ChemicalBook > CAS DataBase List > 3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine

3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine

Product Name
3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine
CAS No.
306387-90-6
Chemical Name
3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine
Synonyms
KAAD Cyclopamine,KAADCyclopamine;3-Keto-N-aMinoethyl-N'-aMinocaproyldihydrocinnaMoyl CyclopaMine, >80%;Benzenepropanamide, N-[6-[[2-[(3'R,3'aS,6'S,6aS,6bS,7'aR,2'R,11aS,11bR)-1,2,3,3',3'a,4,5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-octadecahydro-3',6',10,11b-tetramethyl-3-oxospiro[9H-benzo[a]fluorene-9,2'(4'H)-furo[3,2-b]pyridin]-4'-yl]ethyl]amino]-6-oxohexyl]-
CBNumber
CB01175752
Molecular Formula
C44H63N3O4
Formula Weight
697.999
MOL File
306387-90-6.mol
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3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine Property

Boiling point:
875.6±65.0 °C(Predicted)
Density 
1.15±0.1 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility 
Chloroform: Slightly soluble; Methanol: Slightly soluble
form 
A solid
pka
16.10±0.46(Predicted)
CAS DataBase Reference
306387-90-6
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
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N-Bromosuccinimide Price

Cayman Chemical
Product number
20943
Product name
Cyclopamine-KAAD
Purity
≥95%
Packaging
500μg
Price
$480
Updated
2024/03/01
Cayman Chemical
Product number
20943
Product name
Cyclopamine-KAAD
Purity
≥95%
Packaging
1mg
Price
$869
Updated
2024/03/01
TRC
Product number
K171000
Product name
3-Keto-N-aminoethyl-N’-aminocaproyldihydrocinnamoylCyclopamine
Packaging
5mg
Price
$510
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC158406
Product name
Cyclopamine- KAAD
Packaging
5mg
Price
$800
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC158406
Product name
Cyclopamine- KAAD
Packaging
1mg
Price
$250
Updated
2021/12/16
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3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

Cyclopamine demonstrates teratogenic properties and has been shown to reverse effects ofoncogenic mutations in Smoothened and Patched.1 The KAAD derivative has shown 10-20 fold higher potency than cyclopamine in inhibition of ?-Galactosidase expression i

Uses

Cyclopamine demonstrates teratogenic properties and has been shown to reverse effects of oncogenic mutations in Smoothened and Patched.1 The KAAD-Cyclopamine has shown 10-20 fold higher potency than cyclopamine in inhibition of ?-Galactosidase expression in p2Ptch-1- cells, with similar or lower toxicity.KAAD-Cyclopamine compound is unstable in solution.

3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine Suppliers

306387-90-6, 3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl CyclopamineRelated Search:


  • 3-Keto-N-aMinoethyl-N'-aMinocaproyldihydrocinnaMoyl CyclopaMine, >80%
  • Benzenepropanamide, N-[6-[[2-[(3'R,3'aS,6'S,6aS,6bS,7'aR,2'R,11aS,11bR)-1,2,3,3',3'a,4,5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-octadecahydro-3',6',10,11b-tetramethyl-3-oxospiro[9H-benzo[a]fluorene-9,2'(4'H)-furo[3,2-b]pyridin]-4'-yl]ethyl]amino]-6-oxohexyl]-
  • KAAD Cyclopamine,KAADCyclopamine
  • 306387-90-6
  • C44H63N3O4
  • Inhibitors
  • Steroids
  • Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids