429867250
Fax
027-59207796
Email
w13429867250@163.com
Country
China
ProdList
1989
Advantage
58
Wuhan Rongcan Biotechnology Co., Ltd
Tel
18327024450
Fax
183-27024450
Email
2130026275@qq.com
Country
China
ProdList
4570
Advantage
58
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View Lastest Price from Chlorantraniliprole manufacturers

qingdao trust agri chemical co.,ltd
Product
chlorantraniliprole 500008-45-7
Price
US $0.00/kg
Min. Order
1kg
Purity
99
Supply Ability
20tons
Release date
2024-08-06

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