ChemicalBook > CAS DataBase List > Cafedrine
Cafedrine
- Product Name
- Cafedrine
- CAS No.
- 58166-83-9
- Chemical Name
- Cafedrine
- Synonyms
- Cafedrine;Cafedrina;Brn 0583473;l-Cafedrine;(-)-Cafedrine;Cafedrina [inn-spanish];7-(2-(2-Hydroxy-1-methylphenethylamino)ethyl)theophylline;7-(2-(beta-Hydroxy-alpha-methylphenethylamino)ethyl)theophylline;7-[2-(β-Hydroxy-α-methylphenethylamino)ethyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione;3,7-Dihydro-7-[2-[(2-hydroxy-1-methyl-2-phenylethyl)amino]ethyl]-1,3-dimethyl-1H-purine-2,6-dione
- CBNumber
- CB01178203
- Molecular Formula
- C18H23N5O3
- Formula Weight
- 357.412
- MOL File
- 58166-83-9.mol
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Cafedrine Property
- Boiling point:
- 591.6±52.0 °C(Predicted)
- Density
- 1.33±0.1 g/cm3(Predicted)
- pka
- 13.90±0.20(Predicted)
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N-Bromosuccinimide Price
TRC
- Product number
- C799035
- Product name
- (-)-Cafedrine
- Packaging
- 5mg
- Price
- $50
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0010919
- Product name
- CAFEDRINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $497.41
- Updated
- 2021/12/16
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Cafedrine Chemical Properties,Usage,Production
Originator
Praxinor,Merck Lipha Sante
Uses
(-)-Cafedrine is composed of linked Phenylpropanolamine (P336100) and Theophylline (T343850). It is used to regulate and restore blood pressure.
Manufacturing Process
7.5 g 7-(2-bromethyl)theophylline, 11.3 g 1-norphedrine and 12.5 ml
isopropanol were refluxed with stirring for 6 hours. Then 30 ml ethanol and
HCl in ethanol to pH 5-6 were added. The mixture stood for 2 days. 9.6 g of
7-(2-(beta-hydroxy-alpha-methylphenethylamino)ethyl)theophylline
hydrochloride was filtered off and dried. MP 243°-244°C.
In practice it is usually used as free base.
Therapeutic Function
Analeptic
Cafedrine Preparation Products And Raw materials
Raw materials
Preparation Products
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