ChemicalBook > CAS DataBase List > Cafedrine

Cafedrine

Product Name
Cafedrine
CAS No.
58166-83-9
Chemical Name
Cafedrine
Synonyms
Cafedrine;Cafedrina;Brn 0583473;l-Cafedrine;(-)-Cafedrine;Cafedrina [inn-spanish];7-(2-(2-Hydroxy-1-methylphenethylamino)ethyl)theophylline;7-(2-(beta-Hydroxy-alpha-methylphenethylamino)ethyl)theophylline;7-[2-(β-Hydroxy-α-methylphenethylamino)ethyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione;3,7-Dihydro-7-[2-[(2-hydroxy-1-methyl-2-phenylethyl)amino]ethyl]-1,3-dimethyl-1H-purine-2,6-dione
CBNumber
CB01178203
Molecular Formula
C18H23N5O3
Formula Weight
357.412
MOL File
58166-83-9.mol
More
Less

Cafedrine Property

Boiling point:
591.6±52.0 °C(Predicted)
Density 
1.33±0.1 g/cm3(Predicted)
pka
13.90±0.20(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

TRC
Product number
C799035
Product name
(-)-Cafedrine
Packaging
5mg
Price
$50
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0010919
Product name
CAFEDRINE
Purity
95.00%
Packaging
5MG
Price
$497.41
Updated
2021/12/16
More
Less

Cafedrine Chemical Properties,Usage,Production

Originator

Praxinor,Merck Lipha Sante

Uses

(-)-Cafedrine is composed of linked Phenylpropanolamine (P336100) and Theophylline (T343850). It is used to regulate and restore blood pressure.

Manufacturing Process

7.5 g 7-(2-bromethyl)theophylline, 11.3 g 1-norphedrine and 12.5 ml isopropanol were refluxed with stirring for 6 hours. Then 30 ml ethanol and HCl in ethanol to pH 5-6 were added. The mixture stood for 2 days. 9.6 g of 7-(2-(beta-hydroxy-alpha-methylphenethylamino)ethyl)theophylline hydrochloride was filtered off and dried. MP 243°-244°C.
In practice it is usually used as free base.

Therapeutic Function

Analeptic

Cafedrine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Cafedrine Suppliers

Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28172
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11974
Advantage
58
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
19704
Advantage
58
Lanospharma Laboratories Co.,Ltd
Tel
--
Fax
--
Email
sales@lanospharma.com
Country
China
ProdList
6329
Advantage
56

58166-83-9, CafedrineRelated Search:


  • Cafedrine
  • 3,7-Dihydro-7-[2-[(2-hydroxy-1-methyl-2-phenylethyl)amino]ethyl]-1,3-dimethyl-1H-purine-2,6-dione
  • 7-[2-(β-Hydroxy-α-methylphenethylamino)ethyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
  • 7-(2-((Alphas,betar)-beta-hydroxy-alpha-methylphenethylamino)ethyl)-1,3-dimethyl-2,6(1H,3H)purindion
  • 7-(2-(2-Hydroxy-1-methylphenethylamino)ethyl)theophylline
  • 7-(2-{[(1R,2S)-1-Hydroxy-1-phenyl-2-propanyl]amino}ethyl)-1,3-dim ethyl-3,7-dihydro-1H-purine-2,6-dione
  • 7-(2-(beta-Hydroxy-alpha-methylphenethylamino)ethyl)theophylline
  • Brn 0583473
  • Cafedrina
  • Cafedrina [inn-spanish]
  • 1H-Purine-2,6-dione, 3,7-dihydro-7-[2-[[(1S,2R)-2-hydroxy-1-methyl-2-phenylethyl]amino]ethyl]-1,3-dimethyl-
  • (-)-Cafedrine
  • l-Cafedrine
  • 58166-83-9