(6R-(6-alpha,7-alpha))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt
- Product Name
- (6R-(6-alpha,7-alpha))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt
- CAS No.
- 75498-96-3
- Chemical Name
- (6R-(6-alpha,7-alpha))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt
- Synonyms
- Cefminol sodium;Cefminox impurity;CefMinox、 Meicilin;Meicelin Heptahydrate;Cefminox Sodium Hydrate;Cefminox sodium (MT-141);Cefminox Sodium(Sterile);CefMinox SodiuM Heptahydrate;CefMinox SodiuM Salt Heptahydrate;(6r-(6-alpha,7-alpha))-7-((((2-amino-2-carboxyethyl)thio)ace...
- CBNumber
- CB22130365
- Molecular Formula
- C16H20N7NaO7S3
- Formula Weight
- 541.56
- MOL File
- 75498-96-3.mol
(6R-(6-alpha,7-alpha))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt Property
- Melting point:
- 90-91 °C
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- solubility
- DMSO (Slightly), Methanol (Slightly), Water (Slightly)
- form
- Solid
- color
- White to Pale Yellow
- Water Solubility
- Water: 83.33 mg/mL (153.87 mM)
N-Bromosuccinimide Price
- Product number
- C243100
- Product name
- CefminoxSodiumHeptahydrate
- Packaging
- 500mg
- Price
- $185
- Updated
- 2021/12/16
- Product number
- API0001893
- Product name
- CEFMINOX SODIUM
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $550
- Updated
- 2021/12/16
- Product number
- API0001893
- Product name
- CEFMINOX SODIUM
- Purity
- 95.00%
- Packaging
- 500MG
- Price
- $750.75
- Updated
- 2021/12/16
- Product number
- API0001893
- Product name
- CEFMINOX SODIUM
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $2136.75
- Updated
- 2021/12/16
- Product number
- 63542
- Product name
- CefminoxSodiumHeptahydrate
- Packaging
- 5G
- Price
- $2200
- Updated
- 2021/12/16
(6R-(6-alpha,7-alpha))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
Cefminox is a semisynthetic broad spectrum cephamycin antibiotic. Antibacterial.
Definition
ChEBI: Cefminox sodium is an organic sodium salt of cefminox. It contains a cefminox(1-).
Synthesis
52-89-1
57617-09-1
75498-96-3
Synthesis of (6R,7S)-7-(2-((S)-2-amino-2-carboxyethyl)thio)acetamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0 The general procedure for the sodium salt of ]oct-2-ene-2-carboxylic acid was as follows: 433.1 g of 7β-chloroacetamido-7a-methoxy-3-(1-methyl-1H-tetrazol-5-ylthiomethyl)-3-cephalosporan-4-carboxylic acid was added to 2 L of water, followed by the addition of 30 g of EDTA and 412 g of sodium thiosulfate. The reaction mixture was stirred at 50 °C and the progress of the reaction was monitored by thin layer chromatography (TLC). After completion of the reaction, the mixture was cooled to room temperature and a mixed solution consisting of 1500 mL of ethanol and 500 mL of acetone was added. The resulting precipitate was filtered and dried to give 530 g of cefminox sodium in 97.9% yield. The product was analyzed by high performance liquid chromatography (HPLC) and the purity was 99.5%.
IC 50
PPARγ; IP Receptor; Bacterial
References
[1] Patent: CN105924456, 2016, A. Location in patent: Paragraph 0033; 0035
(6R-(6-alpha,7-alpha))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt Preparation Products And Raw materials
Raw materials
Preparation Products
(6R-(6-alpha,7-alpha))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt Suppliers
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- Country
- India
- ProdList
- 6100
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View Lastest Price from (6R-(6-alpha,7-alpha))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt manufacturers
- Product
- (6R-(6-alpha,7-alpha))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)... 75498-96-3
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-10-18
- Product
- Cefminox sodium 75498-96-3
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-08-07