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Ramipril Diketopiperazine

Product Name
Ramipril Diketopiperazine
CAS No.
108731-95-9
Chemical Name
Ramipril Diketopiperazine
Synonyms
Ramipril EP Imp D;Ramipril Impurity 32;Ramipril EP Imurity D;RaMipril EP IMpurity D;RaMipril IMpurity-D (EP);Ramipril Diketopiperazine;Ramipril impurity D (R0145020);Ramipril USP Related Compound D;Ramipril Related Compound D/EP impurity D;Ramipril diketopiperazine (EP Impurity D)
CBNumber
CB01176764
Molecular Formula
C23H30N2O4
Formula Weight
398.5
MOL File
108731-95-9.mol
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Ramipril Diketopiperazine Property

Boiling point:
597.4±50.0 °C(Predicted)
Density 
1.22±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: soluble,Ethanol: soluble
pka
-1.16±0.40(Predicted)
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
R0145020
Product name
Ramipril impurity D
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
10 mg
Price
$225
Updated
2025/07/31
Sigma-Aldrich
Product number
1598347
Product name
Ramipril Related Compound D
Packaging
20mg
Price
$1200
Updated
2025/07/31
Sigma-Aldrich
Product number
R0145020
Product name
Ramipril impurity D
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
r0145020
Price
$220
Updated
2024/03/01
TRC
Product number
R111008
Product name
RamiprilDiketopiperazine
Packaging
1mg
Price
$110
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0000802
Product name
RAMIPRIL DIKETOPIPERAZINE
Purity
95.00%
Packaging
1MG
Price
$899.85
Updated
2021/12/16
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Ramipril Diketopiperazine Chemical Properties,Usage,Production

Uses

Ramipril Diketopiperazine (Ramipril EP Impurity D) is a metabolite of Ramipril (R111000).

Uses

A metabolite of Ramipril (R111000).

Ramipril Diketopiperazine Preparation Products And Raw materials

Raw materials

Preparation Products

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108731-95-9, Ramipril DiketopiperazineRelated Search:


  • [3S-[2(R*),3a,5ab,8ab,9ab]]-Decahydro-3-methyl-1,4-dioxo-a-(2-phenylethyl)-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic Acid Ethyl Ester
  • [3S-[2(R*),3a,5a,8a,9a]]-Decahydro-3-methyl-1,4-dioxo-a-(2-phenylethyl)-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic Acid Ethyl Ester
  • (αS,3S,5aS,8aS,9aS)-Decahydro-3-Methyl-1,4-dioxo-α-(2-phenylethyl)-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic Acid Ethyl Ester
  • [3S-[2(R*),3α,5aβ,8aβ,9aβ]]-Decahydro-3-Methyl-1,4-dioxo-α-(2-phenylethyl)-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic Acid Ethyl Ester
  • RaMipril IMpurity-D (EP)
  • RaMipril EP IMpurity D
  • Ethyl (2S)2-[(3S,5aS,8aS, 9aS)-3-methyl-1,4-dioxodecahydro-1H-cyclopenta[e]pyrrolo[1,2-a]pyrazin-2-yl]-4-phenylbutanoate
  • Ethyl (2S)-2-[(3S,5aS,8aS,9aS)-3-methyl-1,4-dioxodecahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-2-yl]-4-phenyl butanoate
  • Ramipril Impurity 4(Ramipril EP Impurity D)
  • Ramipril EP Imp D
  • Ramipril Impurity Ⅳ:Ramipril Diketopiperazine
  • ethyl 2-(2-methyl-1,4-dioxo-2,4a,5,5a,6,7,8,8a-octahydrocyclopenta[3,4]pyrrolo[3,5-c]pyrazin-3-yl)-4-phenylbutanoate
  • ethyl (2R)-2-[(2S,4aS,5aS,8aS)-2-methyl-1,4-dioxo-2,4a,5,5a,6,7,8,8a-octahydrocyclopenta[3,4]pyrrolo[3,5-c]pyrazin-3-yl]-4-phenylbutanoate
  • Ramipril EP Imurity D
  • Ramipril EP Impurity D (RamiprilDiketopiperazine)
  • Ramipril EP Impurity D/ Ramipril Related Compund D (Ramipril Diketopiperazine)
  • Ramipril EP Impurity DQ: What is Ramipril EP Impurity D Q: What is the CAS Number of Ramipril EP Impurity D Q: What is the storage condition of Ramipril EP Impurity D Q: What are the applications of Ramipril EP Impurity D
  • Ramipril impurity D (R0145020)
  • Ramipril USP Related Compound D
  • 2H-Cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic acid, decahydro-3-methyl-1,4-dioxo-α-(2-phenylethyl)-, ethyl ester, (αS,3S,5aS,8aS,9aS)-
  • (S)-Ethyl 2-((3S,5aS,8aS,9aS)-3-methyl-1,4-dioxooctahydro-1H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-2(5aH)-yl)-4-phenylbutanoate (Ramipril Impurity)
  • Diethyl 2,2'-(2,5-dimethyl-3,6-dioxo-piperazine-1,4-diyl)bis(4-phenylbutanoate)
  • Ramipril Related Compound D/EP impurity D
  • Ethyl (2S)-2-[(3S,5aS,8aS,9aS)-3-Methyl-1,4-dioxodecahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-2
  • Ramipril Impurity 32
  • Ethyl (2<i>S</i>)2-[(3<i>S</i>,5a<i>S</i>,8a<i>S</i>, 9a<i>S</i>)-3-methyl-1,4-dioxodecahydro-1<i>H</i>-cyclopenta[<i>e</i>]pyrrolo[1,2-<i>a</i>]pyrazin-2-yl]-4-phenylbutanoate
  • Ramipril diketopiperazine (EP Impurity D)
  • Ramipril Impurity Ⅳ:Ramipril Diketopiperazine
  • Ethyl (2S)-2-[(3S,5aS,8aS,9aS)-3-Methyl-1,4-dioxodecahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-2-yl]-4-phenylbutanoate (Ramipril Diketopiperazine)
  • Ramipril Imp. D (EP): Ethyl(2S)-2-(3S,5aS,8aS,9aS)-3-methyl-1,4-dioxodecahydro-2H-cyclopenta4,5pyrrolo1,2-apyrazin-2-yl4-phenyl-butanoate
  • Ramipril Diketopiperazine
  • 108731-95-9
  • 108731-95-5
  • 3985
  • Aromatics
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals