ChemicalBook > CAS DataBase List > 3-ACETAMIDOPHENOL

3-ACETAMIDOPHENOL

Product Name
3-ACETAMIDOPHENOL
CAS No.
621-42-1
Chemical Name
3-ACETAMIDOPHENOL
Synonyms
Nebs;bs479;Rystal;BS 479;BS 749;Pyrapap;Metalid;NSC 3990;Pedituss;metacetamol
CBNumber
CB0108898
Molecular Formula
C8H9NO2
Formula Weight
151.16
MOL File
621-42-1.mol
More
Less

3-ACETAMIDOPHENOL Property

Melting point:
145-148 °C(lit.)
Boiling point:
273.17°C (rough estimate)
Density 
1.249
refractive index 
1.5810 (estimate)
storage temp. 
2-8°C
form 
Crystals, Crystalline Powder or Needles
color 
Off-white to tan or light gray
PH
6-7 (H2O)(saturated solution)
BRN 
907998
CAS DataBase Reference
621-42-1(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38
Safety Statements 
26-36
RIDADR 
2811
WGK Germany 
2
RTECS 
AE4100000
1-8
Hazard Note 
Irritant
TSCA 
Yes
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29242995
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A7205
Product name
3-Acetamidophenol
Purity
97%
Packaging
25g
Price
$31.4
Updated
2018/11/13
Sigma-Aldrich
Product number
19374
Product name
3-Acetamidophenol
Purity
analytical standard
Packaging
100mg
Price
$77.2
Updated
2018/11/13
TCI Chemical
Product number
H0188
Product name
3'-Hydroxyacetanilide
Purity
>98.0%(T)
Packaging
25g
Price
$33
Updated
2018/11/22
TCI Chemical
Product number
H0188
Product name
3'-Hydroxyacetanilide
Purity
>98.0%(T)
Packaging
500g
Price
$218
Updated
2018/11/22
Alfa Aesar
Product number
A12764
Product name
3-Acetamidophenol, 99%
Packaging
25g
Price
$22.7
Updated
2018/11/13
More
Less

3-ACETAMIDOPHENOL Chemical Properties,Usage,Production

Chemical Properties

off-white to tan or light grey crystals,

Uses

analgesic

Definition

ChEBI: A derivative of phenol which has an acetamido substituent located meta to the phenolic -OH group. It is a non-toxic regioisomer of paracetamol with analgesic properties, but has never been marketed as a drug.

General Description

Light gray solid.

Air & Water Reactions

Water insoluble.

Reactivity Profile

Phenols do not behave as organic alcohols, as one might guess from the presence of a hydroxyl (-OH) group in their structure. Instead, they react as weak organic acids. Phenols and cresols are much weaker as acids than common carboxylic acids (phenol has Ka = 1.3 x 10^[-10]). These materials are incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction between phenols and bases. Phenols are sulfonated very readily (for example, by concentrated sulfuric acid at room temperature). The reactions generate heat. Phenols are also nitrated very rapidly, even by dilute nitric acid. Nitrated phenols often explode when heated. Many of them form metal salts that tend toward detonation by rather mild shock. Flammable gases are formed by the reaction of organic amides with strong reducing agents. Amides are very weak bases (weaker than water). Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

Fire Hazard

Flash point data for 3-ACETAMIDOPHENOL are not available. 3-ACETAMIDOPHENOL is probably combustible.

Purification Methods

Recrystallise the phenol from water. The 3,5-dinitrobenzamide complex gives orange-yellow crystals from hot H2O and has m 212o. [Beilstein 13 H 415, 13 I 132, 13 II 213, 13 III 950, 13 IV 977.]

3-ACETAMIDOPHENOL Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

3-ACETAMIDOPHENOL Suppliers

J & K SCIENTIFIC LTD.
Tel
400-666-7788 +86-10-82848833
Fax
86-10-82849933
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
+86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
Fax
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing)
Email
sh@meryer.com
Country
China
ProdList
40269
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
86-21-50328103 * 801、802、803、804 Mobile:18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15881
Advantage
69
Alfa Aesar
Tel
400-610-6006; 021-67582000
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30163
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386 / 800-988-0390
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24555
Advantage
81
Energy Chemical
Tel
021-58432009 / 400-005-6266
Fax
021-58436166-800
Email
info@energy-chemical.com
Country
China
ProdList
44025
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18228
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
+86-10-4006331231;+86-10-51280831;+86-10-82967028
Fax
+86-10-82967029
Email
sales@ouhechem.com
Country
China
ProdList
12495
Advantage
60
BePharm Ltd
Tel
4001-647-117; 021-61629020
Fax
021-61629029
Email
product@bidepharmatech.com
Country
China
ProdList
24689
Advantage
61
Syntechem Co.,Ltd
Tel
Please Email
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
13010
Advantage
57

621-42-1, 3-ACETAMIDOPHENOLRelated Search:


  • Pyrapap
  • Rystal
  • M-ACETAMIDOPHENOL
  • M-ACETAMINOPHENOL
  • ACETAMIDOPHENOL-3
  • 3-ACETAMIDOPHENOL
  • 3-ACETAMINOPHENOL
  • 3'-HYDROXYACETANILIDE
  • 3-HYDROXYACETANILIDE
  • 3-Acetamidophenol;N-Acetyl-m-aminophenol;m-Hydroxyacetanilide;3-Hydroxyacetanilide
  • 3-ACETAMIDOPHENOL 99+%
  • META-HYDROXYACETANILIDE
  • N-ACETYL-META-AMINOPHENOL
  • m-Hydroxyacetanilide N-(3-Hydroxyphenyl)acetamide
  • N-(3-Hydroxyphenyl)acetamide, tech
  • 3-AcetaMidophenol, 99+% 25GR
  • N-Acetyl-3-hydroxyaniline
  • NSC 3990
  • 3'-Hydroxyacetanilide , 98.0%(T)
  • 3-Acetamidophenol 97%
  • Bosutinib Impurity 10
  • N-(3-HYDROXYPHENYL)ACETAMIDE
  • M-HYDROXYACETANILIDE
  • 3-(Acetylamino)-1-hydroxybenzene
  • 3-(Acetylamino)phenol
  • 3’-hydroxy-acetanilid
  • 3-Hydroxy-4-trimethylammoniobutanoate3'-hydroxyacetanilide
  • Acetamide, N-(3-hydroxyphenyl)-
  • Acetanilide, 3'-hydroxy-
  • BS 479
  • BS 749
  • bs479
  • m-(Acetylamino)phenol
  • metacetamol
  • Metalid
  • n-(3-hydroxyphenyl)-acetamid
  • N-Acetyl-m-Aminophenol
  • Nebs
  • Pedituss
  • Neratinib-001
  • 621-42-1
  • Building Blocks
  • Phenols
  • Oxygen Compounds
  • Organic Building Blocks
  • Aromatic Phenols
  • Phenol&Thiophenol&Mercaptan
  • Anilines, Amides & Amines
  • Phenols