ChemicalBook > CAS DataBase List > Thiamethoxam

Thiamethoxam

Product Name
Thiamethoxam
CAS No.
153719-23-4
Chemical Name
Thiamethoxam
Synonyms
Thiametoxam;Actara;hiamethoxam;Thiomethoxam;3-(2-CHLORO-5-THIAZOLYLMETHYL)TETRAHYDRO-5-METHYL-N-NITRO-4H-1,3,5-OXADIAZIN-4-IMINE;Adage;Cruiser;Adage 5fs;Actara(TM);Actara 2gr
CBNumber
CB5105069
Molecular Formula
C8H10ClN5O3S
Formula Weight
291.71
MOL File
153719-23-4.mol
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Thiamethoxam Property

Melting point:
139.1°
Boiling point:
485.8±55.0 °C(Predicted)
Density 
1.71±0.1 g/cm3(Predicted)
vapor pressure 
6.6 x 10-9 Pa (25 °C)
storage temp. 
Inert atmosphere,2-8°C
solubility 
DMSO: 250 mg/mL (857.02 mM)
Water Solubility 
4.1 x 103 mg l-1 (25 °C)
form 
Solid
pka
0.99±0.10(Predicted)
color 
Off-white to yellow
BRN 
8491021
InChI
InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3
InChIKey
NWWZPOKUUAIXIW-DHZHZOJOSA-N
SMILES
O1CN(C)C(=N[N+]([O-])=O)N(CC2SC(Cl)=NC=2)C1
LogP
-0.13 at 25℃
EPA Substance Registry System
Thiamethoxam (153719-23-4)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-50/53
Safety Statements 
22-61-60
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
2
HS Code 
29341000
Hazardous Substances Data
153719-23-4(Hazardous Substances Data)
Toxicity
LD50 in rats (mg/kg): 1563 orally, >2000 dermally; LD50 in bobwhite quail, mallard duck (mg/kg): 1552, 576 orally. LC50 (96hr) in rainbow trout, bluegill (mg/l): >100, >114 (Senn).
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
37924
Product name
Thiamethoxam
Purity
PESTANAL?, analytical standard
Packaging
100mg
Price
$90.1
Updated
2024/03/01
Cayman Chemical
Product number
25784
Product name
Thiamethoxam
Purity
≥98%
Packaging
100mg
Price
$74
Updated
2024/03/01
Cayman Chemical
Product number
25784
Product name
Thiamethoxam
Packaging
50mg
Price
$44
Updated
2024/03/01
TRC
Product number
T344180
Product name
Thiamethoxam
Packaging
2g
Price
$175
Updated
2021/12/16
ApexBio Technology
Product number
C6737
Product name
Thiamethoxam
Packaging
1g
Price
$180
Updated
2021/12/16
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Thiamethoxam Chemical Properties,Usage,Production

Chemical Properties

Off-White to Pale Yellow Solid

Uses

Thiamethoxam is a broad spectrum insecticide active against a wide spectrum of sucking and chewing insect pests after foliar, soil or seed treatment.

Definition

ChEBI: Thiamethoxam is an oxadiazane that is tetrahydro-N-nitro-4H-1,3,5-oxadiazin-4-imine bearing (2-chloro-1,3-thiazol-5-yl)methyl and methyl substituents at positions 3 and 5 respectively. It has a role as an antifeedant, a carcinogenic agent, an environmental contaminant, a xenobiotic and a neonicotinoid insectide. It is an oxadiazane, a member of 1,3-thiazoles, an organochlorine compound and a 2-nitroguanidine derivative. It derives from a 2-chlorothiazole.

Application

Thiamethoxam is a neonicotinoid insecticide that is used widely in Wisconsin. Thiamethoxam is the active ingredient in a variety of products used in agriculture to kill sucking and chewing insects that feed on roots, leaves, and other plant tissues. Agricultural uses include soil and seed treatments as well as leaf spraying for most row and vegetable crops like corn, soybeans, snap beans, and potatoes. It is also used to control insects in livestock pens, poultry houses, sod farms, golf courses, lawns, household plants, and tree nurseries. It was first registered by the U.S. Environmental Protection Agency in 1999. Reports show that when exposed to neonicotinid pesticides honeybees have probelms returnign home after foraging and bumblebee colonies grow poorly and produce fewer queens.

Flammability and Explosibility

Flammable

Metabolic pathway

All the information on thiamethoxam is taken from a summary of the proceedings of meeting published by the manufacturer. Full experimental details are not given in the report and the identity of metabolites is not disclosed (Novartis, 1997).

Degradation

Thiamethoxam is hydrolytically stable at pH 5 (half-life about 200-300 days). The compound is more labile at pH 9 where the half-life is a few days. It is rapidly photodegraded with a half-life of about 1 hour. In aquatic systems, degradation occurs under alkaline conditions and the insecticide is rapidly photodegraded but not readily biodegraded (Novartis, 1997).

Mode of action

Thiamethoxam interferes with nicotinic acetylcholine receptors in the insect’s nervous system, which are essential for proper functioning of the nerves. Within hours of contact or ingestion of thiamethoxam, insects stop feeding. Death usually occurs within 24 to 48 hours.
The activity of thiamethoxam, or any insecticide, at the target site is just one factor in its efficacy. When comparing insecticides, other variables – including how the compound interacts with the environment, the plant and the insect – also contribute to its insecticidal mode of action.
The Insecticide Resistance Action Committee (IRAC) has organized insecticides into 28 groups, plus sub-groups, based on their modes of action. Thiamethoxam is a Group 4A insecticide (neonicotinoids).

Thiamethoxam Preparation Products And Raw materials

Raw materials

Preparation Products

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Thiamethoxam Suppliers

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View Lastest Price from Thiamethoxam manufacturers

HebeiShuoshengImportandExportco.,Ltd
Product
Thiamethoxam 153719-23-4
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-05
Hebei Weibang Biotechnology Co., Ltd
Product
Thiamethoxam 153719-23-4
Price
US $19.00/KG
Min. Order
100KG
Purity
99%
Supply Ability
100 mt
Release date
2024-11-20
Hebei Longbang Technology Co., Ltd
Product
Thiamethoxam 153719-23-4
Price
US $6.00/kg
Min. Order
1kg
Purity
More than 99%
Supply Ability
2000KG/Month
Release date
2024-05-27

153719-23-4, ThiamethoxamRelated Search:


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