Description
ChemicalBook > CAS DataBase List > Chlorantraniliprole

Chlorantraniliprole

Description
Product Name
Chlorantraniliprole
CAS No.
500008-45-7
Chemical Name
Chlorantraniliprole
Synonyms
CHLOANTRANILIPROLE;Clorantraniliprole;Chlorantranilipol;Chlorantraniliprole [iso];Chlorantraniliprole 35%WDG;3-Bromo-4-chloro-1-(3-chloro-2-pyridyl)-2-methyl-6-(methylcarbamoyl)pyrazole-5-carboxanilide;3-Bromo-N-[4-chloro-2-methyl-6-[(methylamino)carbonyl]phenyl]-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxamide;Coragen;Altacor;Rynaxpyr
CBNumber
CB01404014
Molecular Formula
C18H14BrCl2N5O2
Formula Weight
483.15
MOL File
500008-45-7.mol
More
Less

Chlorantraniliprole Property

Melting point:
approximate 225℃ (dec.)
Boiling point:
526.6±50.0 °C(Predicted)
Density 
1.66±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
pka
10.19±0.70(Predicted)
CAS DataBase Reference
500008-45-7
EPA Substance Registry System
1H-Pyrazole-5-carboxamide, 3-bromo-N-[4-chloro-2-methyl-6-[(methylamino)carbonyl]phenyl]-1-(3-chloro-2-pyridinyl)- (500008-45-7)
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37
Safety Statements 
26
Hazardous Substances Data
500008-45-7(Hazardous Substances Data)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
24140
Product name
Chlorantraniliprole
Packaging
10mg
Price
$50
Updated
2023/01/06
Cayman Chemical
Product number
24140
Product name
Chlorantraniliprole
Packaging
25mg
Price
$96
Updated
2023/01/06
Cayman Chemical
Product number
24140
Product name
Chlorantraniliprole
Packaging
5mg
Price
$28
Updated
2023/01/06
Cayman Chemical
Product number
24140
Product name
Chlorantraniliprole
Packaging
50mg
Price
$163
Updated
2023/01/06
TRC
Product number
CRM0005
Product name
ChlorantraniliproleSolution(0.1mg/mLin1:1Acetonitrile/MeOH)
Packaging
1mg
Price
$165
Updated
2021/12/16
More
Less

Chlorantraniliprole Chemical Properties,Usage,Production

Description

Chlorantraniliprole (Rynaxpyr) is an insecticide of the ryanoid class. It is a new compound by DuPont belonging to a new class of selective insecticides (anthranilic diamides) featuring a novel mode of action (group 28 in the IRAC classification). It is the first anthranilic diamide registered for use on turfgrass and landscape ornamentals. It is used to control a broad spectrum of pests including cabbage loopers, corn borers, Colorado potato beetle, European grapevine moth, armyworms and cutwormson a range of crops including potatoes and cotton. Its mechanism of action is through activating the insect ryanodine receptors (RyRs), further stimulating the release and depletion of intracellular calcium stores from the sarcoplasmic reticulum of muscle cells, causing impaired muscle regulation, paralysis and ultimately death of sensitive species.

Description

Chlorantraniliprole is an anthranilic diamide insecticide and agonist of ryanodine receptors located on the sarcoplasmic reticulum in muscle and endoplasmic reticulum in non-muscle cells. It binds to a different site than ryanodine on the receptor and stimulates the release of calcium from intracellular stores with EC50 values ranging from 40 to 50 nM for P. americana neurons and H. virescens or D. melanogaster recombinant ryanodine receptors. It is highly selective for insect over mammalian ryanodine receptors (EC50s = 14,000 nM, >100 μM, and >100 μM for C2C12 mouse, PC12 rat, and IMR32 human cells, respectively). Chlorantraniliprole is active against insects of the order Lepidoptera, including larvae of the fall armyworm (S. frugiperda), diamondback moth (P. xylostella), and tobacco budworm (H. virescens) with EC50 values of 0.02, 0.01, and 0.05 ppm, respectively, and of the orders Coleoptera, Diptera, and Isoptera. Formulations containing chlorantraniliprole have been used in agriculture to control moths, beetles, and caterpillars among other insects.

Chemical Properties

White crystal, specific gravity (for liquid) 1.507g/mL, melting point 208-210℃, decomposition temperature 330℃, vapor pressure (under 20~25) 6.3×1012Pa, solubility (under 20~25, mg/L): water 1.023, acetone 3.446, methanol 1.714, acetonitrile 0.711, ethyl acetate 1.144. Chlorfenvinphos It is highly efficient and broad-spectrum, and has good control effect on Lepidoptera of Noctuidae, stem borer moths, fruit moths, leaf roller moths, pink moths, vegetable moths, wheat moths, and fine moths, etc. It can also control Sphingidae weevils, leaf beetles; Diptera subterranean flies; sooty fly and many other non-lepidopteran pests.

Uses

Chlorantraniliprole is a pyrazolylpyridine insecticide and an activator of insect ryanodine receptor.

Uses

Chlorantraniliprole is a pyrazolylpyridine insecticide and an activator of insect ryanodine receptor. Used in Pesticide detection. (Solution)

Definition

ChEBI: Chlorantraniliprole is a carboxamide resulting from the formal condensation of the carboxylic acid group of 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylic acid with the primary amino group of 2-amino-5-chloro-N,3-dimethylbenzamide. The first of the anthranilic diamide insecticides, it is a ryanodine receptor activator and is used to protect a wide variety of crops, including corn, cotton, grapes, rice and potatoes. It has a role as a ryanodine receptor agonist. It is an organobromine compound, a member of pyridines, a member of pyrazoles, a pyrazole insecticide, a member of monochlorobenzenes and a secondary carboxamide.

Preparation

Chlorantraniliprole was synthesized by reaction of 3-bromo-1-(3-chloropyridin-2-pyridinyl)-1H-pyrazole-5carboxylic acid with 2-amino-5-chloro-3-methylbenzoic acid.3-bromo-1-(3-chloropyridin-2-pyridinyl)-1H-pyrazole5-carboxylic acid was prepared by reaction of maleic anhydride with 2,3-dichloropyridine as starting materials in eight steps.2-Amino-5-chloro-3-methylbenzoic acid was prepared by reaction of 2-amino-3-methylbenzoic acid in one step.The structure of target compound was conf irmed by 1H NMR.Total yield was 36.3%(calculated with 2,3-dichloropyridine),and purity determined by HPLC was over 95%.

Chlorantraniliprole Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Chlorantraniliprole Suppliers

Wuhan TCASChem Technology Co., Ltd.
Tel
027-86697669 13986148687
Email
947257336@qq.com
Country
China
ProdList
3921
Advantage
55
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15935
Advantage
55
U-Chemo Scientific(Shanghai) Co.,Ltd
Tel
021-58380326 13585932672
Email
3251669772@qq.com
Country
China
ProdList
980
Advantage
58
cjbscvictory
Tel
13348961525
Email
3003867561@qq.com
Country
China
ProdList
10005
Advantage
58
Hangzhou Taorui Biotechnology Co., Ltd
Tel
--
Fax
--
Email
sales@torreybio.com
Country
China
ProdList
1539
Advantage
58
Foshan Treasure Biotechnology Co., Ltd
Tel
0757-85921206 18520245316
Email
2329783215@qq.com
Country
China
ProdList
12664
Advantage
58
Anhui DIHE Yongxin Pharmaceutical Co., Ltd.
Tel
05565590630 18915922978
Email
dingjianqing@desano.com
Country
China
ProdList
313
Advantage
58
Shandong Yatu Biotechnology Co. LTD
Tel
0531-55555418 15301096991
Email
811301959@qq.com
Country
China
ProdList
522
Advantage
58
Hubei DAHAO Chemical Co., Ltd.
Tel
13986034860
Email
1400878877@qq.com
Country
China
ProdList
9721
Advantage
58
Hubei Tuobang Chemical Co., Ltd.
Tel
13986192185
Email
1158480077@qq.com
Country
China
ProdList
10166
Advantage
58

500008-45-7, ChlorantraniliproleRelated Search:


  • CHLOANTRANILIPROLE
  • CHLORANTRANILIPROLE
  • 3-Bromo-4-chloro-1-(3-chloro-2-pyridyl)-2-methyl-6-(methylcarbamoyl)pyrazole-5-carboxanilide
  • Chlorantraniliprole [iso]
  • Rynaxpyr
  • Chlorantranilipol
  • 3-Bromo-N-[4-chloro-2-methyl-6-[(methylamino)carbonyl]phenyl]-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxamide
  • DPX E2Y45
  • Chlorantraniliprole Standard
  • Clorantraniliprole
  • Chlorantraniliprole 95%
  • Coragen
  • Chlorantraniliprole 95% (Rynaxypyr, Coragen)
  • Chlorantraniliprole Solution, 1000ppm
  • 1H-Pyrazole-5-carboxamide,3-bromo-N-[4-chloro-2-methyl-6-[(methylamino)carbonyl]phenyl]-1-(3-chloro-2-pyridinyl)-
  • 5-bromo-N-[2-chloro-4-methyl-6-(methylcarbamoyl)phenyl]-2-(3-chloro-2-pyridinyl)-3-pyrazolecarboxamide
  • 5-bromo-N-[4-chloro-2-methyl-6-(methylcarbamoyl)phenyl]-2-(3-chloropyridin-2-yl)pyrazole-3-carboxamide
  • Chlorantraniliprole@100 μg/mL in Methanol
  • Chlorantraniliprole@1000 μg/mL in Methanol
  • [Carbonyl-14C1]14C-chlorantraniliprole
  • Chlorantraniliprole Solution
  • Chlorantraniliprole Solution in Methanol, 100μg/mL
  • Altacor
  • Clorantraniliprole 35% WDG
  • Chlorantraniliprole Solution (0.1 mg/mL in 1:1 Acetonitrile/MeOH)
  • Chlorantraniliprole 95%TC & 35%WG
  • Chlorantraniliprole 95%TC
  • Chlorantraniliprole 35%WDG
  • Altacor (Chlorantraniliprole 35% WG)
  • 500008-45-7
  • C18H14BrCl2N5O2
  • pesticide
  • Agro-Products