5'-Amino-2'-hydroxyacetophenone

Product Name: 5'-Amino-2'-hydroxyacetophenone
CAS No.: 50-80-6
Chemical Name: 5'-Amino-2'-hydroxyacetophenone
Synonyms: 1-(5-Amino-2-hydroxyphenyl);5'-Amino-2'-hydroxyacetophenone;Ethanone, 1-(5-amino-2-hydroxyphenyl)-;5''-AMINO-2''-HYDROXYACETOPHENONE {1-(5-AMINO-2-HYDROXYPHENYL)ETHANONE}
CBNumber: CB01103353
Molecular Formula: C8H9NO2
Formula Weight: 151.16
MOL File: 50-80-6.mol

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5'-Amino-2'-hydroxyacetophenone Property

Melting point:: 121–122°C
Boiling point:: 335.4±27.0 °C(Predicted)
Density: 1.242±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 10.42±0.18(Predicted)
Appearance: Light yellow to yellow Solid

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Safety

HS Code: 2914500090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TRC

Product number: A611475
Product name: 1-(5-Amino-2-hydroxyphenyl)ethanone
Packaging: 50mg
Price: $55
Updated: 2021/12/16

TRC

Product number: A611475
Product name: 1-(5-Amino-2-hydroxyphenyl)ethanone
Packaging: 1g
Price: $545
Updated: 2021/12/16

AK Scientific

Product number: 7032AB
Product name: 1-(5-Amino-2-hydroxyphenyl)ethanone
Packaging: 10g
Price: $1137
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA70776
Product name: 5-Amino-2-hydroxyacetophenone
Packaging: 250mg
Price: $65
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA70776
Product name: 5-Amino-2-hydroxyacetophenone
Packaging: 500mg
Price: $100
Updated: 2021/12/16

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5'-Amino-2'-hydroxyacetophenone Chemical Properties,Usage,Production

Uses

1-(5-Amino-2-hydroxyphenyl)ethanone is used in the preparation of alkylated flavonoid compounds for use as therapeutic antioxidants. It is also used to synthesize spiro[chromanone-piperidine]s as acetyl-CoA carboxylase inhibitors.

Preparation

Also obtained by refluxing a suspension of N-(3-acetyl-4- hydroxyphenyl)acetamide in 15% hydrochloric acid for 40 min (84%).

Synthesis

7298-67-1

50-80-6

The hydrolysis reaction was carried out by refluxing 2-hydroxy-5-acetamidoacetophenone in 2N hydrochloric acid solution for 6 hours to obtain 5-amino-2-hydroxyacetophenone in 94% yield.

References

[1] Journal of Medicinal Chemistry, 1992, vol. 35, # 21, p. 3973 - 3976
[2] Patent: US2007/117823, 2007, A1. Location in patent: Page/Page column 8
[3] Patent: WO2007/54580, 2007, A1. Location in patent: Page/Page column 16
[4] European Journal of Medicinal Chemistry, 1991, vol. 26, # 9, p. 843 - 851
[5] Bioorganic and Medicinal Chemistry, 2004, vol. 12, # 9, p. 2079 - 2098

5'-Amino-2'-hydroxyacetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

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5'-Amino-2'-hydroxyacetophenone Suppliers

Canada 1 China 55 India 5 United Kingdom 2 United States 5 Global 68

Capot Chemical Co., Ltd

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View Lastest Price from 5'-Amino-2'-hydroxyacetophenone manufacturers

Career Henan Chemica Co

Product: 5'-Amino-2'-hydroxyacetophenone 50-80-6
Price: US $1.00/g
Min. Order: 1g
Purity: 85.0-99.8%
Supply Ability: 20tons
Release date: 2020-10-28

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1-(5-Amino-2-hydroxyphenyl)

5''-AMINO-2''-HYDROXYACETOPHENONE {1-(5-AMINO-2-HYDROXYPHENYL)ETHANONE}

Ethanone, 1-(5-amino-2-hydroxyphenyl)-

5'-Amino-2'-hydroxyacetophenone

50-80-6