3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine

Product Name: 3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine
CAS No.: 306387-90-6
Chemical Name: 3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine
Synonyms: KAAD Cyclopamine,KAADCyclopamine;3-Keto-N-aminoethyl-N’-aminocaproyldihydrocinnamoyl Cyclopamine;3-Keto-N-aMinoethyl-N'-aMinocaproyldihydrocinnaMoyl CyclopaMine, >80%;Benzenepropanamide, N-[6-[[2-[(3'R,3'aS,6'S,6aS,6bS,7'aR,2'R,11aS,11bR)-1,2,3,3',3'a,4,5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-octadecahydro-3',6',10,11b-tetramethyl-3-oxospiro[9H-benzo[a]fluorene-9,2'(4'H)-furo[3,2-b]pyridin]-4'-yl]ethyl]amino]-6-oxohexyl]-
CBNumber: CB01175752
Molecular Formula: C44H63N3O4
Formula Weight: 697.999
MOL File: 306387-90-6.mol

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3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine Property

Boiling point:: 875.6±65.0 °C(Predicted)
Density: 1.15±0.1 g/cm3(Predicted)
storage temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility: Chloroform: Slightly soluble; Methanol: Slightly soluble
form: A solid
pka: 16.10±0.46(Predicted)
color: White to light yellow
CAS DataBase Reference: 306387-90-6

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 20943
Product name: Cyclopamine-KAAD
Purity: ≥95%
Packaging: 500μg
Price: $480
Updated: 2024/03/01

Cayman Chemical

Product number: 20943
Product name: Cyclopamine-KAAD
Purity: ≥95%
Packaging: 1mg
Price: $869
Updated: 2024/03/01

TRC

Product number: K171000
Product name: 3-Keto-N-aminoethyl-N’-aminocaproyldihydrocinnamoylCyclopamine
Packaging: 5mg
Price: $510
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC158406
Product name: Cyclopamine- KAAD
Packaging: 1mg
Price: $250
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC158406
Product name: Cyclopamine- KAAD
Packaging: 2mg
Price: $420
Updated: 2021/12/16

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3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

Cyclopamine demonstrates teratogenic properties and has been shown to reverse effects ofoncogenic mutations in Smoothened and Patched.1 The KAAD derivative has shown 10-20 fold higher potency than cyclopamine in inhibition of ?-Galactosidase expression i

Uses

Cyclopamine demonstrates teratogenic properties and has been shown to reverse effects of oncogenic mutations in Smoothened and Patched.1 The KAAD-Cyclopamine has shown 10-20 fold higher potency than cyclopamine in inhibition of ?-Galactosidase expression in p2Ptch-1- cells, with similar or lower toxicity.KAAD-Cyclopamine compound is unstable in solution.

3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine Suppliers

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306387-90-6, 3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl CyclopamineRelated Search:

3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine 3-(ALLYLOXY)PIPERIDINE CHEMBRDG-BB 4018237

3-Keto-N-aMinoethyl-N'-aMinocaproyldihydrocinnaMoyl CyclopaMine, >80%

Benzenepropanamide, N-[6-[[2-[(3'R,3'aS,6'S,6aS,6bS,7'aR,2'R,11aS,11bR)-1,2,3,3',3'a,4,5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-octadecahydro-3',6',10,11b-tetramethyl-3-oxospiro[9H-benzo[a]fluorene-9,2'(4'H)-furo[3,2-b]pyridin]-4'-yl]ethyl]amino]-6-oxohexyl]-

KAAD Cyclopamine,KAADCyclopamine

3-Keto-N-aminoethyl-N’-aminocaproyldihydrocinnamoyl Cyclopamine

306387-90-6

C44H63N3O4

Inhibitors

Steroids

Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids