Minalrestat

Product Name: Minalrestat
CAS No.: 129688-50-2
Chemical Name: Minalrestat
Synonyms: ARI509;ARI-509;WAYARI-509;WAY-ARI-509;Minalrestat;Unii-G44pe6qb31;2-(4-Bromo-2-fluorobenzyl)-6-fluoro-1H-spiro[isoquinoline-4,3'-pyrrolidine]-1,2',3,5'(2H)-tetraone;Spiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrone, 2-[(4-bromo-2-fluorophenyl)methyl]-6-fluoro-
CBNumber: CB01117314
Molecular Formula: C19H11BrF2N2O4
Formula Weight: 449.206
MOL File: 129688-50-2.mol

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Minalrestat Property

Melting point:: 231-232℃
Density: 1.45

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: INB0004048
Product name: MINALRESTAT
Purity: 95.00%
Packaging: 5MG
Price: $496.89
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 18701
Product name: Minalrestat
Packaging: 25mg
Price: $1500
Updated: 2021/12/16

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Minalrestat Chemical Properties,Usage,Production

Uses

Inhibitor(aldose reductase).

Definition

ChEBI: Minalrestat is a member of isoquinolines.

in vivo

Minalrestat (Oral gavage, 10 mg/kg/day, for 30 days) corrects the decreased microvascular reactivity in diabetic rats^[1].
Minalrestat (Oral gavage, 10 mg/kg) restores the reduced number of leukocytes adhered and migrated leukocytes in postcapillary venules in diabetic rats^[2].

Animal Model:	Alloxan (40 mg/kg i.v.)-induced diabetic rats^[1]
Dosage:	10 mg/kg/day
Administration:	Oral gavage, for 30 days.
Result:	Restored the decreased microvascular reactivity.

Minalrestat Preparation Products And Raw materials

Raw materials

Preparation Products

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Minalrestat Suppliers

China 10 United Kingdom 1 United States 6 Global 17

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32467
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49977
Advantage: 58

Suzhou Zhixin Biotechnology Co., Ltd.

Tel: 0512-65118909 18100677375
Email: sales@szzxbio.com
Country: China
ProdList: 3000
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11972
Advantage: 58

TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.cn
Country: China
ProdList: 29430
Advantage: 58

Sangon Biotech (Shanghai) Co.,Ltd.

Tel: 400-821-026
Email: Sales@sangon.com
Country: China
ProdList: 6813
Advantage: 58

Shanghai Amole Biotechnology Co., Ltd.

Tel: 18916360931 18916360931
Email: 2596183085@qq.com
Country: China
ProdList: 17238
Advantage: 58

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63687
Advantage: 58

Wuhan Han Sheng New Material Technology Co.，Ltd

Tel: +8617798174412
Email: admin01@hsnm.com.cn
Country: China
ProdList: 2097
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354;
Email: support@targetmol.com
Country: United States
ProdList: 39040
Advantage: 58

129688-50-2, MinalrestatRelated Search:

4-Fluoro-2-methylbenzylamine 3-(3-FLUOROPHENYL)PYRROLIDINE 4-BROMO-2-FLUOROBENZYLAMINE ALPHA-METHYL-ALPHA-PHENYLSUCCINIMIDE 4,4-DIMETHYL-1,2,3,4-TETRAHYDROISOQUINOLINE CHEMBRDG-BB 5937785 6-FLUORO-1,2,3,4-TETRAHYDRO-ISOQUINOLINE 4-FLUORO-N,2-DIMETHYLBENZAMIDE 2-ETHYL-2-PHENYLMALONAMIDE HYDRATE CHEMBRDG-BB 5402696 6-FLUORO-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE 2-(5-FLUORO-2-METHYLPHENYL)ACETALDEHYDE BENZYL-(2-FLUORO-BENZYL)-AMINE 4-METHYL-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE CHEMBRDG-BB 9071372 3-DIETHYLAMINO-2,2-DIMETHYL-PROPIONALDEHYDE Minalrestat 4-(Aminomethyl)-1,2-dihydroisoquinolin-3(4H)-one

2-(4-Bromo-2-fluorobenzyl)-6-fluoro-1H-spiro[isoquinoline-4,3'-pyrrolidine]-1,2',3,5'(2H)-tetraone

Unii-G44pe6qb31

Minalrestat

Spiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrone, 2-[(4-bromo-2-fluorophenyl)methyl]-6-fluoro-

ARI509

ARI-509

WAY-ARI-509

WAYARI-509

129688-50-2

C19H11BrF2N2O4