Description
ChemicalBook > CAS DataBase List > Chlorantraniliprole

Chlorantraniliprole

Description
Product Name
Chlorantraniliprole
CAS No.
500008-45-7
Chemical Name
Chlorantraniliprole
Synonyms
CHLOANTRANILIPROLE;Clorantraniliprole;Chlorantranilipol;Chlorantraniliprole [iso];Chlorantraniliprole 35%WDG;3-Bromo-4-chloro-1-(3-chloro-2-pyridyl)-2-methyl-6-(methylcarbamoyl)pyrazole-5-carboxanilide;3-Bromo-N-[4-chloro-2-methyl-6-[(methylamino)carbonyl]phenyl]-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxamide;Coragen;Altacor;Rynaxpyr
CBNumber
CB01404014
Molecular Formula
C18H14BrCl2N5O2
Formula Weight
483.15
MOL File
500008-45-7.mol
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Chlorantraniliprole Property

Melting point:
approximate 225℃ (dec.)
Boiling point:
526.6±50.0 °C(Predicted)
Density 
1.66±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform: Slightly Soluble; DMSO: Slightly Soluble
form 
A solid
pka
10.19±0.70(Predicted)
LogP
3.641 (est)
CAS DataBase Reference
500008-45-7
EPA Substance Registry System
1H-Pyrazole-5-carboxamide, 3-bromo-N-[4-chloro-2-methyl-6-[(methylamino)carbonyl]phenyl]-1-(3-chloro-2-pyridinyl)- (500008-45-7)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37
Safety Statements 
26
Hazardous Substances Data
500008-45-7(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
24140
Product name
Chlorantraniliprole
Packaging
10mg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
24140
Product name
Chlorantraniliprole
Packaging
25mg
Price
$109
Updated
2024/03/01
Cayman Chemical
Product number
24140
Product name
Chlorantraniliprole
Packaging
5mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
24140
Product name
Chlorantraniliprole
Packaging
50mg
Price
$184
Updated
2024/03/01
TRC
Product number
C325380
Product name
Chlorantraniliprole
Packaging
10g
Price
$1550
Updated
2021/12/16
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Chlorantraniliprole Chemical Properties,Usage,Production

Description

Chlorantraniliprole (Rynaxpyr) is an insecticide of the ryanoid class. It is a new compound by DuPont belonging to a new class of selective insecticides (anthranilic diamides) featuring a novel mode of action (group 28 in the IRAC classification). It is the first anthranilic diamide registered for use on turfgrass and landscape ornamentals. It is used to control a broad spectrum of pests including cabbage loopers, corn borers, Colorado potato beetle, European grapevine moth, armyworms and cutwormson a range of crops including potatoes and cotton. Its mechanism of action is through activating the insect ryanodine receptors (RyRs), further stimulating the release and depletion of intracellular calcium stores from the sarcoplasmic reticulum of muscle cells, causing impaired muscle regulation, paralysis and ultimately death of sensitive species.

Description

Chlorantraniliprole is an anthranilic diamide insecticide and agonist of ryanodine receptors located on the sarcoplasmic reticulum in muscle and endoplasmic reticulum in non-muscle cells. It binds to a different site than ryanodine on the receptor and stimulates the release of calcium from intracellular stores with EC50 values ranging from 40 to 50 nM for P. americana neurons and H. virescens or D. melanogaster recombinant ryanodine receptors. It is highly selective for insect over mammalian ryanodine receptors (EC50s = 14,000 nM, >100 μM, and >100 μM for C2C12 mouse, PC12 rat, and IMR32 human cells, respectively). Chlorantraniliprole is active against insects of the order Lepidoptera, including larvae of the fall armyworm (S. frugiperda), diamondback moth (P. xylostella), and tobacco budworm (H. virescens) with EC50 values of 0.02, 0.01, and 0.05 ppm, respectively, and of the orders Coleoptera, Diptera, and Isoptera. Formulations containing chlorantraniliprole have been used in agriculture to control moths, beetles, and caterpillars among other insects.

Chemical Properties

White crystal, specific gravity (for liquid) 1.507g/mL, melting point 208-210℃, decomposition temperature 330℃, vapor pressure (under 20~25) 6.3×1012Pa, solubility (under 20~25, mg/L): water 1.023, acetone 3.446, methanol 1.714, acetonitrile 0.711, ethyl acetate 1.144. Chlorfenvinphos It is highly efficient and broad-spectrum, and has good control effect on Lepidoptera of Noctuidae, stem borer moths, fruit moths, leaf roller moths, pink moths, vegetable moths, wheat moths, and fine moths, etc. It can also control Sphingidae weevils, leaf beetles; Diptera subterranean flies; sooty fly and many other non-lepidopteran pests.

Uses

Chlorantraniliprole is a pyrazolylpyridine insecticide and an activator of insect ryanodine receptor. Used in Pesticide detection. (Solution)

Definition

ChEBI: Chlorantraniliprole is a carboxamide resulting from the formal condensation of the carboxylic acid group of 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylic acid with the primary amino group of 2-amino-5-chloro-N,3-dimethylbenzamide. The first of the anthranilic diamide insecticides, it is a ryanodine receptor activator and is used to protect a wide variety of crops, including corn, cotton, grapes, rice and potatoes. It has a role as a ryanodine receptor agonist. It is an organobromine compound, a member of pyridines, a member of pyrazoles, a pyrazole insecticide, a member of monochlorobenzenes and a secondary carboxamide.

Preparation

Chlorantraniliprole was synthesized by reaction of 3-bromo-1-(3-chloropyridin-2-pyridinyl)-1H-pyrazole-5carboxylic acid with 2-amino-5-chloro-3-methylbenzoic acid.3-bromo-1-(3-chloropyridin-2-pyridinyl)-1H-pyrazole5-carboxylic acid was prepared by reaction of maleic anhydride with 2,3-dichloropyridine as starting materials in eight steps.2-Amino-5-chloro-3-methylbenzoic acid was prepared by reaction of 2-amino-3-methylbenzoic acid in one step.The structure of target compound was conf irmed by 1H NMR.Total yield was 36.3%(calculated with 2,3-dichloropyridine),and purity determined by HPLC was over 95%.

Chlorantraniliprole Preparation Products And Raw materials

Raw materials

Preparation Products

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Chlorantraniliprole Suppliers

Wuhan TCASChem Technology Co., Ltd.
Tel
027-86697669 13986148687
Fax
86-027-86697669
Email
sales@tcaschem.com
Country
China
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4172
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cjbscvictory
Tel
13348960310 13348960310
Email
3003867561@qq.com
Country
China
ProdList
9945
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58
Hangzhou Taorui Biotechnology Co., Ltd
Tel
4000-360-990 15268198094
Email
sales@torreybio.com
Country
China
ProdList
2617
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58
Foshan Treasure Biotechnology Co., Ltd
Tel
0757-85921206 18520245316
Email
2329783215@qq.com
Country
China
ProdList
12664
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58
Anhui DIHE Yongxin Pharmaceutical Co., Ltd.
Tel
0556-05565590630
Email
wangqi@desano.com
Country
China
ProdList
310
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58
Shandong Yatu Biotechnology Co. LTD
Tel
0531-55555418 15301096991
Email
811301959@qq.com
Country
China
ProdList
565
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58
Hubei DAHAO Chemical Co., Ltd.
Tel
027-59106191 13986041085
Email
1400868877@qq.com
Country
China
ProdList
9987
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58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
18621169109
Email
market03@meryer.com
Country
China
ProdList
27996
Advantage
58
ATK CHEMICAL COMPANY LIMITED
Tel
+undefined-21-51877795
Fax
+86 21 5161 9052/ 5187 7796
Email
ivan@atkchemical.com
Country
China
ProdList
32480
Advantage
60
ZHEJIANG JIUZHOU CHEM CO., LTD
Tel
+86-0576225566889 +86-13454675544
Email
admin@jiuzhou-chem.com;jamie@jiuzhou-chem.com;alice@jiuzhou-chem.com
Country
China
ProdList
20000
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58

500008-45-7, ChlorantraniliproleRelated Search:


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