(6R-(6-alpha,7-alpha))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt

Product Name: (6R-(6-alpha,7-alpha))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt
CAS No.: 75498-96-3
Chemical Name: (6R-(6-alpha,7-alpha))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt
Synonyms: Cefminol sodium;Cefminox impurity;CefMinox、 Meicilin;Meicelin Heptahydrate;Cefminox Sodium Hydrate;Cefminox sodium (MT-141);Cefminox Sodium(Sterile);CefMinox SodiuM Heptahydrate;CefMinox SodiuM Salt Heptahydrate;(6r-(6-alpha,7-alpha))-7-((((2-amino-2-carboxyethyl)thio)ace...
CBNumber: CB22130365
Molecular Formula: C16H20N7NaO7S3
Formula Weight: 541.56
MOL File: 75498-96-3.mol

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(6R-(6-alpha,7-alpha))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt Property

Melting point:: 90-91 °C
storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form: Solid
color: White to Pale Yellow
Water Solubility: Water: 83.33 mg/mL (153.87 mM)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: C243100
Product name: CefminoxSodiumHeptahydrate
Packaging: 500mg
Price: $185
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0001893
Product name: CEFMINOX SODIUM
Purity: 95.00%
Packaging: 5MG
Price: $550
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0001893
Product name: CEFMINOX SODIUM
Purity: 95.00%
Packaging: 500MG
Price: $750.75
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0001893
Product name: CEFMINOX SODIUM
Purity: 95.00%
Packaging: 5G
Price: $2136.75
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 63542
Product name: CefminoxSodiumHeptahydrate
Packaging: 5G
Price: $2200
Updated: 2021/12/16

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(6R-(6-alpha,7-alpha))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Cefminox is a semisynthetic broad spectrum cephamycin antibiotic. Antibacterial.

Definition

ChEBI: Cefminox sodium is an organic sodium salt of cefminox. It contains a cefminox(1-).

Synthesis

52-89-1

57617-09-1

75498-96-3

Synthesis of (6R,7S)-7-(2-((S)-2-amino-2-carboxyethyl)thio)acetamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0 The general procedure for the sodium salt of ]oct-2-ene-2-carboxylic acid was as follows: 433.1 g of 7β-chloroacetamido-7a-methoxy-3-(1-methyl-1H-tetrazol-5-ylthiomethyl)-3-cephalosporan-4-carboxylic acid was added to 2 L of water, followed by the addition of 30 g of EDTA and 412 g of sodium thiosulfate. The reaction mixture was stirred at 50 °C and the progress of the reaction was monitored by thin layer chromatography (TLC). After completion of the reaction, the mixture was cooled to room temperature and a mixed solution consisting of 1500 mL of ethanol and 500 mL of acetone was added. The resulting precipitate was filtered and dried to give 530 g of cefminox sodium in 97.9% yield. The product was analyzed by high performance liquid chromatography (HPLC) and the purity was 99.5%.

IC 50

PPARγ; IP Receptor; Bacterial

References

[1] Patent: CN105924456, 2016, A. Location in patent: Paragraph 0033; 0035

(6R-(6-alpha,7-alpha))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

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(6R-(6-alpha,7-alpha))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt Suppliers

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View Lastest Price from (6R-(6-alpha,7-alpha))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: (6R-(6-alpha,7-alpha))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)... 75498-96-3
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-10-18

Career Henan Chemical Co

Product: Cefminox sodium 75498-96-3
Price: US $3.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2019-08-07

75498-96-3, (6R-(6-alpha,7-alpha))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium saltRelated Search:

Sodium acetate Carbenicillin disodium Sodium hydroxide Sodium gluconate ALTRENOGEST Cephalexin Sodium carboxymethyl cellulose Acetylacetone Sodium benzoate Glycine Sodium chloride Acetyl chloride Sodium carbonate Sodium carboxyl methylstarch Sodium bicarbonate Cefminox p-(2-Methoxyethyl) phenol Oxygen

CefMinox、 Meicilin

(6R,7S)-7-[[2-[[(2S)-2-Amino-2-carboxyethyl]thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid monosodium salt

(6R-(6-,7-))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt

(6R-(6-alpha,7-alpha))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt

(6R,7S)-7-[[[[(S)-2-Amino-2-carboxyethyl]thio]acetyl]amino]-7β-methoxy-3-[[(1-methyl-1H-tetrazole-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]octa-2-ene-2-carboxylic acid/sodium,(1:x) salt

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[2-[[(2S)-2-aMino-2-carboxyethyl]thio]acetyl]aMino]-7-Methoxy-3-[[(1-Methyl-1H-tetrazol-5-yl)thio]Methyl]-8-oxo-,sodiuM salt (1:1), (6R,7S)-

(6R,7S)-7-[[2-[[(2S)-2-AMino-2-carboxyethyl]thio]acetyl]aMino]-7-Methoxy-3-[[(1-Methyl-1H-tetrazol-5-yl)thio]Methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid SodiuM Salt Heptahydrate

CefMinox SodiuM Heptahydrate

CefMinox SodiuM Salt Heptahydrate

Meicelin Heptahydrate

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[2-[[(2S)-2-amino-2-carboxyethyl]thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)t

Cefminox Sodium Hydrate

sodium (6R,7S)-7-[[2-[(2-amino-2-carboxyethyl)thio]-1-oxoethyl]amino]-7-methoxy-3-[[(1-methyl-5-tetrazolyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Cefminox sodium (MT-141)

sodium (6R,7S)-7-(2-(((S)-2-amino-2-carboxyethyl)thio)acetamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylate

(6R-(6-alpha,7-alpha))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylicacidmonosodiumsal

Cefminox impurity

Sodium (6R,7S)-7-(2-(((S)-2-amino-2-carboxyethyl)thio)acetamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

(6r-(6-alpha,7-alpha))-7-((((2-amino-2-carboxyethyl)thio)ace...

Cefminol sodium

(6R-(6-alpha,7-alpha))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)...

(6R-(6-α,7-α))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylicacidmonosodiumsal

Cefminox Sodium(Sterile)

75498-96-3

C16H19N7NaO7S3

C16H34N7NaO14S3

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