ChemicalBook > CAS DataBase List > Minalrestat

Minalrestat

Product Name
Minalrestat
CAS No.
129688-50-2
Chemical Name
Minalrestat
Synonyms
ARI509;ARI-509;WAYARI-509;WAY-ARI-509;Minalrestat;Unii-G44pe6qb31;2-(4-Bromo-2-fluorobenzyl)-6-fluoro-1H-spiro[isoquinoline-4,3'-pyrrolidine]-1,2',3,5'(2H)-tetraone;Spiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrone, 2-[(4-bromo-2-fluorophenyl)methyl]-6-fluoro-
CBNumber
CB01117314
Molecular Formula
C19H11BrF2N2O4
Formula Weight
449.206
MOL File
129688-50-2.mol
More
Less

Minalrestat Property

Melting point:
231-232℃
Density 
1.45
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
INB0004048
Product name
MINALRESTAT
Purity
95.00%
Packaging
5MG
Price
$496.89
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
18701
Product name
Minalrestat
Packaging
25mg
Price
$1500
Updated
2021/12/16
More
Less

Minalrestat Chemical Properties,Usage,Production

Uses

Inhibitor(aldose reductase).

Definition

ChEBI: Minalrestat is a member of isoquinolines.

in vivo

Minalrestat (Oral gavage, 10 mg/kg/day, for 30 days) corrects the decreased microvascular reactivity in diabetic rats[1].
Minalrestat (Oral gavage, 10 mg/kg) restores the reduced number of leukocytes adhered and migrated leukocytes in postcapillary venules in diabetic rats[2].

Animal Model:Alloxan (40 mg/kg i.v.)-induced diabetic rats[1]
Dosage:10 mg/kg/day
Administration:Oral gavage, for 30 days.
Result:Restored the decreased microvascular reactivity.

Minalrestat Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Minalrestat Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32159
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49732
Advantage
58
Suzhou Zhixin Biotechnology Co., Ltd.
Tel
0512-65118909 15162312715
Email
sales@szzxbio.com
Country
China
ProdList
2972
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11973
Advantage
58
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
19717
Advantage
58
Sangon Biotech (Shanghai) Co.,Ltd.
Tel
400-821-026
Email
Sales@sangon.com
Country
China
ProdList
47255
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Wuhan Han Sheng New Material Technology Co.,Ltd
Tel
+8617798174412
Email
admin01@hsnm.com.cn
Country
China
ProdList
2097
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38630
Advantage
58