ChemicalBook > CAS DataBase List > 4-Bromo-5-chloro-2-fluoroaniline

4-Bromo-5-chloro-2-fluoroaniline

Product Name
4-Bromo-5-chloro-2-fluoroaniline
CAS No.
116369-24-5
Chemical Name
4-Bromo-5-chloro-2-fluoroaniline
Synonyms
4-Bromo-5-chloro-2-fluoroaniline;2-Fluoro-4-Bromo-5-Chloroaniline;Benzenamine, 4-bromo-5-chloro-2-fluoro-
CBNumber
CB01115547
Molecular Formula
C6H4BrClFN
Formula Weight
224.46
MOL File
Mol file
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4-Bromo-5-chloro-2-fluoroaniline Property

Boiling point:
258.9±35.0 °C(Predicted)
Density 
1.809±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
1.44±0.10(Predicted)
Appearance
Off-white to gray Solid
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Safety

HS Code 
2921490090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B687743
Product name
4-Bromo-5-chloro-2-fluoroaniline
Packaging
100mg
Price
$60
Updated
2021/12/16
AK Scientific
Product number
1542CV
Product name
4-Bromo-5-chloro-2-fluoroaniline
Packaging
250mg
Price
$88
Updated
2021/12/16
Apolloscientific
Product number
PC502456
Product name
4-Bromo-5-chloro-2-fluoroaniline
Packaging
1g
Price
$131
Updated
2021/12/16
SynQuest Laboratories
Product number
3630-F-0A
Product name
4-Bromo-5-chloro-2-fluoroaniline
Packaging
1g
Price
$144
Updated
2021/12/16
Apolloscientific
Product number
PC502456
Product name
4-Bromo-5-chloro-2-fluoroaniline
Packaging
5g
Price
$399
Updated
2021/12/16
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4-Bromo-5-chloro-2-fluoroaniline Chemical Properties,Usage,Production

Synthesis

2106-05-0

116369-24-5

General procedure for the synthesis of 4-bromo-5-chloro-2-fluoroaniline from 2-fluoro-5-chloroaniline: N-bromosuccinimide (1 eq.) was added to a solution of 5-chloro-2-fluoroaniline (1 eq.) in acetonitrile (0.5 M) at 25 °C. The reaction mixture was stirred at 25 °C for 1 hour. After completion of the reaction, the mixture was concentrated to dryness and the residue obtained was purified by silica gel column chromatography to afford 4-bromo-5-chloro-2-fluoroaniline in 91% yield as a yellow oil.1H NMR (400 MHz, CDCl3) δppm: 7.23 (d, J = 10.2 Hz, 1H), 6.88 (d, J = 8.4 Hz, 1H), 3.92- 2.64 (br, 2H).

References

[1] Patent: US2016/96841, 2016, A1. Location in patent: Paragraph 0370

4-Bromo-5-chloro-2-fluoroaniline Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Bromo-5-chloro-2-fluoroaniline Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
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Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
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sales@sinch.com.cn
Country
China
ProdList
11598
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Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
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Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15883
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Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
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Country
China
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Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
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China
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Shanghai HuanChuan Industry Co.,Ltd.
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Changzhou Tianrui Pharmaceutical Technology Co., Ltd.
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116369-24-5, 4-Bromo-5-chloro-2-fluoroanilineRelated Search:


  • 4-Bromo-5-chloro-2-fluoroaniline
  • Benzenamine, 4-bromo-5-chloro-2-fluoro-
  • 2-Fluoro-4-Bromo-5-Chloroaniline
  • 116369-24-5