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Thiamethoxam

Product Name
Thiamethoxam
CAS No.
153719-23-4
Chemical Name
Thiamethoxam
Synonyms
Thiametoxam;Actara;hiamethoxam;Thiomethoxam;3-(2-CHLORO-5-THIAZOLYLMETHYL)TETRAHYDRO-5-METHYL-N-NITRO-4H-1,3,5-OXADIAZIN-4-IMINE;Adage;Cruiser;Adage 5fs;Actara(TM);Actara 2gr
CBNumber
CB5105069
Molecular Formula
C8H10ClN5O3S
Formula Weight
291.71
MOL File
153719-23-4.mol
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Thiamethoxam Property

Melting point:
139.1°
Boiling point:
485.8±55.0 °C(Predicted)
Density 
1.71±0.1 g/cm3(Predicted)
vapor pressure 
6.6 x 10-9 Pa (25 °C)
storage temp. 
Inert atmosphere,2-8°C
solubility 
DMSO: 250 mg/mL (857.02 mM)
Water Solubility 
4.1 x 103 mg l-1 (25 °C)
form 
Solid
pka
0.99±0.10(Predicted)
color 
Off-white to yellow
BRN 
8491021
InChI
InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3
InChIKey
NWWZPOKUUAIXIW-DHZHZOJOSA-N
SMILES
O1CN(C)C(=N[N+]([O-])=O)N(CC2SC(Cl)=NC=2)C1
LogP
-0.13 at 25℃
EPA Substance Registry System
Thiamethoxam (153719-23-4)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-50/53
Safety Statements 
22-61-60
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
2
HS Code 
29341000
Hazardous Substances Data
153719-23-4(Hazardous Substances Data)
Toxicity
LD50 in rats (mg/kg): 1563 orally, >2000 dermally; LD50 in bobwhite quail, mallard duck (mg/kg): 1552, 576 orally. LC50 (96hr) in rainbow trout, bluegill (mg/l): >100, >114 (Senn).
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
37924
Product name
Thiamethoxam
Purity
PESTANAL?, analytical standard
Packaging
100mg
Price
$90.1
Updated
2024/03/01
Cayman Chemical
Product number
25784
Product name
Thiamethoxam
Purity
≥98%
Packaging
100mg
Price
$74
Updated
2024/03/01
Cayman Chemical
Product number
25784
Product name
Thiamethoxam
Packaging
50mg
Price
$44
Updated
2024/03/01
TRC
Product number
T344180
Product name
Thiamethoxam
Packaging
2g
Price
$175
Updated
2021/12/16
ApexBio Technology
Product number
C6737
Product name
Thiamethoxam
Packaging
1g
Price
$180
Updated
2021/12/16
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Thiamethoxam Chemical Properties,Usage,Production

Chemical Properties

Off-White to Pale Yellow Solid

Uses

Thiamethoxam is a broad spectrum insecticide active against a wide spectrum of sucking and chewing insect pests after foliar, soil or seed treatment.

Definition

ChEBI: Thiamethoxam is an oxadiazane that is tetrahydro-N-nitro-4H-1,3,5-oxadiazin-4-imine bearing (2-chloro-1,3-thiazol-5-yl)methyl and methyl substituents at positions 3 and 5 respectively. It has a role as an antifeedant, a carcinogenic agent, an environmental contaminant, a xenobiotic and a neonicotinoid insectide. It is an oxadiazane, a member of 1,3-thiazoles, an organochlorine compound and a 2-nitroguanidine derivative. It derives from a 2-chlorothiazole.

Application

Thiamethoxam is a neonicotinoid insecticide that is used widely in Wisconsin. Thiamethoxam is the active ingredient in a variety of products used in agriculture to kill sucking and chewing insects that feed on roots, leaves, and other plant tissues. Agricultural uses include soil and seed treatments as well as leaf spraying for most row and vegetable crops like corn, soybeans, snap beans, and potatoes. It is also used to control insects in livestock pens, poultry houses, sod farms, golf courses, lawns, household plants, and tree nurseries. It was first registered by the U.S. Environmental Protection Agency in 1999. Reports show that when exposed to neonicotinid pesticides honeybees have probelms returnign home after foraging and bumblebee colonies grow poorly and produce fewer queens.

Flammability and Explosibility

Flammable

Metabolic pathway

All the information on thiamethoxam is taken from a summary of the proceedings of meeting published by the manufacturer. Full experimental details are not given in the report and the identity of metabolites is not disclosed (Novartis, 1997).

Degradation

Thiamethoxam is hydrolytically stable at pH 5 (half-life about 200-300 days). The compound is more labile at pH 9 where the half-life is a few days. It is rapidly photodegraded with a half-life of about 1 hour. In aquatic systems, degradation occurs under alkaline conditions and the insecticide is rapidly photodegraded but not readily biodegraded (Novartis, 1997).

Mode of action

Thiamethoxam interferes with nicotinic acetylcholine receptors in the insect’s nervous system, which are essential for proper functioning of the nerves. Within hours of contact or ingestion of thiamethoxam, insects stop feeding. Death usually occurs within 24 to 48 hours.
The activity of thiamethoxam, or any insecticide, at the target site is just one factor in its efficacy. When comparing insecticides, other variables – including how the compound interacts with the environment, the plant and the insect – also contribute to its insecticidal mode of action.
The Insecticide Resistance Action Committee (IRAC) has organized insecticides into 28 groups, plus sub-groups, based on their modes of action. Thiamethoxam is a Group 4A insecticide (neonicotinoids).

Thiamethoxam Preparation Products And Raw materials

Raw materials

Preparation Products

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Thiamethoxam Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Rudong Zhongyi Chemical Co., Ltd
Tel
13306234115
Fax
+86-0513-84819568
Email
jszyzj@zhongyichem.com
Country
China
ProdList
36
Advantage
60
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
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View Lastest Price from Thiamethoxam manufacturers

HebeiShuoshengImportandExportco.,Ltd
Product
Thiamethoxam 153719-23-4
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-05
Hebei Weibang Biotechnology Co., Ltd
Product
Thiamethoxam 153719-23-4
Price
US $19.00/KG
Min. Order
100KG
Purity
99%
Supply Ability
100 mt
Release date
2024-11-20
Hebei Longbang Technology Co., Ltd
Product
Thiamethoxam 153719-23-4
Price
US $6.00/kg
Min. Order
1kg
Purity
More than 99%
Supply Ability
2000KG/Month
Release date
2024-05-27

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