Cefminox

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Product Name: Cefminox
CAS No.: 75481-73-1
Chemical Name: Cefminox
Synonyms: Meicelin;CEFMINOX;CEFMINOX SOUDIUM;Cefminox USP/EP/BP;Cefminox sodium salt;7-[[2-[(2-amino-2-carboxyethyl)thio]-1-oxoethyl]amino]-7-methoxy-3-[[(1-methyl-5-tetrazolyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;(6r,7s)-7-(2-(((s)-2-amino-2-carboxyethyl)thio)acetamido)-7-methoxy-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid;(6R,7S)-7-[[2-[[(2S)-2-amino-3-hydroxy-3-keto-propyl]thio]acetyl]amino]-8-keto-7-methoxy-3-[[(1-methyltetrazol-5-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;(6R,7S)-7-[[2-[(2S)-2-amino-3-hydroxy-3-oxopropyl]sulfanylacetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[[(2S)-2-amino-2-carboxyethyl]thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, sodium salt, (6R,7S)-
CBNumber: CB0109082
Molecular Formula: C16H21N7O7S3
Formula Weight: 519.58
MOL File: 75481-73-1.mol

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Cefminox Property

CAS DataBase Reference: 75481-73-1(CAS DataBase Reference)

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Hazard and Precautionary Statements (GHS)

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Cefminox Chemical Properties,Usage,Production

Definition

ChEBI: Cefminox is a second-generation cephamycin antibiotic having [(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl and 2-{[(2S)-2-amino-2-carboxyethyl]sulfanyl}acetamido side-groups located respectively at positions 3 and 7beta of the cephem nucleus. A broad-spectrum bactericide, it is especially effective against Gram-negative and anaerobic bacteria. It is a cephamycin and a member of tetrazoles. It is a conjugate acid of a cefminox(1-).

Antimicrobial activity

A semisynthetic cephamycin. Activity is similar to that of cefoxitin and cefotetan, but the activity against enterobacteria and B. fragilis is somewhat better . C. difficile is inhibited by 4–16 mg/L. It is stable to the common β-lactamases of enterobacteria and Bacteroides spp.
A 15-min intravenous infusion of 1 g achieves a serum concentration of 30 mg/L after 1 h. The plasma half-life is c. 2 h and around 68% is protein bound.
Its safety profile and uses are similar to those of other cephamycins. It is available in Japan.

Cefminox Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Cefminox manufacturers

Shaanxi TNJONE Pharmaceutical Co., Ltd

Product: Cefminox 75481-73-1
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-05-16

Zhuozhou Wenxi import and Export Co., Ltd

Product: Cefminox 75481-73-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-10

Hebei Henghe Import and Export Trading Co. LTD

Product: Cefminox 75481-73-1
Price: US $230.00/KG
Min. Order: 100KG
Purity: 99%
Supply Ability: 10
Release date: 2020-12-09

75481-73-1, CefminoxRelated Search:

Glycine 2-Methoxyethanol ALTRENOGEST Acetaminophen Ceftriaxone sodium Oxygen 7-TMCA (6R-(6-alpha,7-alpha))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt 1-METHYL-3-AZETIDINOL 3-METHOXY-AZETIDINE ACETAMINOPHENOL BP/USP AMINO ACIDS Cefminox 1H-Tetrazole, 5-((3-(ethylthio)propyl)thio)-1-methyl- Methoxy CEFMINOXSODIUM

(6r-(6-alpha,7-alpha))-7-((((2-amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt

(6r,7s)-7-(2-(((s)-2-amino-2-carboxyethyl)thio)acetamido)-7-methoxy-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid

CEFMINOX SOUDIUM

7-[[2-[(2-amino-2-carboxyethyl)thio]-1-oxoethyl]amino]-7-methoxy-3-[[(1-methyl-5-tetrazolyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(2-amino-2-carboxyethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, sodium salt, [6R-[6α,7α,7(S*)]]-

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[[(2S)-2-amino-2-carboxyethyl]thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, sodium salt, (6R,7S)-

Cefminox sodium salt

Meicelin

(6R,7S)-7-[[2-[(2S)-2-amino-3-hydroxy-3-oxopropyl]sulfanylacetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7S)-7-[[2-[[(2S)-2-amino-3-hydroxy-3-keto-propyl]thio]acetyl]amino]-8-keto-7-methoxy-3-[[(1-methyltetrazol-5-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7S)-7-[2-[(2S)-2-azanyl-3-hydroxy-3-oxo-propyl]sulfanylethanoylamino]-7-methoxy-3-[(1-methyl-1,2,3,4-tetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

CEFMINOX

Cefminox USP/EP/BP

75481-73-1

C16H20N7O7S3Na

C16H21N7O7S3

C16H20N7NaO7S3